CTLA4 Antikörper

Produktnummer ABIN119631

Der Maus Monoklonal anti-CTLA4 Antikörper (Klon WKH203) (ABIN119631) detektiert spezifisch CTLA4 in WB, FACS, IHC (fro) und EIA. Dieser Antikörper reagiert spezifisch mit Proben aus Ratte.

Kurzübersicht für CTLA4 Antikörper (ABIN119631)

Target: CTLA4 (Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))

Reaktivität: Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CTLA4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA)

Klon: WKH203

Produktdetails anti-CTLA4 Antikörper

Spezifität: This antibody recognises CD152, also known as cytotoxic-T-lymphocyte antigen-4 (CTLA-4).

Aufreinigung: Affinity chromatography on Protein G

Immunogen: Purified rCTLA-4hIg fusion protein. Spleen cells from immunised Balb/c were fused with cells of the X63-Ag8-653 myeloma cell line.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Flow cytometry: 1:10 - 1:20, use 10 μL to label 10^6 cells in 100 μL, membrane permeabilisation is required for this application. ELISA. Western blot.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS containing 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu CTLA4

Target: CTLA4 (Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))

Andere Bezeichnung: CD152 / CTLA4

Hintergrund: CD152 is similar in structure to CD28 and also binds ligands CD80 and CD86. CD152 is expressed by activated T-lymphocytes. Studies suggest that CD152 is also expressed by regulatory T-lymphocytes.Synonyms: CTLA-4, Cytotoxic T-lymphocyte protein 4, Cytotoxic T-lymphocyte-associated antigen 4

Gen-ID: 63835

NCBI Accession: NP_113862

UniProt: Q62859

Pathways: Cancer Immune Checkpoints