anti-Folate Hydrolase (Prostate-Specific Membrane Antigen) 1 (FOLH1) Antikörper

FOLH1 encodes a type II transmembrane glycoprotein belonging to the M28 peptidase family. Zusätzlich bieten wir Ihnen PSMA Proteine (23) und PSMA Kits (5) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
FOLH1 2346 Q04609
FOLH1 53320 O35409
FOLH1 85309 P70627
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Top anti-PSMA Antikörper auf antikoerper-online.de

Showing 10 out of 289 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB WB Suggested Anti-FOLH1 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:312500  Positive Control:  Human Placenta 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$319.00
Details
Human Maus Unkonjugiert ICC, IHC (p), WB Immunostaining of a fragment of human GCPII (aminoacids 44-750) produced in S2 cells on Western blot by GCP-04 monoclonal antibody. Lanes 1, 2, 3 represent 800, 400 and 200 pg of the protein. Immunohistochemistry of GCPII in human Medulla oblongata by monoclonal antibody. Mag. 40x; positive astrocytes in white matter. 0.1 mg Anmelden zum Anzeigen 5 bis 7 Tage
$445.99
Details
Human Maus Unkonjugiert FACS, IF, IP 0.1 mg Anmelden zum Anzeigen 6 bis 8 Tage
$313.50
Details
Human Maus Unkonjugiert EIA, IHC (p), WB 0.1 mL Anmelden zum Anzeigen 6 bis 8 Tage
$412.50
Details
Human Maus Unkonjugiert ICC, IF, IHC, IHC (p), WB Immunohistochemistry-Paraffin: PSMA/FOLH1/NAALADase I Antibody (GCP-04) [NBP1-45057] - GCPII in porcine kidney by GCP-04 monoclonal antibody. Highly positive proximal glomeruli. Western Blot: PSMA/FOLH1/NAALADase I Antibody (GCP-04) [NBP1-45057] - Fragment of human GCPII (aminoacids 44-750) produced in S2 cells on Western blot by GCP-04 monoclonal antibody. Lanes 1, 2, 3 represent 800, 400 and 200 pg of the protein. 0.1 mg Anmelden zum Anzeigen 7 bis 9 Tage
$446.35
Details
Human Kaninchen Unkonjugiert ICC, IF, IHC, IHC (p) Immunohistochemistry-Paraffin: PSMA/FOLH1/NAALADase I Antibody [NBP1-89822] - Staining of human prostate shows strong cytoplasmic positivity in glandular cells. Immunocytochemistry/Immunofluorescence: PSMA/FOLH1/NAALADase I Antibody [NBP1-89822] - Staining of human cell line A-431 shows positivity in nucleus but not nucleoli & cytoplasm. 0.1 mL Anmelden zum Anzeigen 10 bis 13 Tage
$494.38
Details
Human Maus Unkonjugiert CyTOF, FACS, ICC, IF, IP Flow Cytometry: PSMA/FOLH1/NAALADase I Antibody (GCP-05) [NBP1-45058] - Analysis of GCPII (PSMA) by various monoclonal antibodies (GCP-01, GCP-02, GCP-04, GCP-05) on LNCaP cell line. Legend: Green column - 1 ug/ml, LNCaP cell line Blue column - 5 ug/ml, LNCaP cell line Yellow column - negative cell line Flow Cytometry: PSMA/FOLH1/NAALADase I Antibody (GCP-05)  - Flow Cytometry: PSMA/FOLH1/NAALADase I Antibody (GCP-05)   - Surface staining (mass cytometry) of LNCaP cell line using anti-GCPII (GCP-05) 173Yb. Gated on singlets. Image using the PE form of this antibody. 0.1 mg Anmelden zum Anzeigen 12 bis 15 Tage
$418.10
Details
Rind (Kuh) Kaninchen Unkonjugiert WB Host:  Rabbit  Target Name:  FOLH1  Sample Type:  RPMI-8226 Whole cell lysates  Antibody Dilution:  1.0ug/ml 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Maus Unkonjugiert IHC, IHC (p), WB Anti-PSMA antibody IHC staining of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN1101606 dilution 10 ug/ml. Anti-PSMA antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 10 ug/ml. 50 μg Anmelden zum Anzeigen 11 bis 14 Tage
$742.50
Details
Human Maus FITC FACS 50 μg Anmelden zum Anzeigen 6 bis 8 Tage
$423.50
Details

Am meisten referenzierte anti-PSMA Antikörper

  1. Human Monoclonal PSMA Primary Antibody für ICC, IHC (p) - ABIN1302364 : Gao, Xu, Cui, Zhang, Lin, Cai, Wang, Luo, Zheng, Wang, Luo, Jiang, Neale, Zhong: Mice lacking glutamate carboxypeptidase II develop normally, but are less susceptible to traumatic brain injury. in Journal of neurochemistry 2015 (PubMed)
    Show all 7 Pubmed References

  2. Human Monoclonal PSMA Primary Antibody für ICC, IF - ABIN4348206 : Barinka, Rinnová, Sácha, Rojas, Majer, Slusher, Konvalinka: Substrate specificity, inhibition and enzymological analysis of recombinant human glutamate carboxypeptidase II. in Journal of neurochemistry 2002 (PubMed)
    Show all 5 Pubmed References

