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Malate dehydrogenase catalyzes the reversible oxidation of malate to oxaloacetate, utilizing the NAD/NADH cofactor system in the citric acid cycle. Zusätzlich bieten wir Ihnen Malate Dehydrogenase 1, NAD (Soluble) Antikörper (135) und Malate Dehydrogenase 1, NAD (Soluble) Kits (29) und viele weitere Produktgruppen zu diesem Protein an.
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Data show that in the endogenous readthrough of the human MDH1 stop codon, the stop codon can encode tryptophan and arginine, and is tissue-specific.
Proliferating cells rely on both MDH1 and LDH to replenish cytosolic NAD.
Arginine methylation of MDH1 by CARM1 regulates cellular redox homeostasis and suppresses glutamine metabolism of pancreatic cancer.
adipogenic differentiation may be regulated by the acetylation of MDH1
The MDH1 gene is not the cause of RP28 (zeige FAM161A Proteine)-linked autosomal recessive retinitis pigmentosa.
expression of MDH1 is maintained in the adult heart but is not present in levels as high as in the fetus
Malate Dehydrogenase (zeige ME1 Proteine) directly regulates the Tumor Suppressor Protein p53 (zeige TP53 Proteine)-dependent apoptosis upon glucose deprivation and involved in maintaining cellular metabolic state and further determining cell death.
These findings provide strong evidence that MDH1 plays a critical role in osteoclast differentiation and function via modulation of the intracellular energy status, which might affect AMPK (zeige PRKAA1 Proteine) activity and NFATc1 (zeige NFATC1 Proteine) expression.
Mor2 is an essential factor for oocyte maturation and embryo development in mouse.
Structural features of the alphaB-crystallin (zeige CRYAB Proteine) oligomer when complexed with target proteins under mild stress conditions, i.e., reduction of alpha-lactalbumin (zeige LALBA Proteine) at 37 degrees C and malate dehydrogenase (zeige MDH Proteine) when heated at 42 degrees C, were investigated.
Both immunofluorescence and immunoelectron microscopy demonstrated cMDH at the plasma membrane of LLC-PK(1) cells.
Observations on Mdh1 in both Gpdh (zeige GPD1 Proteine) and Adh (zeige AVP Proteine) backgrounds demonstrate significant increases in ethanol tolerance with partial reductions (50%) in cytosolic MDH (zeige MDH Proteine) activity.
Malate dehydrogenase catalyzes the reversible oxidation of malate to oxaloacetate, utilizing the NAD/NADH cofactor system in the citric acid cycle. The protein encoded by this gene is localized to the cytoplasm and may play pivotal roles in the malate-aspartate shuttle that operates in the metabolic coordination between cytosol and mitochondria. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
cytosolic malate dehydrogenase
, diiodophenylpyruvate reductase
, malate dehydrogenase, cytoplasmic
, soluble malate dehydrogenase
, malate dehydrogenase, soluble
, Malate dehydrogenase-like enzyme
, malate dehydrogenase 1, NAD (soluble)
, malate dehydrogenase 1Ab, cytoplasmic
, malate dehydrogenase 1Ab, peroxisomal
, malate dehydrogenase 1b, NAD (soluble)
, malate dehydrogenase, peroxisomal