V-Set Domain Containing T Cell Activation Inhibitor 1 Proteine (VTCN1)

VTCN1 encodes a protein belonging to the B7 costimulatory protein family. Zusätzlich bieten wir Ihnen VTCN1 Antikörper (208) und VTCN1 Kits (28) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
VTCN1 242122 Q7TSP5
VTCN1 79679 Q7Z7D3
VTCN1 295322 Q501W4
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Top VTCN1 Proteine auf antikoerper-online.de

Showing 10 out of 37 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
HEK-293 Cells Human His tag 50 μg Anmelden zum Anzeigen 2 bis 3 Tage
$595.00
Details
Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 30 bis 35 Tage
$4,744.22
Details
Insektenzellen Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Anmelden zum Anzeigen 50 bis 55 Tage
$6,616.87
Details
HEK-293 Cells Human His tag Human B7-H4, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%. Immobilized Human B7-H4, His Tag  with a linear range of 0.4-6 ng/mL. 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$275.00
Details
HEK-293 Cells Human AVI tag,Biotin,His tag Biotinylated Human B7-H4 (recommended for biopanning) on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%. Measured by its binding ability in a functional ELISA. Immobilized Anti-B7-H4 mAb,Human IgG1 at 2μg/mL (100 μL/well) can bind Biotinylated Human B7-H4, His Tag  with a linear range of 3-48 ng/mL. 200 μg Anmelden zum Anzeigen 5 Days
$1,518.00
Details
Escherichia coli (E. coli) Human His tag,GST tag 100 μg Anmelden zum Anzeigen 15 bis 18 Tage
$768.00
Details
Human Cells Human Fc Tag 100 μg Anmelden zum Anzeigen 20 bis 21 Tage
$382.80
Details
Human Cells Maus Fc Tag 100 μg Anmelden zum Anzeigen 20 bis 21 Tage
$382.80
Details
Escherichia coli (E. coli) Human GST tag V-Set Domain Containing T Cell Activation Inhibitor 1 (VTCN1) (AA 26-258), (partial) protein (GST tag) 50 μg Anmelden zum Anzeigen 13 bis 16 Tage
$242.00
Details
HEK-293 Cells Maus His tag   100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$550.00
Details

VTCN1 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Mouse (Murine) , , ,
,
Human , , ,
, , , , , , ,
Rat (Rattus) , ,

Weitere Proteine zu V-Set Domain Containing T Cell Activation Inhibitor 1 (VTCN1) Interaktionspartnern

Mouse (Murine) V-Set Domain Containing T Cell Activation Inhibitor 1 (VTCN1) Interaktionspartner

  1. this study shows that B7-H4 knockout hosts mount greater tumor-associated anti-tumor T cell responses and display reduced tumors

  2. Results highlight an importance of VTCN1 stabilization on cell surfaces for the restoration of altered balance of immune control during T1D.

  3. Ablation of B7-H3 (zeige CD276 Proteine) but Not B7-H4 Results in Highly Increased Tumor Burden in a Murine Model of Spontaneous Prostate Cancer

  4. B7-H4 expression by nonhematopoietic cells in the tumor microenvironment promotes antitumor immunity.

  5. that B7x can modulate kidney damage in autoimmune diseases including lupus nephritis and anti-glomerular basement membrane disease

  6. B7-H4 can inhibit both antitumor T cells and protumor myeloid-derived suppressor cells (

  7. The endogenous expression of B7-H4 in donor beta cells from transgenic mice prolongs islet allograft survival, confirming the negative role of B7-H4 in regulating alloreactive T-cell responses.

  8. Local overexpression of B7x on pancreatic beta cells is sufficient to abolish CD8 (zeige CD8A Proteine) T cell-induced diabetes.

  9. B7-H4 expression may influence the outcome of T-cell tumor cell interactions. Tumor-associated macrophage induced membrane-bound B7-H4 on lung cancer cell represents a novel mechanism by which lung cancer cells evade immune recognition and destruction.