  3. Human Monoclonal PSMA Primary Antibody für FACS, ICC - ABIN457366 : Sácha, Zámecník, Barinka, Hlouchová, Vícha, Mlcochová, Hilgert, Eckschlager, Konvalinka: Expression of glutamate carboxypeptidase II in human brain. in Neuroscience 2007 (PubMed)
    Show all 4 Pubmed References

  4. Human Monoclonal PSMA Primary Antibody für FACS, IF - ABIN238408 : Barinka, Mlcochová, Sácha, Hilgert, Majer, Slusher, Horejsí, Konvalinka: Amino acids at the N- and C-termini of human glutamate carboxypeptidase II are required for enzymatic activity and proper folding. in European journal of biochemistry / FEBS 2004 (PubMed)
    Show all 7 Pubmed References

  5. Human Monoclonal PSMA Primary Antibody für ICC, FACS - ABIN302088 : Tykvart, Navrátil, Sedlák, Corey, Colombatti, Fracasso, Koukolík, Ba?inka, Sácha, Konvalinka: Comparative analysis of monoclonal antibodies against prostate-specific membrane antigen (PSMA). in The Prostate 2014 (PubMed)
    Show all 3 Pubmed References

  6. Human Monoclonal PSMA Primary Antibody für ELISA, WB - ABIN532984 : Slovin: Targeting novel antigens for prostate cancer treatment: focus on prostate-specific membrane antigen. in Expert opinion on therapeutic targets 2005 (PubMed)
    Show all 3 Pubmed References

  7. Human Monoclonal PSMA Primary Antibody für FACS, IF - ABIN535252 : Sulimenko, Dráberová, Sulimenko, Macurek, Richterová, Dráber, Dráber: Regulation of microtubule formation in activated mast cells by complexes of gamma-tubulin with Fyn and Syk kinases. in Journal of immunology (Baltimore, Md. : 1950) 2006 (PubMed)
    Show all 3 Pubmed References

  8. Human Polyclonal PSMA Primary Antibody für ICC, IF - ABIN4348209 : Jaraj, Augsten, Häggarth, Wester, Pontén, Ostman, Egevad: GAD1 is a biomarker for benign and malignant prostatic tissue. in Scandinavian journal of urology and nephrology 2011 (PubMed)
    Show all 2 Pubmed References

  9. Human Monoclonal PSMA Primary Antibody für IF, IHC (p) - ABIN535251 : Diehl, Cheng, Roussel, Sherr: Glycogen synthase kinase-3beta regulates cyclin D1 proteolysis and subcellular localization. in Genes & development 1999 (PubMed)
    Show all 3 Pubmed References

  10. Human Monoclonal PSMA Primary Antibody für IHC (fro), IF - ABIN535893 : Zhu, Zhong, Xu, Lin, Ye, Ji, Sun, Yeh: PSMA mimotope isolated from phage displayed peptide library can induce PSMA specific immune response. in Cell research 2000 (PubMed)
    Show all 2 Pubmed References

Weitere Antikörper gegen PSMA Interaktionspartner

Human Folate Hydrolase (Prostate-Specific Membrane Antigen) 1 (FOLH1) Interaktionspartner

  1. PSMA, TERT, and PDEF may serve as a reference for clinical diagnosis and as potential targets for the malignant tumor of the prostate therapeutics

  2. Furthermore, the results also demonstrate that the stability of GCPII protein is regulated by HDAC1 through acetylation at the lysine 479 residue.

  3. Results provide evidence that PSMA is expressed in the neovasculature of a subset of soft tissue tumors to a variable extent predominantly occurring in sarcomas.

  4. PSMA is significantly overexpressed in the neovasculature of differentiated thyroid cancers compared with normal and benign thyroid nodules

  5. Demonstrate that several laminin-derived peptides containing carboxy-terminal glutamate moieties (LQE, IEE, LNE) are bona fide substrates for PSMA. Subsequently, the peptide products were tested for their effects on angiogenesis in various models.

  6. results demonstrate both the feasibility of preparing PSMA-targeted MBs and the benefits of using bioorthogonal chemistry to create targeted US probes

  7. Xenografted human tumors expressing different levels of prostate-specific membrane antigen (PSMA) was produced to assess the clearance, biodistribution and imaging potential of 123I-scFvD2B.

  8. GCPII may not be a priority target for molecular imaging of atherosclerotic lesions.

  9. We also confirmed the specificity and selectivity of prostate-specific membrane antigen targeting by assessing prostate-specific membrane antigen-null PC3 cell lines under the same conditions (<10% cell ablation

  10. In conclusion, we have successfully developed the specific PSMA-targeting IO nanoparticle, DOTA-IO-GUL, as a dual-modality probe for complementary PET/MR imaging

  11. The risk of coronary disease and ischemic stroke associated with multiple polymorphisms and haplotypes of MADD and FOLH1 in Han Chinese patients are reported in association with alcohol consumption.

