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The protein encoded by GEM belongs to the RAD/GEM family of GTP-binding proteins. Zusätzlich bieten wir Ihnen GEM Antikörper (59) und GEM Proteine (5) und viele weitere Produktgruppen zu diesem Protein an.
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Down regulation of Gem expression was involved in the pathogenesis of hepatocellular carcinoma (HCC), and it might be a favorable independent prognostic parameter for HCC.
These findings demonstrate a new role of Gem/Gmip/RhoA signaling in cortical actin regulation during early mitotic stages.
Gem is involved both in T-cell spontaneous cell migration as well as chemotaxis and plays an important role in cell-to-cell HTLV-1 viral transmission.
Data show a mechanism by which GTPase Gem contributes to the mitotic progression by maintaining correct spindle length through the kinesin Kif9.
Gem contains two candidate inhibitory sites, each capable of producing full inhibition of P/Q-type Ca(2 (zeige CA2 ELISA Kits)+) channels.
GEM plays a key role during C. pneumoniae entry into human cells.
We discuss the structural and functional properties of RGK proteins and highlight recent work addressing the mechanism of Gem regulation by calmodulin and 14-3-3 (zeige YWHAQ ELISA Kits).
crystallographic structure and biochemical characterization indicate that Gem G-domain markedly prefers GDP over GTP (zeige AK3 ELISA Kits)
Gem is a bona fide GTPase (zeige RACGAP1 ELISA Kits) that exhibits striking structural and biochemical features that should impact its regulation and cellular activities
Rad, Gem and Rem all reduce depolarization-dependent Ca2 (zeige CA2 ELISA Kits)+ entry in developing myotubes.
These results suggest that Gem plays an important role in normal beta-cell function by regulation of calcium signalling.
Mechanism of the inhibition of calcium channel activity by Gem.
docking of the RGK protein to the nucleotide-kinase domain of the Cavbeta subunit is reminiscent of the binding of GMP (zeige NT5C2 ELISA Kits) to guanylate kinase (zeige GUK1 ELISA Kits)
Results identify specific nuclear localization signals (NLS (zeige ALDH1A2 ELISA Kits)) in Kir/Gem that are both required and sufficient for nuclear transport.
The protein encoded by this gene belongs to the RAD/GEM family of GTP-binding proteins. It is associated with the inner face of the plasma membrane and could play a role as a regulatory protein in receptor-mediated signal transduction. Alternative splicing occurs at this locus and two transcript variants encoding the same protein have been identified.
GTP-binding mitogen-induced T-cell protein
, GTP-binding protein GEM
, GTP-binding protein overexpressed in skeletal muscle
, RAS-like protein KIR
, kinase-inducible Ras-like protein
, GTP binding protein overexpressed in skeletal muscle
, Gem GTPase
, GTP binding protein gene overexpressed in skeletal muscle
, GTP binding protein (gene overexpressed in skeletal muscle)