  10. Overexpression of B7-H4 was shown in tumor infiltrated dendritic cells.

Human V-Set Domain Containing T Cell Activation Inhibitor 1 (VTCN1) Interaktionspartner

  1. The decrease of B7-H4 expression in salivary glands of Sjogren's syndrome patients contributes to the defect of negatively regulating the inflammation caused by CD4 (zeige CD4 Proteine)(+) T cells.

  2. Preclinical investigation into B7-H4-specific chimeric antigen receptor (CAR) T cells, antibody-mediated blockade of B7-H4, and anti-B7-H4 drug conjugates has shown antitumor efficacy in mouse models.

  3. This meta-analysis demonstrated that high B7-H4 expression is an unfavorable prognostic factor in NSCLC.

  4. This meta-analysis clarified that high B7-H4 expression in tissue was significantly associated with poor survival in patients with solid tumors.

  5. in pulmonary adenocarcinoma presenting with SPN (zeige SPN Proteine), nuclear membrane localization of B7-H4 within the tumor cells is associated with increased malignancy

  6. Study reportes that B7-H3 (zeige CD276 Proteine) and B7-H4 are highly expressed in human esophageal cancer tissues and significantly associated with tumor invasion.

  7. Results revealed B7-H4 to be associated with poor prognosis in patients with pancreatic cancer liver metastasis. B7-H4 may promote pancreatic cancer metastasis.

  8. PD-L1 (zeige CD274 Proteine), IDO-1 (zeige IDO1 Proteine), and B7-H4 are differentially expressed in human lung carcinomas and show limited co-expression. While PD-L1 (zeige CD274 Proteine) and IDO-1 (zeige IDO1 Proteine) are associated with increased tumor-infiltrating lymphoycte and IFN-gamma (zeige IFNG Proteine) stimulation, B7-H4 is not.

  9. B7-H4 activation on Mphis/microglia in the microenvironment of gliomas is an important immunosuppressive event blocking effective T-cell immune responses.

  10. Knockdown of B7-H4 significantly up-regulated 57 miRNAs and down-regulated 14 miRNAs.

VTCN1 Protein Überblick

Protein Überblick

This gene encodes a protein belonging to the B7 costimulatory protein family. Proteins in this family are present on the surface of antigen-presenting cells and interact with ligand bound to receptors on the surface of T cells. Studies have shown that high levels of the encoded protein has been correlated with tumor progression. A pseudogene of this gene is located on chromosome 20. Multiple transcript variants encoding different isoforms have been found for this gene.

Genbezeichner und Symbole assoziert mit VTCN1

  • V set domain containing T cell activation inhibitor 1 L homeolog (vtcn1.L)
  • V-set domain containing T cell activation inhibitor 1 (VTCN1)
  • V-set domain containing T-cell activation inhibitor 1 (VTCN1)
  • V set domain containing T cell activation inhibitor 1 (vtcn1)
  • V-set domain containing T cell activation inhibitor 1 (Vtcn1)
  • B7-H4 Protein
  • B7h.5 Protein
  • B7H4 Protein
  • B7S1 Protein
  • B7X Protein
  • BC032925 Protein
  • PRO1291 Protein
  • RGD1311204 Protein
  • VCTN1 Protein

Bezeichner auf Proteinebene für VTCN1

V-set domain-containing T-cell activation inhibitor 1 , V-set domain containing T cell activation inhibitor 1 , V-set domain containing T-cell activation inhibitor 1 , immune costimulatory protein B7-H4 , t cell costimulatory molecule B7x , B7 family member, H4 , B7 superfamily member 1 , T cell costimulatory molecule B7x , T-cell costimulatory molecule B7x

GENE ID SPEZIES
379070 Xenopus laevis
418323 Gallus gallus
469433 Pan troglodytes
493551 Xenopus (Silurana) tropicalis
242122 Mus musculus
79679 Homo sapiens
295322 Rattus norvegicus
Ausgewählte Anbieter für VTCN1 Proteine (VTCN1)
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