UHRF2 Antikörper (N-Term)

Produktnummer ABIN2776012

Produktdetails anti-UHRF2 Antikörper

Target: UHRF2 (Ubiquitin-Like with PHD and Ring Finger Domains 2, E3 Ubiquitin Protein Ligase (UHRF2))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Kaninchen, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser UHRF2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: TNKLDSVPST SNSDCVAADE DVIYHIQYDE YPESGTLEMN VKDLRPRART

Homologie: Cow: 86%, Dog: 86%, Guinea Pig: 93%, Horse: 86%, Human: 100%, Mouse: 86%, Rabbit: 100%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against UHRF2. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human UHRF2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 802 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-UHRF2 Antikörper (ABIN2776012)

Liu, Zhu, Zhou, Zhang, Xu, Li: "[Analysis of diagnosis and misdiagnosis of pulmonary thromboembolism in emergency]." in: Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue, Vol. 16, Issue 8, pp. 464-7, (2004) (PubMed).

Details zu UHRF2

Target: UHRF2 (Ubiquitin-Like with PHD and Ring Finger Domains 2, E3 Ubiquitin Protein Ligase (UHRF2))

Andere Bezeichnung: UHRF2 (UHRF2 Produkte)

Synonyme: NIRF antikoerper, RNF107 antikoerper, URF2 antikoerper, 2310065A22Rik antikoerper, AI426270 antikoerper, AW214556 antikoerper, D130071B19Rik antikoerper, Nirf antikoerper, ubiquitin like with PHD and ring finger domains 2 antikoerper, ubiquitin-like, containing PHD and RING finger domains 2 antikoerper, ubiquitin-like with PHD and ring finger domains 2, E3 ubiquitin protein ligase L homeolog antikoerper, UHRF2 antikoerper, Uhrf2 antikoerper, uhrf2.L antikoerper

Hintergrund: UHRF2 encodes a nuclear protein which is involved in cell-cycle regulation. The encoded protein is a ubiquitin-ligase capable of ubiquinating PCNP (PEST-containing nuclear protein), and together they may play a role in tumorigenesis.
Alias Symbols: NIRF, URF2, RNF107, RP11-472F14.2
Protein Interaction Partner: UBE2D1, UBC, TP53, UHRF2, TRIM27, E2F1, MPG, SMAD4, ZNF131, SUMO1, UBE2I, ATXN1, USP7, TWF2, TRIM8, RBCK1, TFAP4, PCNP, CDK2, CCNE1, UHRF1, EHMT2, HIST1H3A, SUMO2, DNMT3B, DNMT3A, DNMT1, CDK1, CD27, CCNB1, CCNA2, BCL2L1, CCND1, BAX, BCAR1, YY1, SKP1, RB1,
Protein Size: 802

Molekulargewicht: 90 kDa

Gen-ID: 115426

NCBI Accession: NM_152896, NP_690856

UniProt: Q96PU4