BAX Antikörper (N-Term)
Kurzübersicht für BAX Antikörper (N-Term) (ABIN126979)
Target
Alle BAX Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
 - N-Term
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Spezifität
 - The antibody detects a 20 kDa protein, corresponding to the apparent molecular weight of Bax on SDS-PAGE Immunoblots.
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Aufreinigung
 - Affinity Chromatography
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Immunogen
 - Synthetic peptide corresponding to amino acids near the N-terminus of Human Bax
 
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Applikationshinweise
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                        Western BLot: 0.5-4 μg/mL. Immunoprecipitation: 10-20 μg/mL. Rat kidney tissue lysate can be used as a positive control. 
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 
                                            
Beschränkungen
 - Nur für Forschungszwecke einsetzbar
 
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Konzentration
 - 0.5 mg/mL
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Buffer
 - PBS, pH 7.2, containing 30 % Glycerol, 0.5 % BSA and 0.01 % Thimerosal.
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Konservierungsmittel
 - Thimerosal (Merthiolate)
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Vorsichtsmaßnahmen
 - This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
 - Avoid repeated freezing and thawing.
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Lagerung
 - -20 °C/-80 °C
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Informationen zur Lagerung
 - Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -70 °C.
 
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- BAX (BCL2-Associated X Protein (BAX))
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Andere Bezeichnung
 - Bax
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Hintergrund
 - The Bcl-2 (B-cell leukemia/lymphoma 2) family proteins function to either inhibit (Bcl-2 and Bcl-XL) or promote (Bax and Bak) apoptosis. Bax contains the conserved Bcl-2 homology 1 (BH1) and 2 (BH2) domains that allow for its homodimerization or heterodimerization with Bcl-2. When Bcl-2 is in excess, apoptosis is inhibited. However, if Bax levels increase in response to a death signal, the cell is pushed toward death.Synonyms: Apoptosis regulator BAX, BCL2-associated X protein, BCL2L4, Bcl-2-like protein 4, Bcl2-L-4
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Gen-ID
 - 9606
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UniProt
 - Q07812
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Pathways
 - p53 Signalweg, PI3K-Akt Signalweg, Apoptose, Caspase Kaskade in der Apoptose, Positive Regulation of Endopeptidase Activity, Unfolded Protein Response
 
Target
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