c-MET Antikörper
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- Target Alle c-MET (MET) Antikörper anzeigen
- c-MET (MET) (Met Proto-Oncogene (MET))
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Reaktivität
- Human
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Wirt
- Ratte
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Klonalität
- Monoklonal
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Konjugat
- Dieser c-MET Antikörper ist unkonjugiert
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Applikation
- Flow Cytometry (FACS), Cell-ELISA (cELISA)
- Spezifität
- Anti-human c-Met
- Produktmerkmale
- Selection: Based on recognition of the complete native protein expressed on transfected mammalian cells
- Aufreinigung
- Protein G
- Immunogen
- genetic immunisation with cDNA encoding human c-Met
- Klon
- BCI-3E7
- Isotyp
- IgG2b kappa
- Top Product
- Discover our top product MET Primärantikörper
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- Applikationshinweise
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Flow cytometry: 1.2 µg/10^6 cells
CELISA: 1:200 - 1:400
For each application a titration should be performed to determine the optimal concentration. - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Buffer
- PBS, pH 7.2
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- 4 °C
- Informationen zur Lagerung
- short term: 2 °C - 8 °C, long term: -20 °C
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- Target
- c-MET (MET) (Met Proto-Oncogene (MET))
- Andere Bezeichnung
- c-Met (MET Produkte)
- Hintergrund
- C-MET is a receptor tyrosine kinase that is activated upon Hepatocyte Growth Factor (HGF) binding. c-MET is produced as a single-chain precursor and plays en essential role in embryonic development and wound healing. It belongs to the class of Single-pass type I membrane proteins and it is normally expressed by cells of epithelial origin while the expression of HGF is restricted to cells of mesenchymal origin in an almost perfect paracrine paradigm. Overexpression of c-MET can be found in several kinds of tumor progression.
- UniProt
- P08581
- Pathways
- RTK Signalweg, Carbohydrate Homeostasis, Synaptic Membrane, Signaling of Hepatocyte Growth Factor Receptor
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