Caspase 6 Antikörper (active, C-Term)

Produktnummer ABIN127030

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch Caspase 6 in WB. Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.

Kurzübersicht für Caspase 6 Antikörper (active, C-Term) (ABIN127030)

Target: Caspase 6 (CASP6) (Caspase 6, Apoptosis-Related Cysteine Peptidase (CASP6))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Caspase 6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Caspase 6 Antikörper

Bindungsspezifität: active, C-Term

Spezifität: The antibody detects the large subunit (18 kDa) of the active caspase-6. The antibody does not recognize other caspases.

Aufreinigung: Affinity purified

Immunogen: Synthetic peptide surrounding amino acids mapping to the Cterminus of the large fragment of human caspase-6.

Anwendungsinformationen

Applikationshinweise: Western Blot: 0.5-4 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: PBS, pH 7.2, containing 30 % glycerol, 0.5 % BSA, 0.01 % thimerosal

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C/-80 °C

Informationen zur Lagerung: Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -70 °C.

Details zu Caspase 6

Target: Caspase 6 (CASP6) (Caspase 6, Apoptosis-Related Cysteine Peptidase (CASP6))

Andere Bezeichnung: Caspase-6

Hintergrund: Caspase family of cysteine proteases has been shown to play a key role in apoptosis. Similar to other caspases, caspase-6 is also synthesized as an inactive pro-enzyme that is processed in cells undergoing apoptosis. Together with caspase-3, caspase-6 is one of the major caspases in apoptotic cells, and functions downstream of apoptosis inhibitors Bcl-2 and Bcl-xL. Caspase-6 has also been shown involving in the proteolysis of poly (ADP-ribose) polymerase (PARP) and nuclear lamin A.Synonyms: Apoptotic protease Mch-2, CASP-6, CASP6, MCH-2, MCH2

Gen-ID: 839

NCBI Accession: NP_001217

UniProt: P55212

Pathways: Apoptose, Caspase Kaskade in der Apoptose