NAIP Antikörper

Produktnummer ABIN127053

Der Kaninchen Polyklonal anti-NAIP Antikörper (ABIN127053) detektiert spezifisch NAIP in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für NAIP Antikörper (ABIN127053)

Target: NAIP (NLR Family, Apoptosis Inhibitory Protein (NAIP))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NAIP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-NAIP Antikörper

Spezifität: This antibody detects NAIP.

Aufreinigung: Affinity purified

Immunogen: Synthetic peptide surrounding amino acid 506 of human NAIP.

Anwendungsinformationen

Applikationshinweise: Western Blot: 1 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.2 mg/mL

Buffer: PBS, pH 7.2, containing 50 % glycerol, 1 % BSA, 0.02 % thimerosal

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C/-80 °C

Informationen zur Lagerung: Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -70 °C.

Details zu NAIP

Target: NAIP (NLR Family, Apoptosis Inhibitory Protein (NAIP))

Andere Bezeichnung: NAIP

Hintergrund: NAIP (neuronal apoptosis inhibitor protein) is a member of the IAPs (inhibitor of apoptosis proteins) that function in cell death pathways to inhibit apoptosis. NAIP was discovered based on its association with a neurodegenerative disorder. Mutations and deletions in the NAIP gene locus is a contributing factor in spinal muscular atrophy. Coexpression of NAIP and hippocalcin protects neurons against calcium-induced cell death. NAIP is strongly expressed in anterior horn and motor cortex neurons of the normal brain. It is also found in human fetal neurons and in adult choroid plexus cells.Synonyms: BIRC1, Baculoviral IAP repeat-containing protein 1

Gen-ID: 100510692

NCBI Accession: NP_004527

UniProt: Q13075

Pathways: Apoptose, Inflammasome