anti-CLEC7A (CLEC7A) Antikörper

Bezeichnung:: anti-C-Type Lectin Domain Family 7, Member A Antikörper (CLEC7A)

Auf www.antikoerper-online.de finden Sie aktuell 214 C-Type Lectin Domain Family 7, Member A (CLEC7A) Antikörper von 25 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen CLEC7A Kits (32) und CLEC7A Proteine (15) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 273 CLEC7A Produkte verfügbar.

Synonyme:: beta-GR, BGR, CANDF4, CLEC7A, Clec7b, CLECSF12, DECTIN1, RGD1565140

Alle Antikörper anzeigen	Gen	GeneID	UniProt
	CLEC7A	56644	Q6QLQ4
	CLEC7A	64581	Q9BXN2
	CLEC7A	502902
Alle Spezies anzeigen Weitere Synonyme anzeigen

Meistgesuchte Reaktivitäten zu anti-CLEC7A (CLEC7A) Antikörper

Wählen Sie die Spezies und Applikation aus

anti-Mouse (Murine) CLEC7A Antikörper:

anti-Human CLEC7A Antikörper:

anti-Rat (Rattus) CLEC7A Antikörper:

Alle verfügbaren anti-CLEC7A Antikörper

Sie gelangen zu unserer vorgefilterten Suche.

Verknüpfte Pathways mit anti-CLEC7A Antikörper

Activation of Innate immune Response

Weitere Produktkategorien zu CLEC7A Antikörper

Am meisten referenzierte anti-CLEC7A Antikörper

Human Monoclonal CLEC7A Primary Antibody für BR, CyTOF - ABIN5012887 : Cabezón, Sintes, Llinàs, Benitez-Ribas: Analysis of HLDA9 mAbs on plasmacytoid dendritic cells. in Immunology letters 2010 (PubMed)
Show all 19 Pubmed References
Human Monoclonal CLEC7A Primary Antibody für FACS - ABIN4897737 : Cunha, Di Ianni, Bozza, Giovannini, Zagarella, Zelante, DAngelo, Pierini, Pitzurra, Falzetti, Carotti, Perruccio, Latgé, Rodrigues, Velardi, Aversa, Romani, Carvalho et al.: Dectin-1 Y238X polymorphism associates with susceptibility to invasive aspergillosis in hematopoietic transplantation through impairment of both recipient- and donor-dependent mechanisms of ... in Blood 2010 (PubMed)
Show all 6 Pubmed References
Mouse (Murine) Monoclonal CLEC7A Primary Antibody für FACS - ABIN2473272 : Anderson, Wilkinson, Abou-Saleh, Farrar, Blair: Enhancement of recovery from psychiatric illness by methylfolate. in The British journal of psychiatry : the journal of mental science 1992 (PubMed)
Show all 4 Pubmed References
Mouse (Murine) Monoclonal CLEC7A Primary Antibody für FACS - ABIN2473273 : Brown, Taylor, Reid, Willment, Williams, Martinez-Pomares, Wong, Gordon: Dectin-1 is a major beta-glucan receptor on macrophages. in The Journal of experimental medicine 2002 (PubMed)
Show all 4 Pubmed References
Mouse (Murine) Monoclonal CLEC7A Primary Antibody für IHC (fro), FACS - ABIN2473265 : Taylor, Brown, Reid, Willment, Martinez-Pomares, Gordon, Wong: The beta-glucan receptor, dectin-1, is predominantly expressed on the surface of cells of the monocyte/macrophage and neutrophil lineages. in Journal of immunology (Baltimore, Md. : 1950) 2002 (PubMed)
Show all 4 Pubmed References
Mouse (Murine) Monoclonal CLEC7A Primary Antibody für FACS - ABIN2473267 : Goodridge, Shimada, Wolf, Hsu, Becker, Lin, Underhill: Differential use of CARD9 by dectin-1 in macrophages and dendritic cells. in Journal of immunology (Baltimore, Md. : 1950) 2009 (PubMed)
Show all 4 Pubmed References

Weitere Antikörper gegen CLEC7A Interaktionspartner

Pig (Porcine) C-Type Lectin Domain Family 7, Member A (CLEC7A) Interaktionspartner

These results suggest that functionally neutral polymorphisms in dectin-1 are widespread in pig populations
recognition of beta-glucans appeared cell type-specific as both dectin-1 and CR3 (zeige ITGAM Antikörper) are involved in the beta-glucan-mediated responses in pig macrophages.

Mouse (Murine) C-Type Lectin Domain Family 7, Member A (CLEC7A) Interaktionspartner

Dectin-1 plays an important role in host defense against systemic Candida glabrata infections.
These results identify dectin-1-activated dendritic cells as a powerful inducer of Th9 cells and antitumour immunity and may have important clinical implications.
These findings demonstrate that Dectin-1, Irak1 (zeige IRAK1 Antikörper), and Rip2 (zeige ARHGDIG Antikörper) are involved in response to Aspergillus fumigatus infection. Dectin-1 modulates the expression of Irak1 (zeige IRAK1 Antikörper) and Rip2 (zeige ARHGDIG Antikörper).
Feeding Guar gum fiber increases SOCS-1 (zeige SOCS1 Antikörper), TLR2 and dectin-1 expression in dextran sodium sulfate administered and normal mice.
Dectin-1 agonists selectively induce IgG1 class switching by direct stimulation of Dectin-1 on LPS (zeige TLR4 Antikörper)-activated B cells resulting in selective production of IgG1.
These results suggest that the intracellular domain, not ligand-binding domain, of Dectin-1 determines the species-specific ligand profile.
this study shows the critical role of Dectin-1 for inflammasome activation, restriction of parasite replication in macrophages, and mouse resistance to Leishmania amazonensis infection in vivo
results demonstrate that Dectin-1-triggered Card9 (zeige CARD9 Antikörper) signaling but not inflammasome activation can potently cross-prime Ag-specific cytotoxic T-cells, suggesting that this pathway would be a candidate for immunotherapy and vaccine development
Dectin 1 is highly expressed on macrophages in pancreatic ductal adenocarcinoma (PDA). Clec7a deletion is protective against PDA, however Clec7a does not have direct protumorigenic effects on transformed pancreatic ductal epithelial cells.
Dectin-1 does not play a major role in in phagocytosis and innate defense by phagocytes against Cryptococcus neoformans spores.

