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E2F1 Antikörper (E2F Transcription Factor 1) pSer364 Primary Antibody

E2F1 Reaktivität: Human IHC, ELISA, WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN129619
$658.50
Zzgl. Versandkosten $45.00 und $20.00 Trockeneis
100 μg
local_shipping Lieferung nach: Vereinigte Staaten von Amerika
Lieferung in 1 bis 2 Werktagen
  • Target Alle E2F1 Antikörper anzeigen
    E2F1
    Bindungsspezifität
    • 27
    • 26
    • 22
    • 20
    • 15
    • 15
    • 13
    • 11
    • 10
    • 10
    • 9
    • 9
    • 8
    • 8
    • 7
    • 7
    • 6
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 360-369, pSer364
    Reaktivität
    • 241
    • 110
    • 59
    • 7
    • 6
    • 6
    • 5
    • 5
    • 5
    • 3
    • 3
    • 3
    • 1
    • 1
    Human
    Wirt
    • 229
    • 21
    • 14
    Kaninchen
    Klonalität
    • 234
    • 30
    Polyklonal
    Konjugat
    • 109
    • 21
    • 19
    • 18
    • 12
    • 9
    • 9
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 5
    • 5
    • 5
    • 5
    • 5
    Dieser E2F1 Antikörper ist unkonjugiert
    Applikation
    • 159
    • 121
    • 67
    • 66
    • 55
    • 32
    • 31
    • 29
    • 24
    • 23
    • 17
    • 13
    • 7
    • 2
    • 1
    • 1
    Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
    Kreuzreaktivität
    Schimpanse
    Produktmerkmale
    Concentration Definition: by UV absorbance at 280 nm
    Immunogen
    This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to amino acids 360-369 of Human E2F-1.
    Isotyp
    IgG
  • Applikationshinweise
    This affinity purified antibody has been tested for use in ELISA, immunohistochemistry and by western blot.  Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 47 kDa in size corresponding to phosphorylated E2F-1 by western blotting in the appropriate cell lysate or extract.  Less than 0.5% reactivity is observed against the non-phosphorylated form of the immunizing peptide.  This antibody is phospho specific for pS364 of E2F-1.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.80 mg/mL
    Buffer
    0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
  • Target
    E2F1
    Andere Bezeichnung
    E2F-1 (E2F1 Produkte)
    Synonyme
    CG6376, DRTF1/E2F, DmE2F-1, Dmel\\CG6376, Dp, E(Sev-CycE)3A, E(var)3-93E, E(var)3-95E, E(var)93E, E2F, E2F-1, E2F1, E2f1, Evar(3)164, dE2F, dE2F1, dE2f, dE2f1, de2f1, def21, drosE2F1, e2f, e2f1, l(3)07172, l(3)j3B1, l(3)j3C2, l(3)rM729, RBAP1, RBBP3, RBP3, mKIAA4009, xE2F, ATE2FB, E2F TRANSCRIPTION FACTOR-1 E2F1, E2F transcription factor 1, E2FB, E2FB TRANSCRIPTION FACTOR, E2F transcription factor 1, E2F transcription factor 1 L homeolog, E2f1, E2F1, e2f1.L
    Hintergrund
    E2F-1 (also known as tran-scription factor E2F-1, Retinoblastoma binding protein 3, RBBP-3, PRB-binding protein E2F-1, PBR3, Retinoblastoma-associated protein 1 and RBAP-1) is a transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3'.  The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several domains con-served through evolution that are found in most members of the family. These domains include a DNA binding domain, a dimerization domain that
    Synonyms: E2F 1 antibody, E2F transcription factor 1 antibody, E2F-1 antibody, E2f1 E2F transcription factor 1 antibody, KIAA4009 antibody, mKIAA4009 antibody, OTTHUMP00000030661 antibody, PBR 3 antibody, PBR3 antibody
    Gen-ID
    1869, 12669911
    UniProt
    Q01094
    Pathways
    p53 Signalweg, Zellzyklus, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Autophagie
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