Leptin Antikörper (Biotin)
Kurzübersicht für Leptin Antikörper (Biotin) (ABIN1169153)
Target
Alle Leptin (LEP) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Verwendungszweck
- anti-Leptin (rat), pAb (Biotin)
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Spezifität
- Recognizes rat leptin. Weakly cross-reacts with human and mouse leptin. Detects a band of ~16 kDa by Western blot.
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Kreuzreaktivität (Details)
- Weakly cross-reacts with human and mouse leptin.
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Produktmerkmale
- Polyclonal Antibody. Recognizes rat leptin. Weakly cross-reacts with human and mouse leptin. Detects a band of ~16 kDa by Western blot. Source: Rabbit. Applications: ELISA, WB. Liquid. 0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives. Leptin is involved in the signaling pathway that regulates the size of the body fat depot. An increase in the level of leptin may act directly or indirectly on the CNS to inhibit food intake and/or regulate energy expenditure as part of a homeostatic mechanism to maintain constancy of the adipose mass. Defects in the leptin gene may be a cause of autosomal recessive obesity.
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Sterilität
- 0.2 μm filtered
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Immunogen
- Recombinant rat leptin.
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- 0.2μm-filtered solution in PBS, pH 7.4.
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Konservierungsmittel
- Without preservative
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Handhabung
- After opening, prepare aliquots and store at -20 °C.Avoid freeze/thaw cycles.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
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+4°C
-20°C
Stable for at least 6 months after receipt when stored at -20°C.
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Haltbarkeit
- 6 months
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- Leptin (LEP)
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Andere Bezeichnung
- Leptin
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Hintergrund
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Alternate Names/Synonyms: OB Gene Product, Obese Factor
Product Description: Leptin is involved in the signaling pathway that regulates the size of the body fat depot. An increase in the level of leptin may act directly or indirectly on the CNS to inhibit food intake and/or regulate energy expenditure as part of a homeostatic mechanism to maintain constancy of the adipose mass. Defects in the leptin gene may be a cause of autosomal recessive obesity.
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UniProt
- P50596
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Pathways
- JAK-STAT Signalweg, AMPK Signaling, Hormone Transport, Peptide Hormone Metabolism, Hormone Activity, Negative Regulation of Hormone Secretion, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour, Monocarboxylic Acid Catabolic Process
Target
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