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USP8 Proteine

Hydrolase that can remove conjugated ubiquitin from proteins and therefore plays an important regulatory role at the level of protein turnover by preventing degradation.

5 Treffer:

Ubiquitin Specific Peptidase 8 (USP8) (AA 1-1118) protein (His tag) Protein

USP8 Spezies: Human Quelle: Insektenzellen Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. Crys, ELISA, SDS, WB
Produktnummer ABIN3096238
$14,592.92
Zzgl. Versandkosten $45.00 und $24.00 Trockeneis
1 mg (More quantities available)
local_shipping Lieferung nach: Vereinigte Staaten von Amerika
Lieferung in 70 Werktagen

Ubiquitin Specific Peptidase 8 (USP8) (AA 777-1118) protein (T7 tag,His tag) Protein

USP8 Spezies: Human Quelle: Escherichia coli (E. coli) Recombinant ≥ 92 % ELISA, IP, SDS, WB
Produktnummer ABIN6237081
$410.00
Zzgl. Versandkosten $45.00
50 μg (More quantities available)
local_shipping Lieferung nach: Vereinigte Staaten von Amerika
Lieferung in 15 bis 18 Werktagen

Ubiquitin Specific Peptidase 8 (USP8) (Transcript Variant 3) protein (Myc-DYKDDDDK Tag) Protein

USP8 Spezies: Human Quelle: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, Func, PI, STD
Produktnummer ABIN2734893
$888.80
Zzgl. Versandkosten $45.00 und $24.00 Trockeneis
20 μg
local_shipping Lieferung nach: Vereinigte Staaten von Amerika
Lieferung in 11 Werktagen

Ubiquitin Specific Peptidase 8 (USP8) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag) Protein

USP8 Spezies: Human Quelle: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, Func, PI, STD
Produktnummer ABIN2735146
$888.80
Zzgl. Versandkosten $45.00 und $24.00 Trockeneis
20 μg
local_shipping Lieferung nach: Vereinigte Staaten von Amerika
Lieferung in 11 Werktagen

Ubiquitin Specific Peptidase 8 (USP8) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag) Protein

USP8 Spezies: Human Quelle: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, Func, PI, STD
Produktnummer ABIN2735145
$932.80
Zzgl. Versandkosten $45.00 und $24.00 Trockeneis
20 μg
local_shipping Lieferung nach: Vereinigte Staaten von Amerika
Lieferung in 11 Werktagen
  • Typ Protein
    • Protein
  • Target Ubiquitin Specific Peptidase 8 (USP8)
    • Ubiquitin Specific Peptidase 8 (USP8)
    • Hemagglutinin (HA)
    • Ribosome Binding Factor A (RBFA)
    • Tumor Necrosis Factor alpha (TNF)
    • S-Adenosyl-Methionine Synthase (METK)
    • Interleukin 6 (IL6)
    • Interferon gamma (IFNG)
    • Hemoglobin beta (HBB)
    • Triosephosphate Isomerase 1 (TPI1)
    • Thymidylate Kinase (Tmk)
    • Interleukin 4 (IL4)
    • Interleukin 1, beta (IL1B)
    • Interleukin 2 (IL2)
    • Uracil-DNA Glycosylase (UNG)
    • Growth Hormone 1 (GH1)
    • Fibroblast Growth Factor 2 (Basic) (FGF2)
    • Lipoyl synthase lipA
    • Interleukin 10 (IL10)
    • KIT Ligand (KITLG)
    • Malate Dehydrogenase (MDH)
    • Insulin-Like Growth Factor 1 (IGF1)
    • Epidermal Growth Factor (EGF)
    • Leptin (LEP)
    • Interleukin 8 (IL8)
    • Interleukin 3 (IL-3)
    • Myoglobin (MB)
    • Queuine tRNA-Ribosyltransferase 1 (QTRT1)
    • serpin Peptidase Inhibitor, Clade E (Nexin, Plasminogen Activator Inhibitor Type 1), Member 1 (SERPINE1)
    • Hemoglobin, alpha 1 (HBA1)
    • phosphatidylserine Decarboxylase (PISD)
    • Interleukin 1 alpha (IL1A)
    • Prolactin (PRL)
    • Interleukin 13 (IL13)
    • CD40 Ligand (CD40LG)
    • Vascular Endothelial Growth Factor A (VEGFA)
    • Chemokine (C-X-C Motif) Ligand 12 (CXCL12)
    • Albumin (ALB)
    • Aspartate Carbamoyltransferase (PYRB)
    • Phosphoglucosamine Mutase (GLMM)
    • Interleukin 15 (IL15)
    • Porphobilinogen Deaminase (HEMC)
    • beta-2-Microglobulin (B2M)
    • Phenylalanyl-tRNA Synthetase, alpha Subunit (FARSA)
    • Chemokine (C-C Motif) Ligand 2 (CCL2)
    • Gp120
    • Adiponectin (ADIPOQ)
    • Colony Stimulating Factor 2 (Granulocyte-Macrophage) (CSF2)
    • Cytidine Monophosphate (UMP-CMP) Kinase 1, Cytosolic (CMPK1)
    • Fibroblast Growth Factor 1 (Acidic) (FGF1)
    • Interleukin 33 (IL33)
    • Chemokine (C-X-C Motif) Ligand 1 (Melanoma Growth Stimulating Activity, Alpha) (CXCL1)
  • Anwendung
    • Antibody Production (AbP)
    • Functional Studies (Func)
    • Protein Interaction (PI)
    • Standard (STD)
    • ELISA
    • SDS-PAGE (SDS)
    • Western Blotting (WB)
    • Immunoprecipitation (IP)
    • Crystallization (Crys)
  • Reaktivität
    • Human
  • Abbildungen verfügbar
  • Wirt
    • HEK-293 Cells
    • Escherichia coli (E. coli)
    • Insektenzellen
  • Bindungsspezifität
    • AA 1-1118
    • AA 777-1118
    • Transcript Variant 1
    • Transcript Variant 2
    • Transcript Variant 3
  • Konjugat
    • Unkonjugiert
    • Myc-DYKDDDDK Tag
    • His tag
    • T7 tag,His tag
  • Protein-Typ
    • Recombinant
  • Format
    • Liquid

