anti-Ubiquitin-Like with PHD and Ring Finger Domains 2, E3 Ubiquitin Protein Ligase (UHRF2) Antikörper

UHRF2 encodes a nuclear protein which is involved in cell-cycle regulation. Zusätzlich bieten wir Ihnen Ubiquitin-Like with PHD and Ring Finger Domains 2, E3 Ubiquitin Protein Ligase Proteine (4) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
UHRF2 115426 Q96PU4
UHRF2 109113 Q7TMI3
UHRF2 309331  
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Top anti-Ubiquitin-Like with PHD and Ring Finger Domains 2, E3 Ubiquitin Protein Ligase Antikörper auf antikoerper-online.de

Showing 10 out of 76 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert IHC, WB WB Suggested Anti-UHRF2 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:62500  Positive Control:  Jurkat cell lysate Human Heart 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$319.00
Details
Rind (Kuh) Kaninchen Unkonjugiert WB WB Suggested Anti-UHRF2 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:62500  Positive Control:  Human Liver 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Kaninchen Unkonjugiert IHC (p), WB NIRF was detected in paraffin-embedded sections of mouse intestine tissues using rabbit anti- NIRF Antigen Affinity purified polyclonal antibody at 1 μg/mL. The immunohistochemical section was developed using SABC method NIRF was detected in paraffin-embedded sections of rat intestine tissues using rabbit anti- NIRF Antigen Affinity purified polyclonal antibody at 1 μg/mL. The immunohistochemical section was developed using SABC method 100 μg Anmelden zum Anzeigen 4 bis 6 Tage
$280.00
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Human Maus Unkonjugiert IF, WB Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (36.74 KDa) . Dilution: 1:500~1000 100 μg Anmelden zum Anzeigen 8 bis 11 Tage
$527.50
Details
Rind (Kuh) Kaninchen Unkonjugiert WB WB Suggested Anti-Uhrf2 Antibody  Positive Control: Lane 1: 60ug HCT116 lysate  Primary Antibody Dilution :  1:1000 Secondary Antibody : Anti rabbit-HRP  Secondry Antibody Dilution :  1:5,000 Submitted by: Chinweike Ukomadu, Brigham and Women's Hospital, Boston WB Suggested Anti-Uhrf2 Antibody Titration: 1.0 ug/ml Positive Control: Mouse Pancreas 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
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Human Kaninchen Unkonjugiert IF, IHC, WB 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$335.00
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Human Kaninchen Unkonjugiert IF, IHC, WB Immunohistochemistry of paraffin-embedded human liver cancer using UHRF2 antibody at dilution of 1:200 (400x lens). 100 μL Anmelden zum Anzeigen 16 Days
$366.77
Details
Rind (Kuh) Kaninchen Unkonjugiert IHC, IHC (p), WB 50 μg Anmelden zum Anzeigen 11 bis 14 Tage
$551.83
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Fledermaus Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 11 bis 14 Tage
$551.83
Details
Human Kaninchen Unkonjugiert ELISA, ICC, IF, IHC, WB Western blot analysis of Jurkat whole cell lysates, using UHRF2  Antibody. The lane on the left is treated with the antigen-specific peptide. ABIN6277189 at 1/100 staining Rat kidney tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22¡ãC. An HRP conjugated goat anti-rabbit antibody was used as the secondary 100 μL Anmelden zum Anzeigen 11 bis 12 Tage
$390.77
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Am meisten referenzierte anti-Ubiquitin-Like with PHD and Ring Finger Domains 2, E3 Ubiquitin Protein Ligase Antikörper

  1. Cow (Bovine) Polyclonal UHRF2 Primary Antibody für IHC, WB - ABIN2776012 : Liu, Zhu, Zhou, Zhang, Xu, Li: [Analysis of diagnosis and misdiagnosis of pulmonary thromboembolism in emergency]. in Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue 2004 (PubMed)
    Show all 2 Pubmed References

Weitere Antikörper gegen Ubiquitin-Like with PHD and Ring Finger Domains 2, E3 Ubiquitin Protein Ligase Interaktionspartner

Human Ubiquitin-Like with PHD and Ring Finger Domains 2, E3 Ubiquitin Protein Ligase (UHRF2) Interaktionspartner

  1. UHRF2 may be a negative regulator of EMT and a novel prognostic biomarker for ESCC.

  2. UHRF2 expression is reduced in some leukemia cell lines, this correlates with promoter hypermethylation, and similar UHRF2 methylation profiles are seen in primary human leukemia samples. Thus, UHRF2 and 5hmC are widely present in differentiated human tissues, and UHRF2 protein is poorly expressed or mislocalized in diverse human cancers.

