TGFB1 Antikörper
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- Target Alle TGFB1 Antikörper anzeigen
- TGFB1 (Transforming Growth Factor, beta 1 (TGFB1))
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Reaktivität
- Human, Maus, Ratte, Rind (Kuh), Schaf, Kaninchen, Nerz
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser TGFB1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Spezifität
- Reacts with the dimeric (25 kDa) and monomeric (12.5 kDa) forms of TGF-beta under both non-reducing and reducing conditions respectively. This antibody recognizes both human platelet-derived and recombinant TGF-beta in ELISA
- Aufreinigung
- Protein G purified
- Immunogen
- TGF-beta from human platelets
- Klon
- TB21
- Isotyp
- IgG1
- Top Product
- Discover our top product TGFB1 Primärantikörper
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- Applikationshinweise
- Neutralizing: This antibody neutralizes TGF-beta activity in vitro, in an inhibition assay of CCL/64 cell growth and neutralizes the growth promoting action of TGF-beta in the NRK-49F colony forming assay. The effect of microinjection of this antibody into one blastomere of two cell stage Xenopus embryos indicated that it was able to neutralize effectively the bioactivity of TGF-beta in vivo. IHC: This antibody has been used to demonstrate TGF-beta in ovine ovarian tissue and human breast carcinoma at a dilution of 1:1000. As a consequence of the intense staining of the erythrocytes it is possible to locate a single cell within the ovarian stroma making it useful in locating very fine capillary networks within tissue. Western Blotting: This antibody when used at an antibody concentration of 5--20 ng/mL will allow visualization of 100 ng/lane of TGF-beta.
- Kommentare
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Myeloma, fusion partners: Sp2/0 Ag.14
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Whole IgG in 0.01M PBS, pH 7.0
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Thrombospondin-1 is a major activator of TGF-beta1 in vivo." in: Cell, Vol. 93, Issue 7, pp. 1159-70, (1998) (PubMed).
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Thrombospondin-1 is a major activator of TGF-beta1 in vivo." in: Cell, Vol. 93, Issue 7, pp. 1159-70, (1998) (PubMed).
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- Target
- TGFB1 (Transforming Growth Factor, beta 1 (TGFB1))
- Andere Bezeichnung
- TGF beta1 (TGFB1 Produkte)
- Synonyme
- CED antikoerper, DPD1 antikoerper, LAP antikoerper, TGFB antikoerper, TGFbeta antikoerper, TGF-beta antikoerper, TGF-BETA-1 antikoerper, TGF-beta5 antikoerper, ced antikoerper, dpd1 antikoerper, lap antikoerper, tgf-beta antikoerper, tgfb antikoerper, tgfb5 antikoerper, tgfbeta antikoerper, TGF-beta1 antikoerper, TGFbeta1 antikoerper, Tgfb antikoerper, Tgfb-1 antikoerper, ai39657 antikoerper, tgfb1 antikoerper, wu:fb13a07 antikoerper, xx:ai39657 antikoerper, TGFB1 antikoerper, csd antikoerper, cdb1 antikoerper, cdg2 antikoerper, csd1 antikoerper, csd2 antikoerper, csd3 antikoerper, ebmd antikoerper, lcd1 antikoerper, bigh3 antikoerper, cdgg1 antikoerper, betaig-h3 antikoerper, TGFB4 antikoerper, transforming growth factor beta 1 antikoerper, transforming growth factor beta-1 antikoerper, transforming growth factor beta 1 L homeolog antikoerper, transforming growth factor, beta 1 antikoerper, transforming growth factor, beta 1a antikoerper, transforming growth factor beta induced L homeolog antikoerper, TGFB1 antikoerper, Tgfb1 antikoerper, tgfb1.L antikoerper, tgfb1a antikoerper, tgfbi.L antikoerper
- Hintergrund
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Synonyms:
Camurati Engelmann disease antibody,CED antibody,Diaphyseal dysplasia 1 progressive antibody,DPD1antibody,LAP antibody,Latency-associated peptide antibody,TGF beta 1 antibody,TGF beta antibody,TGF-beta-1antibody,TGF-beta-5 antibody,TGF-beta1 antibody,TGFB 1 antibody,TGFB antibody,Tgfb-1 antibody,TGFB1antibody,TGFB1_HUMAN antibody,TGFbeta antibody,TGFbeta1 antibody,Transforming Growth Factor beta 1antibody,Transforming growth factor, beta 1a antibody - UniProt
- P01137
- Pathways
- EGFR Signaling Pathway, Dopaminergic Neurogenesis, Cellular Response to Molecule of Bacterial Origin, Glycosaminoglycan Metabolic Process, Regulation of Leukocyte Mediated Immunity, Regulation of Muscle Cell Differentiation, Positive Regulation of Immune Effector Process, Cell-Cell Junction Organization, Production of Molecular Mediator of Immune Response, Ribonucleoside Biosynthetic Process, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus, Autophagie, Cancer Immune Checkpoints
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