CDK1 Antikörper

Produktnummer ABIN114583

Dieser Maus Monoklonal Antikörper detektiert spezifisch CDK1 in WB, IF, IP und IHC (p). Es zeigt Reaktivität gegenüber Proben von Human und Rind (Kuh).Es wurde in 1 Publikation zitiert.

Kurzübersicht für CDK1 Antikörper (ABIN114583)

Target: CDK1 (Cyclin-Dependent Kinase 1 (CDK1))

Reaktivität: Human, Rind (Kuh)

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CDK1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: POH-1

Produktdetails anti-CDK1 Antikörper

Spezifität: The antibody POH-1 specifically detects Cdk1 (p34Cdc2). Staining of Cdk1 reflects the proliferating potential of respective tissue.

Kreuzreaktivität (Details): Species reactivity (tested):Human, Non-Human Primates, Bovine.

Aufreinigung: Affinity Chromatography on Protein A.

Immunogen: Recombinant human cdc2 protein.

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Western Blot. Immunoprecipitation. Immunocytochemistry. Immunohistochemistry on Paraffin Sections: 10 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS, pH ~7.4, 15 mM Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Referenzen für anti-CDK1 Antikörper (ABIN114583)

Jaeger, Koczan, Thiesen, Ibrahim, Gross, Spang, Kunz: "Gene expression signatures for tumor progression, tumor subtype, and tumor thickness in laser-microdissected melanoma tissues." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 13, Issue 3, pp. 806-15, (2007) (PubMed).

Details zu CDK1

Target: CDK1 (Cyclin-Dependent Kinase 1 (CDK1))

Andere Bezeichnung: CDK1

Hintergrund: The p34cdc2 is a 34 kDa phosphoprotein with protein kinase activity that functions in the G2/M phase transition of the cell cycle. Expression of p34cdc2 reflects the proliferating potential of positively staining tissue. The maximal activity of p34cdc2 is achieved when it is fully dephosphorylated. It is a 34kD catalytic subunit of maturation promoting factor (MPF) and complexes with both cyclin A and cyclin B in mammalian cells.Synonyms: CDC2, CDC28A, CDK1, CDKN1, Cell division control protein 2 homolog, Cell division protein kinase 1, Cyclin-dependent kinase 1, P34CDC2, p34 protein kinase

Gen-ID: 983

NCBI Accession: NP_001777

UniProt: P06493

Pathways: Zellzyklus, Fc-epsilon Rezeptor Signalübertragung, Neurotrophin Signalübertragung, Activation of Innate immune Response, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Toll-Like Receptors Cascades, Synthesis of DNA