anti-Sodium Channel, Voltage-Gated, Type III, beta Subunit (SCN3B) Antikörper

Voltage-gated sodium channels are transmembrane glycoprotein complexes composed of a large alpha subunit and one or more regulatory beta subunits. Zusätzlich bieten wir Ihnen Sodium Channel, Voltage-Gated, Type III, beta Subunit Proteine (13) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
SCN3B 235281 Q8BHK2
SCN3B 245956 Q9JK00
SCN3B 55800 Q9NY72
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Top anti-Sodium Channel, Voltage-Gated, Type III, beta Subunit Antikörper auf antikoerper-online.de

Showing 10 out of 75 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB Host: Rabbit Target Name: SCN3B Sample Tissue: Human DLD1 Antibody Dilution: 1.0ug/ml WB Suggested Anti-SCN3B Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:12500 Positive Control: Human brain 100 μL 2 bis 3 Tage
$319.00
Details
Human Kaninchen Unkonjugiert WB WB Image Sample(30 μg of whole cell lysate) A:HeLa S3, B:Hep G2, 12% SDS PAGE antibody diluted at 1:500 100 μL 3 bis 4 Tage
$466.18
Details
Rind (Kuh) Kaninchen Unkonjugiert IHC, IHC (p), WB Brain, cortex Anti-SCN3B antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 1.25 ug/ml. This image was taken for the unconjugated form of this product. ... 100 μL 11 bis 14 Tage
$727.83
Details
Human Maus FITC ICC, IF, WB Immunocytochemistry/Immunofluorescence analysis using Mouse Anti-Nav beta 3 Monoclonal Antibody, Clone S396-29 . Tissue: Neuroblastoma cell line (SK-N-BE). Species: Human. Fixation: 4% Formaldehyde for 15 min at RT. Primary Antibody: Mouse Anti-Nav beta 3 Monoclonal Antibody  at 1:100 for 60 min at RT. Secondary Antibody: Goat Anti-Mouse ATTO 488 at 1:100 for 60 min at RT. Counterstain: Phalloidin Texas Red F-Actin stain; DAPI (blue) nuclear stain at 1:1000, 1:5000 for 60min RT, 5min RT. Localization: Cell Membrane, Nucleus. Magnification: 60X. (A) DAPI (blue) nuclear stain (B) Phalloidin Texas Red F-Actin stain (C) Nav beta 3 Antibody (D) Composite. Western Blot analysis of Mouse Brain showing detection of ~40 kDa Nav Beta 3 protein using Mouse Anti-Nav Beta 3 Monoclonal Antibody, Clone S396-29 . Lane 1: MW Ladder. Lane 2: Mouse Brain. Load: 20 µg. Primary Antibody: Mouse Anti-Nav Beta 3 Monoclonal Antibody  at 1:1000 for 16 hours at 4°C. Secondary Antibody: Goat Anti-Mouse IgG: HRP at 1:200 for 1 hour at RT. Predicted/Observed Size: ~40 kDa. 100 μg 3 bis 4 Tage
$504.40
Details
Human Maus PerCP ICC, IF, WB Immunocytochemistry/Immunofluorescence analysis using Mouse Anti-Nav beta 3 Monoclonal Antibody, Clone S396-29 . Tissue: Neuroblastoma cell line (SK-N-BE). Species: Human. Fixation: 4% Formaldehyde for 15 min at RT. Primary Antibody: Mouse Anti-Nav beta 3 Monoclonal Antibody  at 1:100 for 60 min at RT. Secondary Antibody: Goat Anti-Mouse ATTO 488 at 1:100 for 60 min at RT. Counterstain: Phalloidin Texas Red F-Actin stain; DAPI (blue) nuclear stain at 1:1000, 1:5000 for 60min RT, 5min RT. Localization: Cell Membrane, Nucleus. Magnification: 60X. (A) DAPI (blue) nuclear stain (B) Phalloidin