SUV39H2 Produkte
(Suppressor of Variegation 3-9 Homolog 2 (Drosophila) (SUV39H2))
Kategorien
Histone methyltransferase that specifically trimethylates 'Lys-9' of histone H3 using monomethylated H3 'Lys- 9' as substrate. H3 'Lys-9' trimethylation represents a specific tag for epigenetic transcriptional repression by recruiting HP1 (CBX1, CBX3 and/or CBX5) proteins to methylated histones. Mainly functions in heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin at pericentric and telomere regions. H3 'Lys-9' trimethylation is also required to direct DNA methylation at pericentric repeats. SUV39H1 is targeted to histone H3 via its interaction with RB1 and is involved in many processes (By similarity).
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Ausgewählte SUV39H2 Kategorien
SUV39H2 Antikörper
High quality antibodies with extensive validation data.
SUV39H2 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene SUV39H2 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
IHC, IF
Validierungen
- (4)
Kat. Nr.
ABIN7075771
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human, Mouse
Applikation
WB, IHC (p)
Validierungen
- (3)
- (3)
Kat. Nr.
ABIN388081
Menge
400 μL
Datenblatt
Datenblatt
Reaktivität
Human, Rat
Applikation
WB, ELISA, IHC
Validierungen
- (5)
Kat. Nr.
ABIN3029054
Menge
0.4 mL
Datenblatt
Datenblatt
Empfohlene SUV39H2 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN6232503
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene SUV39H2 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1321939
Menge
25 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Tobacco (Nicotiana tabacum)
Validierungen
- (1)
Kat. Nr.
ABIN3095760
Menge
1 mg
Datenblatt
Datenblatt
Reaktivität
Mouse
Source
Tobacco (Nicotiana tabacum)
Validierungen
- (1)
Kat. Nr.
ABIN3137192
Menge
1 mg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren SUV39H2 Produkten
: "IFI16, a nuclear innate immune DNA sensor, mediates epigenetic silencing of herpesvirus genomes by its association with H3K9 methyltransferases SUV39H1 and GLP." in: eLife, Vol. 8, (2019) (PubMed).: "Alternative splicing regulates the expression of G9A and SUV39H2 methyltransferases, and dramatically changes SUV39H2 functions." in: Nucleic acids research, Vol. 43, Issue 3, pp. 1869-82, (2015) (PubMed).
: "Histone-modifying genes as biomarkers in hepatocellular carcinoma." in: International journal of clinical and experimental pathology, Vol. 7, Issue 5, pp. 2496-507, (2015) (PubMed).
: "High expressions of histone methylation- and phosphorylation-related proteins are associated with prognosis of oral squamous cell carcinoma in male population of Taiwan." in: Medical oncology (Northwood, London, England), Vol. 30, Issue 2, pp. 513, (2013) (PubMed).
: "Epigenetic regulation of surfactant protein A gene (SP-A) expression in fetal lung reveals a critical role for Suv39h methyltransferases during development and hypoxia." in: Molecular and cellular biology, Vol. 31, Issue 10, pp. 1949-58, (2011) (PubMed).
: "Complete sequencing and characterization of 21,243 full-length human cDNAs. ..." in: Nature genetics, Vol. 36, Issue 1, pp. 40-5, (2003) (PubMed).
: "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. ..." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 26, pp. 16899-903, (2002) (PubMed).
: "Loss of the Suv39h histone methyltransferases impairs mammalian heterochromatin and genome stability." in: Cell, Vol. 107, Issue 3, pp. 323-37, (2001) (PubMed).
: "Regulation of chromatin structure by site-specific histone H3 methyltransferases." in: Nature, Vol. 406, Issue 6796, pp. 593-9, (2000) (PubMed).
: "Isolation and characterization of Suv39h2, a second histone H3 methyltransferase gene that displays testis-specific expression." in: Molecular and cellular biology, Vol. 20, Issue 24, pp. 9423-33, (2000) (PubMed).
Synonyme und alternative Namen zu SUV39H2
suppressor of variegation 3-9 homolog 2 (SUV39H2), suppressor of variegation 3-9 homolog 2 (Drosophila) (Suv39h2), suppressor of variegation 3-9 homolog 2 (Suv39h2), suppressor of variegation 3-9 homolog 2 (suv39h2), suppressor of variegation 3-9 homolog 2 L homeolog (suv39h2.L), 4930507K23Rik, AA536750, D030054H19Rik, D2Ertd544e, KMT1B, kmt1b, SUV39H2Bezeichner auf Proteinebene für SUV39H2
- H3-K9-HMTase 2
- histone H3-K9 methyltransferase 2
- histone-lysine N-methyltransferase SUV39H2
- lysine N-methyltransferase 1B
- su(var)3-9 homolog 2
- Suv39h histone methyltransferase
- suppressor of variegation 3-9 homolog 2 (Drosophila)
- histone-lysine N-methyltransferase SUV39H2-like
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