IFNA Antikörper

Produktnummer ABIN121866

Der Kaninchen Polyklonal anti-IFNA Antikörper (ABIN121866) detektiert spezifisch IFNA in WB, IP, Func und EIA. Dieser Antikörper reagiert spezifisch mit Proben aus Huhn.

Kurzübersicht für IFNA Antikörper (ABIN121866)

Target: IFNA (Interferon alpha (IFNA))

Reaktivität: Huhn

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IFNA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP), Functional Studies (Func), Enzyme Immunoassay (EIA)

Produktdetails anti-IFNA Antikörper

Aufreinigung: Affinity chromatography on protein G

Immunogen: Recombinant chicken Interferon alpha

Anwendungsinformationen

Applikationshinweise: ELISA. Western Blot: This antibody cross reacts with IFN beta in western blots but does not show any cross reactivity with IFN gamma, this antibdoy detects a band of approximately 19 kDa. Functional Assays. Immunoprecipitation.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: PBS

Konservierungsmittel: Azide free

Lagerung: -20 °C

Informationen zur Lagerung: Store the antibody at -20 °C. Avoid repeated freezing and thawing.
Shelf Life: one year from despatch.

Haltbarkeit: 12 months

Details zu IFNA

Target: IFNA (Interferon alpha (IFNA))

Andere Bezeichnung: Interferon alpha (IFN Alpha)

Hintergrund: The classification of mammalian cytokines with antiviral activity, is well documented as being either Type I Interferon (IFNI) or Type II Interferon (IFNII). This is not the case for avian IFNs however, even though IFN was first detected in the chicken. A growing number of functional studies indicate similarities between chicken IFN and mammalian IFNI, revealing the conservation of cysteine residues and the existence of around ten closely related intron-less IFN alpha genes. Further research has shown that chIFN-alpha genes are strongly expressed following viral infection of monocyte-derived macrophage and embryo fibroblasts and that recombinant chicken IFN acts as a potent antiviral agent.Synonyms: B Cell Interferon, IFN-alpha, IFNA, Interferon-alpha, Leukocyte Interferon, Type I Interferon

Pathways: JAK-STAT Signalweg, TLR Signalweg, Hepatitis C, Inflammasome