Paxillin Antikörper (C-Term)

Produktnummer ABIN1108595

Der Maus Monoklonal anti-Paxillin Antikörper wird verwendet zum Nachweis von Paxillin in Proben von Human, Maus, Ratte und Huhn. Er wurde validiert für WB und IF.

Kurzübersicht für Paxillin Antikörper (C-Term) (ABIN1108595)

Target: Paxillin (PXN)

Reaktivität: Human, Maus, Ratte, Huhn

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Paxillin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Klon: PAX-14

Produktdetails anti-Paxillin Antikörper

Bindungsspezifität: AA 305-559, C-Term

Spezifität: This antibody reacts to Paxillin.

Aufreinigung: Affinity chromatography

Immunogen: C-terminal part of recombinant chicken paxillin (amino acids 305-559)

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: Restore with 1.2 % sodium acetate or neutral PBS

Konzentration: 0,1 mg/mL

Buffer: 1.2 % sodium acetate, with 2 mg BSA and 0.01 mg sodium azide as preservative.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Prior to reconstitution store at -20 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu Paxillin

Target: Paxillin (PXN)

Andere Bezeichnung: Paxillin / PXN

Hintergrund: The paxillin gene can be alternatively spliced to include 1 of 2 alternative exons, generating beta and gamma isoforms. Paxillin is a 68- kDa focal adhesion protein that is phosphorylated on tyrosine residues in fibroblasts in response to transformation by v-src, treatment with platelet-derived growth factor, or cross-linking of integrins. The 68-kD protein (paxillin) is a cytoskeletal component that localizes to the focal adhesions at the ends of actin stress fibers in chicken embryo fibroblasts. It is also present in the focal adhesions of Madin-Darby bovine kidney (MDBK) epithelial cells but is absent, like talin, from the cell-cell adherens junctions of these cells.Synonyms: FLJ16691

Gen-ID: 5829

NCBI Accession: NP_001074324

UniProt: P49023

Pathways: MAPK Signalweg, EGFR Signaling Pathway, Response to Growth Hormone Stimulus, Cell-Cell Junction Organization, Maintenance of Protein Location, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, VEGF Signaling