IFNA Antikörper

Produktnummer ABIN120183

Der Maus Monoklonal anti-IFNA Antikörper (Klon UMCh3-IFN-a) (ABIN120183) detektiert spezifisch IFNA in WB und EIA. Dieser Antikörper reagiert spezifisch mit Proben aus Huhn.

Kurzübersicht für IFNA Antikörper (ABIN120183)

Target: IFNA (Interferon alpha (IFNA))

Reaktivität: Huhn

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser IFNA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Klon: UMCh3-IFN-a

Produktdetails anti-IFNA Antikörper

Aufreinigung: Affinity chromatography on Protein G

Immunogen: Recombinant chicken Interferon alpha.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA. Western Blot: this antibody detects a band of approximately 19 kDa.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: PBS containing 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu IFNA

Target: IFNA (Interferon alpha (IFNA))

Andere Bezeichnung: Interferon alpha (IFN Alpha)

Hintergrund: The classification of mammalian cytokines with antiviral activity, is well documented as being either Type I Interferon (IFNI) or Type II Interferon (IFNII). This is not the case for avian IFNs however, even though IFN was first detected in the chicken. A growing number of functional studies indicate similarities between chicken IFN and mammalian IFNI, revealing the conservation of cysteine residues and the existence of around ten closely related intron-less IFN alpha genes. Further research has shown that chIFN-alpha genes are strongly expressed following viral infection of monocyte-derived macrophage and embryo fibroblasts and that recombinant chicken IFN acts as a potent antiviral agent.Synonyms: B Cell Interferon, IFN-alpha, IFNA, Interferon-alpha, Leukocyte Interferon, Type I Interferon

Pathways: JAK-STAT Signalweg, TLR Signalweg, Hepatitis C, Inflammasome