Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

PLK1 Antikörper (pThr210)

Der Kaninchen Polyklonal Anti-PLK1-Antikörper wurde für WB, ELISA und IHC validiert. Er ist geeignet, PLK1 in Proben von Human und Maus zu detektieren. Es ist 1 Publikation verfügbar.
Rockland
Produktnummer ABIN129581
Hersteller Produkt- Nr.: 600-401-446

Kurzübersicht für PLK1 Antikörper (pThr210) (ABIN129581)

Target

Alle PLK1 Antikörper anzeigen
PLK1 (Polo-Like Kinase 1 (PLK1))

Reaktivität

  • 128
  • 49
  • 39
  • 7
  • 7
  • 6
  • 5
  • 5
  • 5
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
Human, Maus

Wirt

  • 98
  • 28
  • 2
  • 2
Kaninchen

Klonalität

  • 102
  • 28
Polyklonal

Konjugat

  • 78
  • 5
  • 5
  • 4
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
Dieser PLK1 Antikörper ist unkonjugiert

Applikation

  • 101
  • 48
  • 32
  • 28
  • 27
  • 19
  • 19
  • 16
  • 7
  • 6
  • 4
  • 4
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
  • Bindungsspezifität

    • 22
    • 21
    • 15
    • 12
    • 8
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pThr210

    Hersteller Produkt- Nr.

    600-401-446

    Hersteller

    Rockland

    Verwendungszweck

    PLK1 phospho T210 Antibody

    Kreuzreaktivität (Details)

    Anti-Polo-like Kinase pT210 Antibody is directed against human phosphorylated Plk1 protein.

    Produktmerkmale

    Synonyms: rabbit anti-PLK1 pT210 antibody, Serine/threonine-protein kinase PLK1, rabbit anti-polio like kinase 1 antibody, Serine/threonine protein kinase 13 antibody, PLK-1, PLK 1, STPK13

    Aufreinigung

    This antibody was affinity purified.

    Sterilität

    Sterile filtered

    Immunogen

    Immunogen: Anti-Polo-like Kinase pT210 Antibody was produced by repeated immunizations with a synthetic phospho peptide corresponding to an internal region near aa 200-225 of Human Polo-like kinase 1 (Plk1) protein.

    Immunogen Type: Conjugated Peptide

    Isotyp

    IgG
  • Applikationshinweise

    Immunohistochemistry Dilution: 1:200 - 1:1,000

    Application Note: This affinity-purified antibody has been tested for use in ELISA, IHC, and by western blot.  Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 68 kDa in size corresponding to Plk-1 by western blotting in the appropriate cell lysate or extract.   This antibody is positive by IHC on kidney, liver, cancer, thyroid and lymphocyte tissue.

    Western Blot Dilution: 1:200 - 1:2,000

    ELISA Dilution: 1:3,000 - 1:12,000

    Other: User Optimized

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1.0 mg/mL

    Buffer

    Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

    Stabilizer: None

    Preservative: 0.01 % (w/v) Sodium Azide

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

    Haltbarkeit

    12 months
  • Adler, Müller, Rached, Dekant, Mally: "Modulation of key regulators of mitosis linked to chromosomal instability is an early event in ochratoxin A carcinogenicity." in: Carcinogenesis, Vol. 30, Issue 4, pp. 711-9, (2009) (PubMed).

  • Target

    PLK1 (Polo-Like Kinase 1 (PLK1))

    Andere Bezeichnung

    PLK1

    Hintergrund

    Background: Polo-like Kinase pT210 Antibody detects phosphorylated Plk1 protein. Polo-like kinase 1, also known as Plk-1, serine-threonine protein kinase 13 and STPK13, may be required for cell division and have a role during G1 or S phase and is associated with the phosphorylation of cyclin B1.  Phosphorylation of Plk-1 on T210 contributes to proper mitotic progression.  Plk-1 has a nuclear localization and accumulates to a maximum during the G2 and M phases, declines to a nearly undetectable level following mitosis and throughout G1 phase, and then begins to accumulate again during S phase.  Plk-1 is a member of the Ser/Thr protein kinase family and the CDC5/Polo subfamily and contains 2 POLO box domains.

    Gen-ID

    5347, 21359873

    UniProt

    P53350

    Pathways

    Zellzyklus, M Phase
Sie sind hier:
Chat with us!