CDK2 Antikörper

Produktnummer ABIN1106646

Der Maus Monoklonal anti-CDK2 Antikörper (Klon 8A12) (ABIN1106646) detektiert spezifisch CDK2 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für CDK2 Antikörper (ABIN1106646)

Target: CDK2 (Cyclin-Dependent Kinase 2 (CDK2))

Reaktivität: Human, Maus, Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CDK2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: 8A12

Produktdetails anti-CDK2 Antikörper

Spezifität: This antibody recognizes human Cdk2 and human Cdk5 and does not recognize human Cdc2 (Cdk1) on Western blot.

Kreuzreaktivität (Details): Species reactivity (tested):Human, mouse, rat

Aufreinigung: Protein A agarose

Immunogen: Recombinant human Cdk2

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: Prepare a stock solution by dissolving the lyophilized antibody 100 μL of distilled water. After reconstitution, the IgG concentration should be 1 mg/mL.

Buffer: PBS ( pH 7.2) containing 1 % sucrose, 0.09 % NaN3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Prior to reconstitution store at 2-8 °C. Following reconstitution store (in aliquots) at -20 °C.

Details zu CDK2

Target: CDK2 (Cyclin-Dependent Kinase 2 (CDK2))

Andere Bezeichnung: CDK2

Hintergrund: Cellular proliferation is controlled by a family of protein kinases in which the catalytic subunits are members of the cyclin-dependent kinase (cdk) family and the regulatory subunits are cyclins. To date, nine distinct Cdks in addition to eight different cyclins have been identified, in which different CDK/cyclin combinations serve to regulate distinct points in the mammalian cell division cycle. Although Cdc2Hs (Cdk1)/cyclin B controls the transition of cells from the G2 to M-phase, the activities of Cdk2/cyclin E and Cdk2/cyclin A are critical for G1/S-phase transition and progression through S-phase.Synonyms: Cell division protein kinase 2, Cyclin dependent kinase 2, p33 protein kinase

Gen-ID: 1017

NCBI Accession: NP_001789

UniProt: P24941

Pathways: PI3K-Akt Signalweg, Zellzyklus, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Synthesis of DNA