anti-Septin 7 (SEPT7) Antikörper

Xenopus laevis Septin 7 (SEPT7) Interaktionspartner

1. study identified control of septin (zeige SEPT6 Antikörper) localization by the planar cell polarity (PCP (zeige PRCP Antikörper)) protein Fritz (zeige WDPCP Antikörper) as a crucial control point for both collective cell movement and ciliogenesis in embryos

Human Septin 7 (SEPT7) Interaktionspartner

1. Study discloses both SEPT2 (zeige SEPT2 Antikörper) and SEPT7 are essential for breast cancer cell migration and invasion by controlling MEK (zeige MAP2K1 Antikörper)/ERK (zeige EPHB2 Antikörper) MAPKs activation.

2. SUMOylation of human septins is critical for septin (zeige SEPT6 Antikörper) filament bundling and cytokinesis.

3. Low SEPT7 expression is associated with glioma cell invasion.

4. Results show that SEPT7 is involved in glioma cell migration with the assistance of cofilin (zeige CFL1 Antikörper) phosphomediated cytoskeleton locomotion.

5. Septin6 and Septin7 GTP binding proteins regulate AP-3- and ESCRT-dependent multivesicular body biogenesis

6. Significantly lower SEPT7 expression in encapsulated follicular variant of papillary thyroid carcinoma may be a sign of different molecular signature in this type of tissue.

7. In response to Candida albicans infection, SEPT7 forms a complex with endothelial cell N-cadherin (zeige CDH2 Antikörper), is required for normal accumulation of N-cadherin (zeige CDH2 Antikörper) around hyphae, and is necessary for maximal fungal endocytosis.

8. SEPT2 (zeige SEPT2 Antikörper) forms a 1:1:1 complex with SEPT7 and SEPT9 (zeige SEPT9 Antikörper).

9. Overexpression of the yeast septin7 ortholog CDC10 also conferred resistance to the negative effects of copper as well as protecting cells from the overexpression of Bax (zeige BAX Antikörper).

10. miR (zeige MLXIP Antikörper)-30a-5p is a bona fide negative regulator of SEPT7 and the oncogenic activity of miR (zeige MLXIP Antikörper)-30a-5p in human gliomas is at least in part through the repression of SEPT7

Horse (Equine) Septin 7 (SEPT7) Interaktionspartner

1. These findings point to a possible pathogenetic role of septin 7 in Equine recurrent uveitis.

Cow (Bovine) Septin 7 (SEPT7) Interaktionspartner

1. a SNP in the CDC10 gene was associated with growth-related traits in Japanese Black beef cattle

Mouse (Murine) Septin 7 (SEPT7) Interaktionspartner

1. SEPT7 regulates gross morphogenesis of the inner ear and maintains the size of the inner ear sensory epithelial area. It does not affect differentiation of hair cells and supporting cells. It exerts its effects at an early developmental stage of the inner ear.

2. Sept7-deficient T cells failed to complete cytokinesis when prompted by pharmacological activation or cytokines. In contrast, cell division was not dependent on sept7 when cell-cell contacts, such as those with antigen-presenting cells, provided a niche.

3. We identified stathmin (zeige STMN1 Antikörper) as a key molecule aiding in septin (zeige SEPT6 Antikörper)-independent cytokinesis, demonstrated that stathmin (zeige STMN1 Antikörper) supplementation is sufficient to override cytokinesis failure in SEPT7-null fibroblasts

4. Sept7 provides a physical scaffold for HDAC6 (zeige HDAC6 Antikörper) to achieve efficient microtubule deacetylation, thereby negatively regulating microtubule stability to an optimal level for neuritogenesis.

5. Septin 7 may regulate meiotic cell cycle progression by affecting microtubule cytoskeletal dynamics in mouse oocytes.

6. Report SEPT4 (zeige SEPT4 Antikörper)/5/7 expression in mouse cochlea and roles in auditory function.

7. performed large-scale interaction screens to understand the neuronal functions of the ERK3 (zeige RYK Antikörper)/MK5 (zeige MAPKAPK5 Antikörper) pathway and identified septin7 (Sept7) as a novel interacting partner of ERK3 (zeige RYK Antikörper)

8. In Sept9 (zeige SEPT9 Antikörper) knockout cells, long septin (zeige SEPT6 Antikörper) filaments stained for Sept7 disappeared. Instead, staining was found in short, often curved filaments and rings. Furthermore, Sept7 was no longer localized to the mitotic spindle

9. SEPT7 is involved in the regulation of subcellular-compartment formation during spermiogenesis in the mouse.