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anti-Ubiquitin-Like with PHD and Ring Finger Domains 2, E3 Ubiquitin Protein Ligase (UHRF2) Antikörper

UHRF2 encodes a nuclear protein which is involved in cell-cycle regulation. Zusätzlich bieten wir Ihnen Ubiquitin-Like with PHD and Ring Finger Domains 2, E3 Ubiquitin Protein Ligase Proteine (4) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
UHRF2 115426 Q96PU4
UHRF2 109113 Q7TMI3
UHRF2 309331  
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Top anti-Ubiquitin-Like with PHD and Ring Finger Domains 2, E3 Ubiquitin Protein Ligase Antikörper auf antikoerper-online.de

Showing 10 out of 74 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert IHC, WB WB Suggested Anti-UHRF2 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:62500 Positive Control: Jurkat cell lysate Human Heart 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Rind (Kuh) Kaninchen Unkonjugiert WB WB Suggested Anti-UHRF2 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:62500 Positive Control: Human Liver 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Rind (Kuh) Kaninchen Unkonjugiert WB WB Suggested Anti-Uhrf2 Antibody Positive Control: Lane 1: 60ug HCT116 lysate Primary Antibody Dilution : 1:1000 Secondary Antibody : Anti rabbit-HRP Secondry Antibody Dilution : 1:5,000 Submitted by: Chinweike Ukomadu, Brigham and Women's Hospital, Boston WB Suggested Anti-Uhrf2 Antibody Titration: 1.0 ug/ml Positive Control: Mouse Pancreas 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Maus Unkonjugiert IF, WB Western Blot analysis of UHRF2 expression in transfected 293T cell line by UHRF2 monoclonal antibody (M01), clone 3A11. Lane 1: UHRF2 transfected lysate(56.1 KDa). Lane 2: Non-transfected lysate. Western blot analysis of UHRF2 over-expressed 293 cell line, cotransfected with UHRF2 Validated Chimera RNAi used as specificity and loading control. 100 μg Anmelden zum Anzeigen 8 bis 11 Tage
$461.00
Details
Human Kaninchen Unkonjugiert IF, IHC, WB 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$335.00
Details
Human Kaninchen Unkonjugiert IF, IHC, WB Immunohistochemistry of paraffin-embedded human liver cancer using UHRF2 antibody at dilution of 1:200 (400x lens). 100 μL Anmelden zum Anzeigen 16 Days
$334.02
Details
Rind (Kuh) Kaninchen Unkonjugiert IHC, IHC (p), WB 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$551.83
Details
Human Kaninchen Unkonjugiert IHC (p), WB NIRF was detected in paraffin-embedded sections of mouse intestine tissues using rabbit anti- NIRF Antigen Affinity purified polyclonal antibody at 1 μg/mL. The immunohistochemical section was developed using SABC method NIRF was detected in paraffin-embedded sections of rat intestine tissues using rabbit anti- NIRF Antigen Affinity purified polyclonal antibody at 1 μg/mL. The immunohistochemical section was developed using SABC method 100 μg Anmelden zum Anzeigen 4 bis 6 Tage
$280.00
Details
Fledermaus Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$551.83
Details
Human Kaninchen Unkonjugiert IHC, WB Immunohistochemical analysis of NIRF staining in rat heart formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the anti Western blot analysis of NIRF expression in Hela (A), PC3 (B), THP1 (C) whole cell lysates. 200 μL Anmelden zum Anzeigen 13 bis 14 Tage
$487.50
Details

UHRF2 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-Ubiquitin-Like with PHD and Ring Finger Domains 2, E3 Ubiquitin Protein Ligase Antikörper

  1. Cow (Bovine) Polyclonal UHRF2 Primary Antibody für IHC, WB - ABIN2776012 : Liu, Zhu, Zhou, Zhang, Xu, Li: [Analysis of diagnosis and misdiagnosis of pulmonary thromboembolism in emergency]. in Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue 2004 (PubMed)
    Show all 2 Pubmed References

Weitere Antikörper gegen Ubiquitin-Like with PHD and Ring Finger Domains 2, E3 Ubiquitin Protein Ligase Interaktionspartner

Human Ubiquitin-Like with PHD and Ring Finger Domains 2, E3 Ubiquitin Protein Ligase (UHRF2) Interaktionspartner

  1. UHRF2 expression is reduced in some leukemia cell lines, this correlates with promoter hypermethylation, and similar UHRF2 methylation profiles are seen in primary human leukemia samples. Thus, UHRF2 and 5hmC are widely present in differentiated human tissues, and UHRF2 protein is poorly expressed or mislocalized in diverse human cancers.