Texas Red F-Actin stain (C) Nav beta 3 Antibody (D) Composite. Western Blot analysis of Mouse Brain showing detection of ~40 kDa Nav Beta 3 protein using Mouse Anti-Nav Beta 3 Monoclonal Antibody, Clone S396-29 . Lane 1: MW Ladder. Lane 2: Mouse Brain. Load: 20 µg. Primary Antibody: Mouse Anti-Nav Beta 3 Monoclonal Antibody  at 1:1000 for 16 hours at 4°C. Secondary Antibody: Goat Anti-Mouse IgG: HRP at 1:200 for 1 hour at RT. Predicted/Observed Size: ~40 kDa. 100 μg 3 bis 4 Tage
$513.50
Details
Human Maus APC ICC, IF, WB Immunocytochemistry/Immunofluorescence analysis using Mouse Anti-Nav beta 3 Monoclonal Antibody, Clone S396-29 . Tissue: Neuroblastoma cell line (SK-N-BE). Species: Human. Fixation: 4% Formaldehyde for 15 min at RT. Primary Antibody: Mouse Anti-Nav beta 3 Monoclonal Antibody  at 1:100 for 60 min at RT. Secondary Antibody: Goat Anti-Mouse ATTO 488 at 1:100 for 60 min at RT. Counterstain: Phalloidin Texas Red F-Actin stain; DAPI (blue) nuclear stain at 1:1000, 1:5000 for 60min RT, 5min RT. Localization: Cell Membrane, Nucleus. Magnification: 60X. (A) DAPI (blue) nuclear stain (B) Phalloidin Texas Red F-Actin stain (C) Nav beta 3 Antibody (D) Composite. Western Blot analysis of Mouse Brain showing detection of ~40 kDa Nav Beta 3 protein using Mouse Anti-Nav Beta 3 Monoclonal Antibody, Clone S396-29 . Lane 1: MW Ladder. Lane 2: Mouse Brain. Load: 20 µg. Primary Antibody: Mouse Anti-Nav Beta 3 Monoclonal Antibody  at 1:1000 for 16 hours at 4°C. Secondary Antibody: Goat Anti-Mouse IgG: HRP at 1:200 for 1 hour at RT. Predicted/Observed Size: ~40 kDa. 100 μg 3 bis 4 Tage
$513.50
Details
Human Maus Atto 655 ICC, IF, WB Immunocytochemistry/Immunofluorescence analysis using Mouse Anti-Nav beta 3 Monoclonal Antibody, Clone S396-29 . Tissue: Neuroblastoma cell line (SK-N-BE). Species: Human. Fixation: 4% Formaldehyde for 15 min at RT. Primary Antibody: Mouse Anti-Nav beta 3 Monoclonal Antibody  at 1:100 for 60 min at RT. Secondary Antibody: Goat Anti-Mouse ATTO 488 at 1:100 for 60 min at RT. Counterstain: Phalloidin Texas Red F-Actin stain; DAPI (blue) nuclear stain at 1:1000, 1:5000 for 60min RT, 5min RT. Localization: Cell Membrane, Nucleus. Magnification: 60X. (A) DAPI (blue) nuclear stain (B) Phalloidin Texas Red F-Actin stain (C) Nav beta 3 Antibody (D) Composite. Western Blot analysis of Mouse Brain showing detection of ~40 kDa Nav Beta 3 protein using Mouse Anti-Nav Beta 3 Monoclonal Antibody, Clone S396-29 . Lane 1: MW Ladder. Lane 2: Mouse Brain. Load: 20 µg. Primary Antibody: Mouse Anti-Nav Beta 3 Monoclonal Antibody  at 1:1000 for 16 hours at 4°C. Secondary Antibody: Goat Anti-Mouse IgG: HRP at 1:200 for 1 hour at RT. Predicted/Observed Size: ~40 kDa. 100 μg 3 bis 4 Tage
$514.80
Details
