LIN7C Antikörper (AA 86-197) (Cy5.5)

Produktnummer ABIN1411715

Der Kaninchen Polyklonal Anti-LIN7C-Antikörper wurde für WB, IF (cc) und IF (p) validiert. Er ist geeignet, LIN7C in Proben von Human zu detektieren.

Kurzübersicht für LIN7C Antikörper (AA 86-197) (Cy5.5) (ABIN1411715)

Target: LIN7C (Lin-7 Homolog C (LIN7C))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LIN7C Antikörper ist konjugiert mit Cy5.5

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-LIN7C Antikörper (Cy5.5)

Bindungsspezifität: AA 86-197

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Zebrafish

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human LIN7C

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu LIN7C

Target: LIN7C (Lin-7 Homolog C (LIN7C))

Andere Bezeichnung: LIN7C

Hintergrund:

Synonyms: LIN 7 C, Lin 7 homolog C C. elegans, LIN 7 protein 3, LIN 7C, LIN7 protein 3, MALS 3, MALS3, Mammalian lin seven protein 3, Veli 3 protein, VELI3, Vertebrate lin 7 homolog 3, LIN7C_HUMAN.

Background: Velis are a family of small synaptic proteins that interact with other proteins at the post-synaptic density (PSD) of neuronal synapses. Velis contain the PDZ motif involved in recruiting cell adhesion molecules, receptors, and channels. Veli1 (also designated Lin-7A and MALS-1), Veli2 (also designated Lin-7B and MALS-2), and Veli3 (also designated Lin-7C and MALS-3) are mammalian homologs of C. elegans LIN-7. Veli proteins are ubiquitously expressed with high expression in brain, liver, and testis. Velis are localized at the synaptic junctions in neurons. Velis bind to CASK, a neurexin-binding protein highly concentrated in synapses, and Mint1, a binding partner with a vesicle trafficking protein.

Pathways: Synaptic Membrane