anti-Suppressor of Variegation 3-9 Homolog 2 (Drosophila) (SUV39H2) Antikörper

Histone methyltransferase that specifically trimethylates 'Lys-9' of histone H3 using monomethylated H3 'Lys- 9' as substrate. Zusätzlich bieten wir Ihnen SUV39H2 Proteine (8) und und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
SUV39H2 79723 Q9H5I1
SUV39H2 64707 Q9EQQ0
SUV39H2 364785  
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Top anti-SUV39H2 Antikörper auf antikoerper-online.de

Showing 10 out of 123 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB WB Suggested Anti-SUV39H2 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:312500  Positive Control:  HepG2 cell lysate WB Suggested Anti-SUV39H2  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.12500  Positive Control: HepG2 cell lysate 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$319.00
Details
Ratte Ziege Unkonjugiert ELISA, WB Antibody (1µg/ml) staining of Rat Kidney lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Anmelden zum Anzeigen 6 bis 7 Tage
$429.84
Details
Human Kaninchen Unkonjugiert IHC (p), WB The anti-SUV39H2 Pab (ABIN388081) is used in Western blot to detect SUV39H2 in mouse kidney tissue lysate. Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma. HC = hepatocarcinoma 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$385.00
Details
Human Kaninchen Unkonjugiert IP, WB Western blot analysis of SUV39H2 expression in HepG2 (A), A431 (B), HL60 (C) whole cell lysates. 200 μL Anmelden zum Anzeigen 13 bis 14 Tage
$487.50
Details
Human Kaninchen Unkonjugiert IHC (p), WB Western blot analysis of anti-hSUV39H2-K315 Pab (ABIN388082) in 293 and HL60 cell line lysates (35 µg/lane). hSUV39H2-K315(arrow) was detected using the purified polyclonal antibody (1:62 dilution). Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma. HC = hepatocarcinoma 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$385.00
Details
Human Kaninchen Unkonjugiert ELISA, WB Western Blot (WB) analysis of specific cells using KMT1B Polyclonal Antibody. 100 μL Anmelden zum Anzeigen Verfügbar
$363.46
Details
Rind (Kuh) Ziege Unkonjugiert ChIP, EIA, WB AP22371PU-N (1µg/ml) staining of Rat Kidney lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 0.1 mg Anmelden zum Anzeigen 6 bis 8 Tage
$445.50
Details
Meerschweinchen Kaninchen Unkonjugiert WB 100 μL Anmelden zum Anzeigen 11 bis 14 Tage
$581.17
Details
Human Kaninchen Unkonjugiert WB SUV39H2 Antibody (C-term)  western blot analysis in MDA-MB453 cell line lysates (35ug/lane).This demonstrates the SUV39H2 antibody detected the SUV39H2 protein (arrow). 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$385.00
Details
Human Kaninchen Unkonjugiert ELISA, ICC, IF, WB ABIN6275788 staining 293T by IF/ICC. The sample were fixed with PFA and permeabilized in 0.1% Triton X-100,then blocked in 10% serum for 45 minutes at 25¡ãC. The primary antibody was diluted at 1/200 and incubated with the sample for 1 hour at 37¡ãC. An  Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) Ab, diluted at 1/600, was used as the secondary antibod Western blot analysis of extracts from HepG2, using SUV39H2 Antibody. Lane 1 was treated with the antigen-specific peptide. 100 μL Anmelden zum Anzeigen 11 bis 12 Tage
$390.77
Details

Am meisten referenzierte anti-SUV39H2 Antikörper

  1. Human Polyclonal SUV39H2 Primary Antibody für IHC (p), WB - ABIN388081 : Ota, Suzuki, Nishikawa, Otsuki, Sugiyama, Irie, Wakamatsu, Hayashi, Sato, Nagai, Kimura, Makita, Sekine, Obayashi, Nishi, Shibahara, Tanaka, Ishii, Yamamoto, Saito, Kawai, Isono, Nakamura, Nagahari et al.: Complete sequencing and characterization of 21,243 full-length human cDNAs. ... in Nature genetics 2003 (PubMed)
    Show all 5 Pubmed References

  2. Human Polyclonal SUV39H2 Primary Antibody für IHC (p), ELISA - ABIN543394 : Strausberg, Feingold, Grouse, Derge, Klausner, Collins, Wagner, Shenmen, Schuler, Altschul, Zeeberg, Buetow, Schaefer, Bhat, Hopkins, Jordan, Moore, Max, Wang, Hsieh, Diatchenko, Marusina, Farmer et al.: Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. ... in Proceedings of the National Academy of Sciences of the United States of America 2002 (PubMed)
    Show all 2 Pubmed References

  3. Human Polyclonal SUV39H2 Primary Antibody für ELISA - ABIN546973 : Peters, OCarroll, Scherthan, Mechtler, Sauer, Schöfer, Weipoltshammer, Pagani, Lachner, Kohlmaier, Opravil, Doyle, Sibilia, Jenuwein: Loss of the Suv39h histone methyltransferases impairs mammalian heterochromatin and genome stability. in Cell 2001 (PubMed)

Weitere Antikörper gegen SUV39H2 Interaktionspartner

Human Suppressor of Variegation 3-9 Homolog 2 (Drosophila) (SUV39H2) Interaktionspartner

  1. Study revealed that high SUV39H2 expression positively predicted poor prognosis of CRC patients. Moreover, SUV39H2 promoted CRC proliferation in a SLIT1-dependent manner.

  2. Knockdown of SUV39H2 expression by specific siRNAs in human osteosarcoma cell lines markedly suppressed cancer cell growth and caused an increase in the population of cells in G1 phase and induced apoptosis. Overexpression of SUV39H2 promoted cell proliferation, which indicated that SUV39H2 may possess oncogenic activity in human osteosarcoma.

