V-Set Domain Containing T Cell Activation Inhibitor 1 (VTCN1) (AA 29-258) (Active) protein (His tag) Protein
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- Target Alle VTCN1 Proteine anzeigen
- VTCN1
- Protein-Typ
- Recombinant
- Biologische Aktivität
- Active
- Proteineigenschaft
- AA 29-258
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Spezies
- Human
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Quelle
- HEK-293 Cells
- Aufreinigungstag / Konjugat
- Dieses VTCN1 Protein ist gelabelt mit His tag.
- Sequenz
- AA 29-258
- Produktmerkmale
- This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 26.1 kDa. The protein migrates as 43-60 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
- Reinheit
- >95 % as determined by SDS-PAGE.
- Sterilität
- 0.22 μm filtered
- Endotoxin-Niveau
- Less than 1.0 EU per μg by the LAL method.
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V-Set Domain Containing T Cell Activation Inhibitor 1 (VTCN1) (AA 33-194) protein (Fc Tag) Protein
VTCN1 Spezies: Human Wirt: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
V-Set Domain Containing T Cell Activation Inhibitor 1 (VTCN1) (AA 29-258) (Active) protein (His tag,Biotin) ProteinVTCN1 Spezies: Human Wirt: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
V-Set Domain Containing T Cell Activation Inhibitor 1 (VTCN1) (AA 29-258) (Active) protein (His tag,AVI tag,Biotin) ProteinVTCN1 Spezies: Human Wirt: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Func Active
V-Set Domain Containing T Cell Activation Inhibitor 1 (VTCN1) (AA 33-194) protein (His tag,AVI tag,Biotin) ProteinVTCN1 Spezies: Human Wirt: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Func
V-Set Domain Containing T Cell Activation Inhibitor 1 (VTCN1) (AA 25-282) protein (rho-1D4 tag) ProteinCrystallography grade VTCN1 Spezies: Human Wirt: Insektenzellen Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. Crys, ELISA, SDS, WB
V-Set Domain Containing T Cell Activation Inhibitor 1 (VTCN1) (AA 26-258), (partial) protein (GST tag) ProteinVTCN1 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant 90 % ELISA
V-Set Domain Containing T Cell Activation Inhibitor 1 (VTCN1) (AA 33-194) (Active) protein (Fc Tag) ProteinVTCN1 Spezies: Human Wirt: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
V-Set Domain Containing T Cell Activation Inhibitor 1 (VTCN1) (AA 33-194) protein (His tag) ProteinVTCN1 Spezies: Human Wirt: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE.
V-Set Domain Containing T Cell Activation Inhibitor 1 (VTCN1) (AA 33-192) protein (His tag) ProteinVTCN1 Spezies: Rhesusaffen Wirt: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
V-Set Domain Containing T Cell Activation Inhibitor 1 (VTCN1) (AA 33-191) protein (His tag) ProteinVTCN1 Spezies: Maus Wirt: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Buffer
- PBS, pH 7.4
- Handhabung
- Please avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C), After reconstitution under sterile conditions for 3 months (-70 °C).
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- Target
- VTCN1
- Andere Bezeichnung
- B7-H4 (VTCN1 Produkte)
- Synonyme
- B7h4, B7s1, B7x, BC032925, B7-H4, B7H4, B7S1, B7X, B7h.5, PRO1291, VCTN1, RGD1311204, V set domain containing T cell activation inhibitor 1 L homeolog, V-set domain containing T cell activation inhibitor 1, V-set domain containing T-cell activation inhibitor 1, V set domain containing T cell activation inhibitor 1, vtcn1.L, VTCN1, vtcn1, Vtcn1
- Hintergrund
- V-set domain-containing T-cell activation inhibitor 1 (VTCN1) is also known as Immune costimulatory protein B7-H4, Protein B7S1, T-cell costimulatory molecule B7x, B7H4, which belongs to the immunoglobulin superfamily and BTN/MOG family. VTCN1 contains two Ig-like V-type (immunoglobulin-like) domains. The expression of VTCN1 is up-regulated by IL6 and IL10 and is inhibited by GM-CSF and IL4 on antigen-presenting cells (APCs). VTCN1 / B7-H4 negatively regulates T-cell-mediated immune response by inhibiting T-cell activation, proliferation, cytokine production and development of cytotoxicity. VTCN1 involved in promoting epithelial cell transformation.
- Molekulargewicht
- 26.4 kDa
- NCBI Accession
- NP_078902
