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PCNA Antikörper
PCNA
Reaktivität: Human, Maus, Ratte
WB, IF, IHC (p), IHC (fro)
Wirt: Maus
Monoclonal
IML-83
unconjugated
Produktnummer ABIN1108598
Produktdetails anti-PCNA Antikörper
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Target
Alle PCNA Antikörper anzeigen
PCNA
(Proliferating Cell Nuclear Antigen (PCNA))
Reaktivität
Alle Reaktivitäten für PCNA Antikörper
Human, Maus, Ratte
Wirt
Alle Wirte für PCNA Antikörper
Maus
Klonalität
Alle Klonalitäten für PCNA Antikörper
Monoklonal
Konjugat
Alle Konjugate für PCNA Antikörper
Dieser PCNA Antikörper ist unkonjugiert
Applikation
Alle Applikationen für PCNA Antikörper
Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
Spezifität
This antibody reacts to PCNA.
Aufreinigung
Affinity chromatography
Immunogen
Protein A fusion protein
Klon
IML-83
Isotyp
IgG2a
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Anwendungsinformationen
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Applikationshinweise
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Rekonstitution
Restore with 1.2 % sodium acetate or neutral PBS
Konzentration
0,1 mg/mL
Buffer
1.2 % sodium acetate, with 2 mg BSA and 0.01 mg sodium azide as preservative.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
Avoid repeated freezing and thawing.
Lagerung
-20 °C
Informationen zur Lagerung
Prior to reconstitution store at -20 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Details zu PCNA
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Target
PCNA
(Proliferating Cell Nuclear Antigen (PCNA))
Andere Bezeichnung
PCNA (PCNA Produkte )
Hintergrund
Proliferating cell nuclear antigen (PCNA) was originally identified by immunofluorescence as a nuclear protein whose appearance correlated with the proliferative state of the cell. PCNA /cyclin has been localized by in situ hybridization to the short arm of human chromosome 20 with a peak of grains over band 20p13. PCNA gene is present in single copy and has 6 exons. It spans 4,961 bp. Synthesis of the nuclear protein cyclin and DNA in quiescent mouse fibroblasts is coordinately induced by serum and purified growth factors. PCNA controls establishment of sister chromatid cohesion during S phase.Synonyms: Cyclin, Proliferating Cell Nuclear Antigen
Gen-ID
5111
NCBI Accession
NP_002583
UniProt
P12004
Pathways
Telomere Maintenance , DNA Reparatur , Mitotic G1-G1/S Phases , DNA Replication , Synthesis of DNA , Autophagie
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