anti-phosphofurin Acidic Cluster Sorting Protein 2 (PACS2) Antikörper

Multifunctional sorting protein that controls the endoplasmic reticulum (ER)-mitochondria communication, including the apposition of mitochondria with the ER and ER homeostasis. Zusätzlich bieten wir Ihnen PACS2 Proteine (4) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
PACS2 23241 Q86VP3
PACS2 217893  
PACS2    
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Top anti-PACS2 Antikörper auf antikoerper-online.de

Showing 10 out of 25 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB WB Suggested Anti-PACS2 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:312500 Positive Control: A549 cell lysate 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Kaninchen Unkonjugiert IHC (p), WB PACS2 Antibody (C-term) (ABIN657066) immunohistochemistry analysis in formalin fixed and paraffin embedded human skeletal muscle followed by peroxidase conjugation of the secondary antibody and DAB staining. 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Human Kaninchen Unkonjugiert IHC, IHC (p) Immunohistochemistry: PACS2 Antibody [NBP1-81496] - Staining of human liver shows strong cytoplasmic positivity in hepatocytes. 0.1 mL Anmelden zum Anzeigen 10 bis 13 Tage
$439.69
Details
Human Kaninchen Unkonjugiert ICC, IF Immunocytochemistry/Immunofluorescence: PACS2 Antibody  - Staining of human cell line U-2 OS shows localization to mitochondria. 100 μL Anmelden zum Anzeigen 10 bis 13 Tage
$439.69
Details
Human Kaninchen Biotin IHC, ELISA, WB   200 μL Anmelden zum Anzeigen 7 bis 9 Tage
$1,013.83
Details
Human Kaninchen Alkaline Phosphatase (AP) IHC, ELISA, WB   200 μL Anmelden zum Anzeigen 7 bis 9 Tage
$1,013.83
Details
Human Kaninchen APC IHC, ELISA, WB   200 μL Anmelden zum Anzeigen 7 bis 9 Tage
$1,013.83
Details
Human Kaninchen FITC IHC, ELISA, WB   200 μL Anmelden zum Anzeigen 7 bis 9 Tage
$1,013.83
Details
Human Kaninchen PE IHC, ELISA, WB   200 μL Anmelden zum Anzeigen 7 bis 9 Tage
$1,013.83
Details
Human Kaninchen HRP IHC, ELISA, WB   200 μL Anmelden zum Anzeigen 7 bis 9 Tage
$1,013.83
Details

PACS2 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
Human , ,


, , , , ,
Mouse (Murine)


Rat (Rattus)


Am meisten referenzierte anti-PACS2 Antikörper

  1. Human Polyclonal PACS2 Primary Antibody für IHC, IHC (p) - ABIN4343360 : Aslan, You, Williamson, Endig, Youker, Thomas, Shu, Du, Milewski, Brush, Possemato, Sprott, Fu, Greis, Runckel, Vogel, Thomas: Akt and 14-3-3 control a PACS-2 homeostatic switch that integrates membrane traffic with TRAIL-induced apoptosis. in Molecular cell 2009 (PubMed)

Weitere Antikörper gegen PACS2 Interaktionspartner

Human phosphofurin Acidic Cluster Sorting Protein 2 (PACS2) Interaktionspartner

  1. Missense Mutation in PACS2 gene is associated with Neurodevelopmental Disorders.

  2. cIAPs constitutively downregulate PACS-2 by polyubiquitination and proteasomal degradation, thereby restraining TRAIL-induced killing of liver cancer cells

  3. Tumor necrosis factor (zeige TNF Antikörper)-related apoptosis-inducing ligand (TRAIL) protein-induced lysosomal translocation of proapoptotic effectors is mediated by phosphofurin acidic cluster sorting protein-2.

  4. subcellular localization and function of polycystin-2 (zeige PKD2 Antikörper) are directed by phosphofurin acidic cluster sorting protein (PACS)-1 (zeige PACS1 Antikörper) and PACS-2

  5. PACS-2 as a novel sorting protein that links the endoplasmic reticulum (ER)-mitochondria axis to ER homeostasis

  6. PACS-2 is required for Nef action and sorting of itinerant membrane cargo in the TGN (zeige TG Antikörper)/endosomal system

  7. the phosphorylation state of the calnexin (zeige CANX Antikörper) cytosolic domain and its interaction with PACS-2 sort the chaperone between domains of the ER and the plasma membrane

  8. Results identify PACS-2 as an essential TRAIL effector, and show that Akt (zeige AKT1 Antikörper) cooperates with 14-3-3 (zeige YWHAQ Antikörper) to regulate the homeostatic and apoptotic properties of PACS-2 that mediate TRAIL action.

Mouse (Murine) phosphofurin Acidic Cluster Sorting Protein 2 (PACS2) Interaktionspartner

  1. CS-2 (zeige MYOZ1 Antikörper) traffics to the nucleus where it regulates SIRT1 (zeige SIRT1 Antikörper)-mediated p53 (zeige TP53 Antikörper) deacetylation. PACS-2 binds SIRT1 (zeige SIRT1 Antikörper) in vitro and directly inhibits SIRT1 (zeige SIRT1 Antikörper)-catalyzed p53 (zeige TP53 Antikörper) deacetylation.

  2. PACS-2 is required for Nef action and sorting of itinerant membrane cargo in the TGN (zeige TG Antikörper)/endosomal system

  3. Results identify PACS-2 as an essential TRAIL effector, and show that Akt (zeige AKT1 Antikörper) cooperates with 14-3-3 (zeige YWHAQ Antikörper) to regulate the homeostatic and apoptotic properties of PACS-2 that mediate TRAIL action.

PACS2 Antigen-Profil

Protein Überblick

Multifunctional sorting protein that controls the endoplasmic reticulum (ER)-mitochondria communication, including the apposition of mitochondria with the ER and ER homeostasis. In addition, in response to apoptic inducer, translocates BIB to mitochondria, which initiates a sequence of events including the formation of mitochondrial truncated BID, the release of cytochrome c, the activation of caspase-3 thereby causing cell death. May also be involved in ion channel trafficking, directing acidic cluster-containing ion channels to distinct subcellular compartments.

Genbezeichner und Symbole assoziert mit PACS2

  • phosphofurin acidic cluster sorting protein 2 (PACS2) Antikörper
  • phosphofurin acidic cluster sorting protein 2 (Pacs2) Antikörper
  • 6720425G15Rik Antikörper
  • AW208651 Antikörper
  • AW489976 Antikörper
  • E230011J22 Antikörper
  • mKIAA0602 Antikörper
  • PACS-2 Antikörper
  • Pacs1l Antikörper

Bezeichner auf Proteinebene für PACS2

PACS1-like protein , PACS-2

GENE ID SPEZIES
23241 Homo sapiens
217893 Mus musculus
Ausgewählte Anbieter für anti-PACS2 (PACS2) Antikörper
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