CD25 Antikörper

Produktnummer ABIN1106136

Dieser Anti-CD25-Antikörper ist ein Maus-Monoklonal-Antikörper zum Nachweis von CD25 in FACS. Geeignet für Human.

Kurzübersicht für CD25 Antikörper (ABIN1106136)

Target: CD25 (IL2RA) (Interleukin 2 Receptor, alpha (IL2RA))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD25 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS)

Klon: B-G3

Produktdetails anti-CD25 Antikörper

Spezifität: Recognises both soluble and membrane bound Interleukin 2 Receptor a chain (IL-2 Ra), a 55 kDa protein.

Aufreinigung: Ion exchange chromatography

Sterilität: 0.22 μm filtered

Immunogen: PHA activated T cells

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1,0 mg/mL

Buffer: Phosphate-buffered saline. Sterile-filtered through 0.22 μm. Carrier and preservative free

Konservierungsmittel: Without preservative

Lagerung: 4 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C.

Details zu CD25

Target: CD25 (IL2RA) (Interleukin 2 Receptor, alpha (IL2RA))

Andere Bezeichnung: CD25 / IL2RA

Hintergrund: Genetic variations in IL2RA are associated with susceptibility to diabetes mellitus insulin-dependent type 10 (IDDM10) [MIM:601942]. A multifactorial disorder of glucose homeostasis that is characterized by susceptibility to ketoacidosis in the absence of insulin therapy. Clinical fetaures are polydipsia, polyphagia and polyuria which result from hyperglycemia-induced osmotic diuresis and secondary thirst. These derangements result in long-term complications that affect the eyes, kidneys, nerves, and blood vessels.Synonyms: IL-2 receptor alpha subunit, IL-2-RA, IL2-RA, Interleukin-2 receptor alpha chain, TAC antigen, p55

Gen-ID: 3559

NCBI Accession: NP_000408

UniProt: P01589

Pathways: JAK-STAT Signalweg, Growth Factor Binding, Activated T Cell Proliferation