  3. Here, we report the complex structure of PCNA and the peptide ((784)NEILQTLLDLFFPGYSK(800)) derived from UHRF2 that contains a PIP box. Structural analysis combined with mutagenesis experiments provide the molecular basis for the recognition of UHRF2 by PCNA via PIP-box.

  4. Results show that UHRF2 down-regulates a number of epithelial-mesenchymal transition markers and up-regulates the expression of transcription factors. The study also suggests that UHRF2 play a role in tumor metastasis.

  5. TIP60 acted downstream of UHRF2 to regulate H3K9ac and H3K14ac expression.

  6. The overexpression of UHRF2 increased the expression of H3K9ac in L02 normal cells (P<0.01), but decreased the expression of histone H3 lysine 9 acetylation in HepG2 cancer cells.

  7. study suggests that ZNF618 is a key protein that regulates UHRF2 function as a specific 5hmC reader in vivo.

  8. UHRF2 may contribute to the progression of colon carcinogenesis and function as a novel prognostic indicator after curative operation

  9. A hydrogen bond between the hydroxyl group of 5hmC and UHRF2-SRA is critical for their preferential binding.

  10. UHRF2 is a transcriptional target of E2F, that it directly interacts with E2F1.

  11. UHRF2, the homolog of UHRF1, interacts with N-methylpurine DNA glycosylase (MPG) in cancer cells.

  12. Low UHRF2 mRNA expression is associated with malignant glioma.

  13. UHRF2, a ubiquitin E3 ligase, acts as a small ubiquitin-like modifier E3 ligase for zinc finger protein 131

  14. NIRF may contribute to the coupling between the cell cycle network and the epigenetic landscape

  15. In the present study, ubiquitin ligase, NIRF, binds to hepatitis B virus core protein and leads to the proteasome-mediated degradation of hepatitis B virus core protein in vivo.

  16. NIRF is immediately adjacent to the single nucleotide polymorphism rs719725, which is reportedly associated with the risk of colorectal cancer.

  17. NIRF is frequently upregulated in colorectal cancer and its oncogenicity can be suppressed by let-7a microRNA.

  18. the cooperative interplay of Uhrf2 domains may contribute to a tighter epigenetic control of gene expression in differentiated cells

  19. NIRF is involved in cell-cycle regulation

  20. NIRF has ubiquitination activity, the hallmark of a ubiquitin ligase. PCNP was readily ubiquitinated in 293 and COS-7 cells, and NIRF ubiquitinated PCNP in vitro as well as in vivo.

Ubiquitin-Like with PHD and Ring Finger Domains 2, E3 Ubiquitin Protein Ligase (UHRF2) Antigen-Profil

Protein Überblick

This gene encodes a nuclear protein which is involved in cell-cycle regulation. The encoded protein is a ubiquitin-ligase capable of ubiquinating PCNP (PEST-containing nuclear protein), and together they may play a role in tumorigenesis. The encoded protein contains an NIRF_N domain, a PHD finger, a set- and ring-associated (SRA) domain, and a RING finger domain and several of these domains have been shown to be essential for the regulation of cell proliferation. This protein may also have a role in intranuclear degradation of polyglutamine aggregates. Alternative splicing results in multiple transcript variants some of which are non-protein coding.

Genbezeichner und Symbole assoziert mit UHRF2

  • ubiquitin like with PHD and ring finger domains 2 (UHRF2) Antikörper
  • ubiquitin-like, containing PHD and RING finger domains 2 (Uhrf2) Antikörper
  • ubiquitin like with PHD and ring finger domains 2 (Uhrf2) Antikörper
  • 2310065A22Rik Antikörper
  • AI426270 Antikörper
  • AW214556 Antikörper
  • D130071B19Rik Antikörper
  • Nirf Antikörper
  • RNF107 Antikörper
  • URF2 Antikörper

Bezeichner auf Proteinebene für UHRF2

E3 ubiquitin-protein ligase UHRF2 , Np95-like ring finger protein , RING finger protein 107 , np95/ICBP90-like RING finger protein , nuclear protein 97 , nuclear zinc finger protein NP97 , ubiquitin-like PHD and RING finger domain-containing protein 2 , ubiquitin-like, containing PHD and RING finger domains, 2 , ubiquitin-like-containing PHD and RING finger domains protein 2 , nuclear zinc finger protein Np97 , ubiquitin-like, containing PHD and RING finger domains 2

GENE ID SPEZIES
115426 Homo sapiens
474702 Canis lupus familiaris
613759 Bos taurus
109113 Mus musculus
309331 Rattus norvegicus
100715709 Cavia porcellus
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