Human C-Type Lectin Domain Family 7, Member A (CLEC7A) Interaktionspartner

Dectin-1 receptor blockage decreased the IL-12 (zeige IL12A Antikörper), IL-17 (zeige IL17A Antikörper), IL-10 (zeige IL10 Antikörper) and TNF-alpha (zeige TNF Antikörper) levels indicating the participation of such receptor in the induction of these cytokines.
Dectin-1 is expressed on mDCs and is down-regulated after contact with A. fumigatus, indicating that mDCs recognize A. fumigatus via this receptor. Blocking of Dectin-1, followed by stimulation with depleted zymosan diminished the up-regulation of the T-cell co-stimulatory molecules CD40 (zeige CD40 Antikörper), CD80 (zeige CD80 Antikörper), HLA-DR and CCR7 (zeige CCR7 Antikörper) on mDCs and led to decreased release of the cytokines TNF-alpha (zeige TNF Antikörper), IL-8 (zeige IL8 Antikörper), IL-1beta (zeige IL1B Antikörper) and IL-10 (zeige IL10 Antikörper).
this study shows that Dectin-1 is essential for IL-1beta (zeige IL1B Antikörper) production through JNK (zeige MAPK8 Antikörper) activation and apoptosis in Aspergillus fumigatus keratitis
high tumoral dectin-1 expression was an independent predictor of adverse clinical outcome in ccRCC patients. This molecule and established nomograms might help clinicians in future decision making and therapeutic developments
Dectin-1 may have therapeutic implications as a biomarker for metabolic dysregulation in humans.
theses data suggest miR (zeige MLXIP Antikörper)-146a may play the potent negative feedback regulator in inflammatory response following Dectin-1 stimulation
These results suggest that the intracellular domain, not ligand-binding domain, of Dectin-1 determines the species-specific ligand profile.
Unique cytokine secretion and varying expression levels of n Dectin-1 isoforms on monocyte-derived cells may indicate distinct isoform usage as a cell type-specific mechanism of regulating anti-fungal immunity.
Dectin 1 is highly expressed on macrophages in pancreatic ductal adenocarcinoma.
Dectin-1-mediated activation of the Syk (zeige SYK Antikörper), MAPKs, PI3K (zeige PIK3CA Antikörper) and NF-kappaB (zeige NFKB1 Antikörper) signaling pathways contributes to F. proliferatum-stimulated CXCL-8 (zeige IL8 Antikörper) release from BEAS-2B cells and provides an important basis for developing novel therapeutic strategies in clinical allergy.

Cow (Bovine) C-Type Lectin Domain Family 7, Member A (CLEC7A) Interaktionspartner

CLEC7a genetic variant c.589A>G was significantly associated (p = 0.008) with Mycobacterium avium ssp. paratuberculosis infection in Holsteins cattle.

CLEC7A Antigen-Profil

Beschreibung des Gens

This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. The encoded glycoprotein is a small type II membrane receptor with an extracellular C-type lectin-like domain fold and a cytoplasmic domain with an immunoreceptor tyrosine-based activation motif. It functions as a pattern-recognition receptor that recognizes a variety of beta-1,3-linked and beta-1,6-linked glucans from fungi and plants, and in this way plays a role in innate immune response. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region.

Alternative names and synonyms associated with CLEC7A

C-type lectin domain containing 7A (CLEC7A) Antikörper
C-type lectin domain family 7, member a (Clec7a) Antikörper
C-type lectin domain containing 7A (Clec7a) Antikörper

beta-GR Antikörper
BGR Antikörper
CANDF4 Antikörper
CLEC7A Antikörper
Clec7b Antikörper
CLECSF12 Antikörper
DECTIN1 Antikörper
RGD1565140 Antikörper

Bezeichner auf Proteinebene für CLEC7A

dendritic cell-associated C-type lectin 1 , C-type lectin domain family 7, member A , C-type lectin domain family 7 member A , dectin 1 , C-type (calcium dependent, carbohydrate recognition domain) lectin, superfamily member 12 , C-type lectin superfamily member 12 , DC-associated C-type lectin 1 , beta-glucan receptor , dectin-1 , C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 12 , dendritic cell-associated C-type lectin-1 , lectin-like receptor 1

GENE ID	SPEZIES
473361	Pan troglodytes
611385	Canis lupus familiaris
678685	Ovis aries
100038025	Sus scrofa
56644	Mus musculus
64581	Homo sapiens
532865	Bos taurus
502902	Rattus norvegicus
574356	Macaca mulatta
100339146	Oryctolagus cuniculus

Ausgewählte Anbieter für anti-CLEC7A (CLEC7A) Antikörper

Haben Sie etwas anderes gesucht?

Telefon:	+1 877 302 8632
Fax:	+1 888 205 9894 (Toll-free)
E-Mail:	orders@antikoerper-online.de

Show all anti-C-Type Lectin Domain Family 7, Member A (CLEC7A) Antikörper with Pubmed References