Growth Hormone 1 Antikörper

Produktnummer ABIN121163

Produktdetails anti-Growth Hormone 1 Antikörper

Target: Growth Hormone 1 (GH1)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Growth Hormone 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Spezifität: The antibody recognizes human Growth Hormone (hGH). Other species not tested.

Aufreinigung: Protein-G affinity chromatography

Immunogen: Recombinant human Growth Hormone protein

Klon: G3H5

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: ELISA. Western blot (1:500 - 1:1,000).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.0 mg/mL

Buffer: PBS, pH 7.4, containing 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf Life: one year from despatch.

Haltbarkeit: 12 months

Details zu Growth Hormone 1

Target: Growth Hormone 1 (GH1)

Andere Bezeichnung: Somatotropin / Growth Hormone / GH1 (GH1 Produkte)

Synonyme: GH antikoerper, GH-N antikoerper, GHN antikoerper, IGHD1B antikoerper, hGH-N antikoerper, Gh1 antikoerper, GH1 antikoerper, gh antikoerper, Gh antikoerper, GH2 antikoerper, RNGHGP antikoerper, ghl antikoerper, gh-n antikoerper, ghn antikoerper, ighd1b antikoerper, gh1 antikoerper, ghb-A antikoerper, GHI antikoerper, GHB3 antikoerper, growth hormone 1 antikoerper, growth hormone antikoerper, somatotropin-like antikoerper, somatotropin antikoerper, growth hormone prepeptide antikoerper, growth hormone 1 L homeolog antikoerper, growth hormone 1 S homeolog antikoerper, Somatotropin-1 antikoerper, GH1 antikoerper, Gh antikoerper, GH antikoerper, LOC100305005 antikoerper, Gh1 antikoerper, LOC100534452 antikoerper, LOC100232594 antikoerper, LOC100303681 antikoerper, gh1 antikoerper, LOC100356068 antikoerper, LOC100136588 antikoerper, gh1.L antikoerper, gh1.S antikoerper, LOC109081196 antikoerper

Hintergrund: Human growth hormone(hGH, somatotropin), a protein hormone from the anterior lobe of the pituitary gland, comprises a single polypeptide chain of 191 amino acid residues. The 20KDa variant form of human growth hormone (20KDa hGH) presents in extracts from pituitary glands and it differs from the major form of hGH (22KDa, 191 amino acid) by the deletion of amino acid residues 32-46. The growth hormone amino acid sequence varies considerably between species, and non-primate growth hormones have little activity in man. Main functions of hGH and 20KDa hGH are the stimulation of somatic and bone growth, as well as an increase in the size and mass of organs and tissues. The gene, along with four other related genes, is located at the growth hormone locus on chromosome 17 where they are interspersed in the same transcriptional orientation, an arrangement which is thought to have evolved by a series of gene duplications. The five genes share a remarkably high degree of sequence identity. Alternative splicing generates additional isoforms of each of the five growth hormones, leading to further diversity and potential for specialization. Mutations in or deletions of the gene lead to growth hormone deficiency and short stature.Synonyms: Growth hormone 1, HGH, Pituitary growth hormone

Gen-ID: 2688

UniProt: P01241

Pathways: NF-kappaB Signalweg, JAK-STAT Signalweg, Intracellular Steroid Hormone Receptor Signaling Pathway, Peptide Hormone Metabolism, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Hormone Metabolic Process, Response to Growth Hormone Stimulus, Regulation of Hormone Biosynthetic Process