Phospholipase C beta 1 Antikörper (AA 441-540) (FITC)

Produktnummer ABIN1397747

Der Kaninchen Polyklonal Anti-Phospholipase C beta 1-Antikörper wurde für WB, FACS, IF (cc) und IF (p) validiert. Er ist geeignet, Phospholipase C beta 1 in Proben von Human und Ratte zu detektieren.

Kurzübersicht für Phospholipase C beta 1 Antikörper (AA 441-540) (FITC) (ABIN1397747)

Target: Phospholipase C beta 1 (PLCB1) (phospholipase C, beta 1 (phosphoinositide-Specific) (PLCB1))

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Phospholipase C beta 1 Antikörper ist konjugiert mit FITC

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-Phospholipase C beta 1 Antikörper (FITC)

Bindungsspezifität: AA 441-540

Kreuzreaktivität: Human, Ratte

Homologie: Mouse,Dog,Cow,Horse,Chicken

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Phospholipase C beta 1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu Phospholipase C beta 1

Target: Phospholipase C beta 1 (PLCB1) (phospholipase C, beta 1 (phosphoinositide-Specific) (PLCB1))

Andere Bezeichnung: Phospholipase C beta 1

Hintergrund:

Synonyms: 1-phosphatidylinositol-45-bisphosphate phosphodiesterase beta 1, 1vphosphatidylinositol 4,5 bisphosphate phosphodiesterase beta 1 , Phosphb, Phosphoinositide phospholipase C, Phosphoinositide phospholipase C-beta 1, Phospholipase C beta 1 phosphoinositide-specic, Phospholipase C I, PI PLC, PLC 1, PLC_1, PLC-154, PLC-beta-1, PLC-I, PLC154, Plcb, PLCB1, Plcb1 protein, PLCbeta1.

Background: Phospholipase C beta 1 catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of many extracellular signals. Its gene is activated by two G-protein alpha subunits, alpha-q and alpha-11. Two transcript variants encoding different isoforms have been found for its gene.

Gen-ID: 23236

Pathways: WNT Signalweg, AMPK Signaling, Thyroid Hormone Synthesis, Inositol Metabolic Process, Regulation of Muscle Cell Differentiation, Regulation of G-Protein Coupled Receptor Protein Signaling, Proton Transport, Skeletal Muscle Fiber Development, CXCR4-mediated Signaling Events, G-protein mediated Events