Human Maus Atto 680 ICC, IF, WB Immunocytochemistry/Immunofluorescence analysis using Mouse Anti-Nav beta 3 Monoclonal Antibody, Clone S396-29 . Tissue: Neuroblastoma cell line (SK-N-BE). Species: Human. Fixation: 4% Formaldehyde for 15 min at RT. Primary Antibody: Mouse Anti-Nav beta 3 Monoclonal Antibody  at 1:100 for 60 min at RT. Secondary Antibody: Goat Anti-Mouse ATTO 488 at 1:100 for 60 min at RT. Counterstain: Phalloidin Texas Red F-Actin stain; DAPI (blue) nuclear stain at 1:1000, 1:5000 for 60min RT, 5min RT. Localization: Cell Membrane, Nucleus. Magnification: 60X. (A) DAPI (blue) nuclear stain (B) Phalloidin Texas Red F-Actin stain (C) Nav beta 3 Antibody (D) Composite. Western Blot analysis of Mouse Brain showing detection of ~40 kDa Nav Beta 3 protein using Mouse Anti-Nav Beta 3 Monoclonal Antibody, Clone S396-29 . Lane 1: MW Ladder. Lane 2: Mouse Brain. Load: 20 µg. Primary Antibody: Mouse Anti-Nav Beta 3 Monoclonal Antibody  at 1:1000 for 16 hours at 4°C. Secondary Antibody: Goat Anti-Mouse IgG: HRP at 1:200 for 1 hour at RT. Predicted/Observed Size: ~40 kDa. 100 μg 3 bis 4 Tage
$514.80
Details
Human Maus Atto 700 ICC, IF, WB Immunocytochemistry/Immunofluorescence analysis using Mouse Anti-Nav beta 3 Monoclonal Antibody, Clone S396-29 . Tissue: Neuroblastoma cell line (SK-N-BE). Species: Human. Fixation: 4% Formaldehyde for 15 min at RT. Primary Antibody: Mouse Anti-Nav beta 3 Monoclonal Antibody  at 1:100 for 60 min at RT. Secondary Antibody: Goat Anti-Mouse ATTO 488 at 1:100 for 60 min at RT. Counterstain: Phalloidin Texas Red F-Actin stain; DAPI (blue) nuclear stain at 1:1000, 1:5000 for 60min RT, 5min RT. Localization: Cell Membrane, Nucleus. Magnification: 60X. (A) DAPI (blue) nuclear stain (B) Phalloidin Texas Red F-Actin stain (C) Nav beta 3 Antibody (D) Composite. Western Blot analysis of Mouse Brain showing detection of ~40 kDa Nav Beta 3 protein using Mouse Anti-Nav Beta 3 Monoclonal Antibody, Clone S396-29 . Lane 1: MW Ladder. Lane 2: Mouse Brain. Load: 20 µg. Primary Antibody: Mouse Anti-Nav Beta 3 Monoclonal Antibody  at 1:1000 for 16 hours at 4°C. Secondary Antibody: Goat Anti-Mouse IgG: HRP at 1:200 for 1 hour at RT. Predicted/Observed Size: ~40 kDa. 100 μg 3 bis 4 Tage
$514.80
Details
Human Maus Atto 633 ICC, IF, WB Immunocytochemistry/Immunofluorescence analysis using Mouse Anti-Nav beta 3 Monoclonal Antibody, Clone S396-29 . Tissue: Neuroblastoma cell line (SK-N-BE). Species: Human. Fixation: 4% Formaldehyde for 15 min at RT. Primary Antibody: Mouse Anti-Nav beta 3 Monoclonal Antibody  at 1:100 for 60 min at RT. Secondary Antibody: Goat Anti-Mouse ATTO 488 at 1:100 for 60 min at RT. Counterstain: Phalloidin Texas Red F-Actin stain; DAPI (blue) nuclear stain at 1:1000, 1:5000 for 60min RT, 5min RT. Localization: Cell Membrane, Nucleus. Magnification: 60X. (A) DAPI (blue) nuclear stain (B) Phalloidin Texas Red F-Actin stain (C) Nav beta 3 Antibody (D) Composite. Western Blot analysis of Mouse Brain showing detection of ~40 kDa Nav Beta 3 protein using Mouse Anti-Nav Beta 3 Monoclonal Antibody, Clone S396-29 . Lane 1: MW Ladder. Lane 2: Mouse Brain. Load: 20 µg. Primary Antibody: Mouse Anti-Nav Beta 3 Monoclonal Antibody  at 1:1000 for 16 hours at 4°C. Secondary Antibody: Goat Anti-Mouse IgG: HRP at 1:200 for 1 hour at RT. Predicted/Observed Size: ~40 kDa. 100 μg 3 bis 4 Tage
$514.80
Details

