UNC93B1 Antikörper (AA 451-550)

Produktnummer ABIN1386855

Dieses Anti-UNC93B1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von UNC93B1 in ELISA, IHC (p), IF (cc), IF (p) und IHC (fro). Geeignet für Human.

Kurzübersicht für UNC93B1 Antikörper (AA 451-550) (ABIN1386855)

Target: UNC93B1 (Unc-93 Homolog B1 (UNC93B1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser UNC93B1 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-UNC93B1 Antikörper

Bindungsspezifität: AA 451-550

Homologie: Human,Mouse,Rat

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human UNC93B

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu UNC93B1

Target: UNC93B1 (Unc-93 Homolog B1 (UNC93B1))

Andere Bezeichnung: UNC93B

Hintergrund:

Synonyms: IIAE1, UNC93, UNC93B, Unc-93B1, Protein unc-93 homolog B1, hUNC93B1, UNC93B1

Background: Plays an important role in innate and adaptive immunity by regulating nucleotide-sensing Toll-like receptor (TLR) signaling. Required for the transport of a subset of TLRs (including TLR3, TLR7 and TLR9) from the endoplasmic reticulum to endolysosomes where they can engage pathogen nucleotides and activate signaling cascades. May play a role in autoreactive B-cells removal.

Gen-ID: 81622

UniProt: Q9H1C4

Pathways: TLR Signalweg, Activation of Innate immune Response, Toll-Like Receptors Cascades