USP8 Protein Überblick

Protein Überblick

Hydrolase that can remove conjugated ubiquitin from proteins and therefore plays an important regulatory role at the level of protein turnover by preventing degradation. Converts both 'Lys-48' an 'Lys-63'-linked ubiquitin chains. Catalytic activity is enhanced in the M phase. Involved in cell proliferation. Required to enter into S phase in response to serum stimulation. May regulate T-cell anergy mediated by RNF128 via the formation of a complex containing RNF128 and OTUB1. Probably regulates the stability of STAM2 and RASGRF1. Regulates endosomal ubiquitin dynamics, cargo sorting, membrane traffic at early endosomes, and maintenance of ESCRT-0 stability. The level of protein ubiquitination on endosomes is essential for maintaining the morphology of the organelle. Deubiquitinates EPS15 and controles tyrosine kinase stability. Removes conjugated ubiquitin from EGFR thus regulating EGFR degradation and downstream MAPK signaling. Involved in acrosome biogenesis through interaction with the spermatid ESCRT-0 complex and microtubules. Deubiquitinates BIRC6/bruce and KIF23/MKLP1.

Genbezeichner und Symbole assoziert mit USP8

  • ubiquitin carboxyl-terminal hydrolase 8 (LOC9310109) Antikörper
  • ubiquitin carboxyl-terminal hydrolase 8 (MGYG_00369) Antikörper
  • ubiquitin specific peptidase 8 (USP8) Antikörper
  • ubiquitin specific peptidase 8 (Usp8) Antikörper
  • AI574262 Antikörper
  • AW557536 Antikörper
  • HumORF8 Antikörper
  • mKIAA0055 Antikörper
  • Ubpy Antikörper

Bezeichner auf Proteinebene für USP8

ubiquitin carboxyl-terminal hydrolase 8 , ubiquitin-specific-processing protease 8 , ubiquitin specific peptidase 8 , ubiquitin carboxyl-terminal hydrolase 8-like , deubiquitinating enzyme 8 , hUBPy , ubiquitin isopeptidase Y , ubiquitin specific protease 8 , ubiquitin thioesterase 8 , ubiquitin thiolesterase 8 , putative deubiquitinating enzyme

GENE ID SPEZIES
9310109 Arabidopsis lyrata subsp. lyrata
10031598 Arthroderma gypseum CBS 118893
100408559 Callithrix jacchus
100437819 Pongo abelii
9101 Homo sapiens
296121 Rattus norvegicus
84092 Mus musculus
100157546 Sus scrofa
415451 Gallus gallus
100351436 Oryctolagus cuniculus
100720255 Cavia porcellus

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