  2. Here, we report the complex structure of PCNA (zeige PCNA Antikörper) and the peptide ((784)NEILQTLLDLFFPGYSK(800)) derived from UHRF2 that contains a PIP (zeige PIP Antikörper) box. Structural analysis combined with mutagenesis experiments provide the molecular basis for the recognition of UHRF2 by PCNA (zeige PCNA Antikörper) via PIP (zeige PIP Antikörper)-box.

  3. Results show that UHRF2 down-regulates a number of epithelial-mesenchymal transition markers and up-regulates the expression of transcription factors. The study also suggests that UHRF2 play a role in tumor metastasis.

  4. TIP60 (zeige KAT5 Antikörper) acted downstream of UHRF2 to regulate H3K9ac and H3K14ac expression.

  5. The overexpression of UHRF2 increased the expression of H3K9ac in L02 normal cells (P<0.01), but decreased the expression of histone H3 (zeige HIST3H3 Antikörper) lysine 9 acetylation in HepG2 cancer cells.

  6. study suggests that ZNF618 (zeige ZNF618 Antikörper) is a key protein that regulates UHRF2 function as a specific 5hmC reader in vivo.

  7. UHRF2 may contribute to the progression of colon carcinogenesis and function as a novel prognostic indicator after curative operation

  8. A hydrogen bond between the hydroxyl group of 5hmC and UHRF2-SRA (zeige SRA1 Antikörper) is critical for their preferential binding.

  9. UHRF2 is a transcriptional target of E2F (zeige E2F1 Antikörper), that it directly interacts with E2F1 (zeige E2F1 Antikörper).

  10. UHRF2, the homolog of UHRF1 (zeige UHRF1 Antikörper), interacts with N-methylpurine DNA glycosylase (MPG (zeige MPG Antikörper)) in cancer cells.

Mouse (Murine) Ubiquitin-Like with PHD and Ring Finger Domains 2, E3 Ubiquitin Protein Ligase (UHRF2) Interaktionspartner

  1. 5mC levels are decreased at certain genomic loci in the brains of Uhrf2 knockout mice. UHRF KO mice develop frequent spontaneous seizures.

  2. Uhrf2 null mice exhibit a reduction of 5-Hydroxymethylcytosine in the brain, including the cortex and hippocampus. Furthermore, the Uhrf2 null mice exhibit a partial impairment in spatial memory acquisition and retention.

  3. Uhrf2 is highly expressed in aorta and aortic vascular smooth muscle cells.

  4. UHRF2 is not able to rescue the DNA methylation (zeige HELLS Antikörper) defect in Uhrf1 (zeige UHRF1 Antikörper) null mouse embryonic stem cells.

Ubiquitin-Like with PHD and Ring Finger Domains 2, E3 Ubiquitin Protein Ligase (UHRF2) Antigen-Profil

Protein Überblick

This gene encodes a nuclear protein which is involved in cell-cycle regulation. The encoded protein is a ubiquitin-ligase capable of ubiquinating PCNP (PEST-containing nuclear protein), and together they may play a role in tumorigenesis. The encoded protein contains an NIRF_N domain, a PHD finger, a set- and ring-associated (SRA) domain, and a RING finger domain and several of these domains have been shown to be essential for the regulation of cell proliferation. This protein may also have a role in intranuclear degradation of polyglutamine aggregates. Alternative splicing results in multiple transcript variants some of which are non-protein coding.

Genbezeichner und Symbole assoziert mit UHRF2

  • ubiquitin like with PHD and ring finger domains 2 (UHRF2) Antikörper
  • ubiquitin-like, containing PHD and RING finger domains 2 (Uhrf2) Antikörper
  • ubiquitin like with PHD and ring finger domains 2 (Uhrf2) Antikörper
  • 2310065A22Rik Antikörper
  • AI426270 Antikörper
  • AW214556 Antikörper
  • D130071B19Rik Antikörper
  • Nirf Antikörper
  • RNF107 Antikörper
  • URF2 Antikörper

Bezeichner auf Proteinebene für UHRF2

E3 ubiquitin-protein ligase UHRF2 , Np95-like ring finger protein , RING finger protein 107 , np95/ICBP90-like RING finger protein , nuclear protein 97 , nuclear zinc finger protein NP97 , ubiquitin-like PHD and RING finger domain-containing protein 2 , ubiquitin-like, containing PHD and RING finger domains, 2 , ubiquitin-like-containing PHD and RING finger domains protein 2 , nuclear zinc finger protein Np97 , ubiquitin-like, containing PHD and RING finger domains 2

GENE ID SPEZIES
115426 Homo sapiens
474702 Canis lupus familiaris
613759 Bos taurus
109113 Mus musculus
309331 Rattus norvegicus
100715709 Cavia porcellus
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