Am meisten referenzierte anti-Sodium Channel, Voltage-Gated, Type III, beta Subunit Antikörper

  1. Cow (Bovine) Polyclonal SCN3B Primary Antibody für WB - ABIN2780215 : Lazrek, Goffard, Schanen, Karquel, Bocket, Lion, Devaux, Hedouin, Gosset, Hober: Detection of hepatitis C virus antibodies and RNA among medicolegal autopsy cases in Northern France. in Diagnostic microbiology and infectious disease 2006 (PubMed)
    Show all 4 Pubmed References

Weitere Antikörper gegen Sodium Channel, Voltage-Gated, Type III, beta Subunit Interaktionspartner

Mouse (Murine) Sodium Channel, Voltage-Gated, Type III, beta Subunit (SCN3B) Interaktionspartner

  1. beta1-beta3 is more likely to form a di-polymer than beta1-beta1 based on molecular interaction analysis, including potential energy analysis

  2. This study demonistrated that scn3b gene expression in mouse dorsal raphe nucleus

  3. These data suggest that the SOD1G93A mutation results in increased expression of the beta3 subunit of voltage-gated Na+ channels in the spinal cord..

  4. deficiency in Scn3b results in significant atrial electrophysiological and intracardiac conduction abnormalities

  5. SCN3B mediates a p53-dependent apoptotic pathway and may be a candidate for gene therapy combined with anticancer drugs.

  6. Bipolar electrogram and monophasic action potential recordings from the ventricles of Langendorff-perfused Scn3b(-/-) hearts demonstrated ventricular tachycardias induced by programmed electrical stimulation.

Human Sodium Channel, Voltage-Gated, Type III, beta Subunit (SCN3B) Interaktionspartner

  1. Contribution of Cardiac Sodium Channel beta-Subunit Variants to Brugada Syndrome.

  2. In a nonreferred nationwide Danish cohort of SIDS cases, up to 5/66 (7.5%) of SIDS cases can be explained by genetic variants in the sodium channel complex genes.

  3. SCN1-3B the gene that encode respectively a- and b-subunits of the cardiac fast voltage-gated sodium channel, have been linked to atrial fibrillation.

  4. The Val110Ile mutation of SCN3B is a relatively common cause of SCN5A-negative BrS in Japan, which has a reduced sodium current because of the loss of cell surface expression of Nav1.5.

  5. the beta3 subunit can mediate trans homophilic-binding via its Ig domain and the beta3-Ig domain can associate heterophilically with the beta1 subunit

  6. three mutations in SCN3B were investigated electrophysiologically and all led to loss of function in the sodium current, supporting the hypothesis that decreased sodium current enhances atrial fibrillation susceptibility

  7. The researchers found evidence of an association between SCN3B subunit mutations and sudden infant death syndrome pathogenesis.

  8. The sodium channel {beta}3-subunit induces multiphasic gating in NaV1.3 and affects fast inactivation via distinct intracellular regions.

  9. This study identifies the first atrial fibrillation(AF) -associated mutation in SCN3B, and suggests that mutations in SCN3B may be a new pathogenic cause of AF.

  10. Study provides molecular and cellular evidence implicating mutations in SCN3B as a cause of idiopathic ventricular fibrillation.

  11. SCN3B mediates a p53-dependent apoptotic pathway and may be a candidate for gene therapy combined with anticancer drugs.

  12. In patients with temporal lobe epilepsy, Na(v)beta3 levels were dramatically reduced in the hippocampus, but not in the cortex of non-hippocampal sclerosis patients when compared to hippocampal sclerosis patients.

  13. beta3 does not participate in trans homophilic cell-cell adhesion or associate with contactin.

Sodium Channel, Voltage-Gated, Type III, beta Subunit (SCN3B) Antigen-Profil

Protein Überblick

Voltage-gated sodium channels are transmembrane glycoprotein complexes composed of a large alpha subunit and one or more regulatory beta subunits. They are responsible for the generation and propagation of action potentials in neurons and muscle. This gene encodes one member of the sodium channel beta subunit gene family, and influences the inactivation kinetics of the sodium channel. Two alternatively spliced variants, encoding the same protein, have been identified.

Genbezeichner und Symbole assoziert mit SCN3B

  • sodium voltage-gated channel beta subunit 3 (SCN3B) Antikörper
  • sodium channel, voltage-gated, type III, beta (Scn3b) Antikörper
  • sodium voltage-gated channel beta subunit 3 (Scn3b) Antikörper
  • 1110001K16Rik Antikörper
  • 4833414B02Rik Antikörper
  • HSA243396 Antikörper
  • SCNB3 Antikörper

Bezeichner auf Proteinebene für SCN3B

sodium channel subunit beta-3 , brain and heart sodium channel beta 3 subunit , sodium channel beta 3 subunit , voltage-gated sodium channel beta-3 subunit

GENE ID SPEZIES
540925 Bos taurus
235281 Mus musculus
245956 Rattus norvegicus
55800 Homo sapiens
610239 Canis lupus familiaris
100713021 Cavia porcellus
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