  3. Our finding unveils a novel autoregulatory mechanism of SUV39H2 through lysine automethylation

  4. Our data show that the differential expression of SUV39H1 and SUV39H2 is associated with genomic instability and that the modulation of these HMTases can be an attractive approach to prevent CLL evolution

  5. SUV39H2 functioned cooperatively with MAGE-A11 to increase androgen-dependent AR transcriptional activity.

  6. histone H3 lysine 9 methylation reduction, which may be due to the downregulation of methyltransferase SUV39H2 and the upregulation of demethylase KDM4C, was found in CD4(+) T lymphocytes of Latent autoimmune diabetes in adults patients

  7. data cannot finally exclude H2AX methylation of SUV39H2 in cells, additional experimental evidence is required to validate this claim.

  8. Our results reveal the regulatory mechanism of LSD1 protein through its lysine methylation by SUV39H2 in human cancer cells

  9. We also demonstrate that the N324K mutant in the SET domain of SUV39H2 that has been shown to cause an inherited nasal skin disease in Labrador Retrievers renders SUV39H2 inactive

  10. Expression of JHDM2A was significantly increased but HDAC2, HDAC7, and SUV39H2 were significantly down-regulated in Systemic Sclerosis B cells relative to controls

  11. genetic association studies in a Finnish population with type I diabetes: The minor T allele of exonic SNP rs17353856 in SUV39H2 is associated with diabetic retinopathy (in a larger meta-analysis); thus an genetic variation may be protective.

  12. findings suggest that Suv39H1 and Suv39H2 are key hypoxia-induced methyltransferases; their decline in fetal lung during late gestation is critical for epigenetic changes resulting in the developmental induction of SP-A

  13. a novel SUV39H2 polymorphism may have a role in lung cancer susceptibility for smokers

  14. The SUV39H2 gene is found in tetrapods (e.g., human, mouse and frog) but not in zebrafish, suggesting that this gene is generated by a tetrapod lineage-specific gene duplication event.

Mouse (Murine) Suppressor of Variegation 3-9 Homolog 2 (Drosophila) (SUV39H2) Interaktionspartner

  1. The authors show here that the mouse Suv39h2 enzyme differs from Suv39h1 by containing an N-terminal basic domain that facilitates retention at mitotic chromatin and provides an additional affinity for major satellite repeat RNA.

  2. Data indicate that histone methyltransferase Suv39h2 expression is up-regulated in the liver in liver steatosis.

  3. Repeat-associated, Suv39h-dependent H3K9me3 displays a dynamic distribution that differs in the epigenome of pluripotent versus more committed cells.

  4. ESET histone methyltransferase can form a large, multi-protein complex(es) with mSin3A/B co-repressors and HDAC1/2 that participates in multiple pathways of transcriptional repression.

  5. Taken together, the results indicate epigenetic regulation of telomere length in mammals by Suv39h1 and Suv39h2.

Pig (Porcine) Suppressor of Variegation 3-9 Homolog 2 (Drosophila) (SUV39H2) Interaktionspartner

  1. Knockdown of SUV39H1 and SUV39H2 in embryonic stem-like cells and embryonic fibroblasts increases telomere length.

SUV39H2 Antigen-Profil

Protein Überblick

Histone methyltransferase that specifically trimethylates 'Lys-9' of histone H3 using monomethylated H3 'Lys- 9' as substrate. H3 'Lys-9' trimethylation represents a specific tag for epigenetic transcriptional repression by recruiting HP1 (CBX1, CBX3 and/or CBX5) proteins to methylated histones. Mainly functions in heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin at pericentric and telomere regions. H3 'Lys-9' trimethylation is also required to direct DNA methylation at pericentric repeats. SUV39H1 is targeted to histone H3 via its interaction with RB1 and is involved in many processes (By similarity).

Genbezeichner und Symbole assoziert mit SUV39H2

  • suppressor of variegation 3-9 homolog 2 (SUV39H2) Antikörper
  • suppressor of variegation 3-9 homolog 2 (Drosophila) (Suv39h2) Antikörper
  • suppressor of variegation 3-9 homolog 2 (Suv39h2) Antikörper
  • suppressor of variegation 3-9 homolog 2 (suv39h2) Antikörper
  • suppressor of variegation 3-9 homolog 2 L homeolog (suv39h2.L) Antikörper
  • 4930507K23Rik Antikörper
  • AA536750 Antikörper
  • D030054H19Rik Antikörper
  • D2Ertd544e Antikörper
  • kmt1b Antikörper
  • SUV39H2 Antikörper

Bezeichner auf Proteinebene für SUV39H2

H3-K9-HMTase 2 , histone H3-K9 methyltransferase 2 , histone-lysine N-methyltransferase SUV39H2 , lysine N-methyltransferase 1B , su(var)3-9 homolog 2 , Suv39h histone methyltransferase , suppressor of variegation 3-9 homolog 2 (Drosophila) , histone-lysine N-methyltransferase SUV39H2-like

GENE ID SPEZIES
79723 Homo sapiens
64707 Mus musculus
364785 Rattus norvegicus
426314 Gallus gallus
466014 Pan troglodytes
477995 Canis lupus familiaris
536936 Bos taurus
549262 Xenopus (Silurana) tropicalis
664651 Sus scrofa
697378 Macaca mulatta
100037174 Xenopus laevis
100401513 Callithrix jacchus
100436926 Pongo abelii
100469547 Ailuropoda melanoleuca
100591032 Nomascus leucogenys
100728513 Cavia porcellus
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