PLK1 Antikörper (AA 331-508)
Kurzübersicht für PLK1 Antikörper (AA 331-508) (ABIN1098105)
Target
Alle PLK1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 331-508
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Verwendungszweck
- PLK1 Antibody
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Aufreinigung
- Purified antibody
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Immunogen
- Purified recombinant fragment of human PLK1 (AA: 331-508) expressed in E. Coli.
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Isotyp
- IgG1
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Applikationshinweise
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ELISA: 1/10000
FCM: 1/200 - 1/400
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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Suppression of Polo like kinase 1 (PLK1) by p21(Waf1) mediates the p53-dependent prevention of caspase-independent mitotic death." in: Cellular signalling, Vol. 23, Issue 11, pp. 1816-23, (2011) (PubMed).
: "Plk1 is negatively regulated by RNF8." in: Biochemical and biophysical research communications, Vol. 410, Issue 1, pp. 57-61, (2011) (PubMed).
: "Intermedilysin induces EGR-1 expression through calcineurin/NFAT pathway in human cholangiocellular carcinoma cells." in: Biochemical and biophysical research communications, Vol. 404, Issue 1, pp. 57-61, (2011) (PubMed).
: "
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Suppression of Polo like kinase 1 (PLK1) by p21(Waf1) mediates the p53-dependent prevention of caspase-independent mitotic death." in: Cellular signalling, Vol. 23, Issue 11, pp. 1816-23, (2011) (PubMed).
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- PLK1 (Polo-Like Kinase 1 (PLK1))
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Andere Bezeichnung
- PLK1
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Hintergrund
- Polo-like kinase 1 (Plk1) plays key roles in many aspects of mitosis. Suppression of Plk1 by p21(Waf1) is responsible for p53-dependent protection against adriamycin-induced caspase-independent mitotic death.
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Molekulargewicht
- 68 kDa
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Gen-ID
- 5347
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UniProt
- P53350
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Pathways
- Zellzyklus, M Phase
Target
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