c-MYC Antikörper (C-Term) (HRP)

Produktnummer ABIN119683

Dieser Maus Monoklonal Antikörper detektiert spezifisch c-MYC in WB, IHC (p), IHC (fro) und EIA. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für c-MYC Antikörper (C-Term) (HRP) (ABIN119683)

Target: c-MYC (MYC) (Myc Proto-Oncogene protein (MYC))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser c-MYC Antikörper ist konjugiert mit HRP

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA)

Klon: 9-00E-010

Produktdetails anti-c-MYC Antikörper (HRP)

Bindungsspezifität: C-Term

Sequenz: AEEQKLISEE DLL

Spezifität: This antibody detects the 62 kDa c-myc gene product. SM1863HRP may also be used to detect the commonly used c-myc 'tag'.

Kreuzreaktivität (Details): Species reactivity (tested):Human.

Aufreinigung: Affinity Chromatography on Protein G

Immunogen: Synthetic peptide sequence corresponding to the C-terminal region of Human c-myc.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: 1/100-1/500. Western blot: 1/100-1/500 (Non-Reducing Conditions). Detects a band of approximately 62 kDa in Colo 320HSR cell lysates. Immunohistochemistry on Frozen and Paraffin Sections: This product does not requireprotein digestion pre-treatment of paraffin sections prior to staining and does not requireantigen retrieval using heat treatment prior to staining of paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS, pH 7.4, 0.01 % Thimerosal, HRP Stabilizer

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu c-MYC

Target: c-MYC (MYC) (Myc Proto-Oncogene protein (MYC))

Andere Bezeichnung: C-Myc

Hintergrund: C-myc gene product is involved in the regulation of the cell cycle and cell growth. It is primarily located to the cell nucleus, but has also been shown to localised to the cytoplasm in several cell lines. Overexpression of c-myc has been reported in a wide variety of human cancers.Synonyms: c-myc tag, myc tag, myc-tag

Gen-ID: 4609

NCBI Accession: NP_002458

UniProt: P01106

Pathways: p53 Signalweg, Zellzyklus, Sensory Perception of Sound, Transition Metal Ion Homeostasis, Mitotic G1-G1/S Phases, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus, Warburg Effekt