  12. MDM2 and PSMA may co-regulate the expression of certain MMPs and, thus, the functionality of cells in metastatic breast cancer.

  13. Systemic treatment with these radiation-sensitizing agents selectively enhanced the potency of external beam radiation therapy for established PSMA-positive tumors.

  14. prostate-specific membrane antigen is significantly overexpressed in adrenocortical carcinoma neovasculature when compared with normal and benign adrenal tumors

  15. Data show that the expressed antibody could specifically bind to prostate-specific membrane antigen ( PSMA) positive cells.

  16. Ad5/35E1aPSESE4 is effective in marking PSA/PSMA-positive prostate cancer cells in patient blood to improve the efficacy of utilizing CTCs as a biomarker.

  17. evaluated the relaxometric properties of these agents in solution, in prostate cancer cells, and in an in vivo experimental model to demonstrate the feasibility of PSMA-based MR molecular imaging

  18. First evidence of PSMA expression in differentiated thyroid cancer using [Ga]PSMA-HBED-CC PET/CT.

  19. In vitro immunotherapy is described for anti-prostate cancer effects of cytotoxic T lymphocytes induction by recombinant adenovirus mediated PSMA/4-1BBL dendritic cells.

  20. Results from genetic models highlight the importance of GCPII genetic variants as relatively novel risk factors for breast cancer and prostate cancer.

Pig (Porcine) Folate Hydrolase (Prostate-Specific Membrane Antigen) 1 (FOLH1) Interaktionspartner

  1. Tissues such as prostate and testes exhibit different GCPII expression levels among the species studied (human, rats, swine).

  2. intestinal GCPII and intestinal and hepatic RFC all exhibit ontogenic changes in the pig that are reflected in postnatal folate status

Mouse (Murine) Folate Hydrolase (Prostate-Specific Membrane Antigen) 1 (FOLH1) Interaktionspartner

  1. Data support the hypothesis that the neuroprotective efficacy of glutamate carboxypeptidase II knockout in traumatic brain injury is mediated via a reduction in oxidative stress.

  2. Knockout of the GCPII gene is not embryonic lethal and affords histopathological protection with improved long-term behavioral outcomes after traumatic brain injury

  3. Inhibition of glutamate carboxypeptidase II (GCPII) activity as a treatment for cognitive impairment in multiple sclerosis.

  4. PSMA plays a VEGF-independent role in retinal angiogenesis

  5. The combined effects of a haplo-insufficiency of glutamate carboxypeptidase II and dietary folic acid deficiency esult in reciprocal protection against cognitive and social deficits.

  6. analysis of GCP2 and GCP3; beta-citrylglutamate hydrolase is glutamate carboxypeptidase 3

  7. active PSMA facilitates integrin signaling and PAK activation, leading to both productive invasion and downregulation of integrin beta(1) signaling via reduced PSMA activity

  8. This study demenestrated that the heterozygous mice,glutamate carboxypeptidase II, however, developed normally to adulthood and exhibited increased locomotor activity, reduced social interaction, and a subtle cognitive deficit in working memory.

PSMA (FOLH1) Antigen-Profil

Protein Überblick

This gene encodes a type II transmembrane glycoprotein belonging to the M28 peptidase family. The protein acts as a glutamate carboxypeptidase on different alternative substrates, including the nutrient folate and the neuropeptide N-acetyl-l-aspartyl-l-glutamate and is expressed in a number of tissues such as prostate, central and peripheral nervous system and kidney. A mutation in this gene may be associated with impaired intestinal absorption of dietary folates, resulting in low blood folate levels and consequent hyperhomocysteinemia. Expression of this protein in the brain may be involved in a number of pathological conditions associated with glutamate excitotoxicity. In the prostate the protein is up-regulated in cancerous cells and is used as an effective diagnostic and prognostic indicator of prostate cancer. This gene likely arose from a duplication event of a nearby chromosomal region. Alternative splicing gives rise to multiple transcript variants encoding several different isoforms.

Genbezeichner und Symbole assoziert mit FOLH1

  • putative N-acetylated-alpha-linked acidic dipeptidase (LOC451185) Antikörper
  • folate hydrolase 1B (FOLH1B) Antikörper
  • folate hydrolase 1 (FOLH1) Antikörper
  • folate hydrolase (prostate-specific membrane antigen) 1 (FOLH1) Antikörper
  • folate hydrolase 1 (Folh1) Antikörper
  • FGCP Antikörper
  • FOLH Antikörper
  • GCP2 Antikörper
  • GCPII Antikörper
  • mGCP Antikörper
  • mopsm Antikörper
  • Naalad Antikörper
  • NAALAD1 Antikörper
  • NAALAdase Antikörper
  • PSM Antikörper
  • PSMA Antikörper

Bezeichner auf Proteinebene für FOLH1

folate hydrolase 1 , glutamate carboxypeptidase 2 , folate hydrolase (prostate-specific membrane antigen) 1 , glutamate carboxypeptidase 2-like , N-acetylated alpha-linked acidic dipeptidase 1 , N-acetylated-alpha-linked acidic dipeptidase I , NAALADase I , cell growth-inhibiting gene 27 protein , folylpoly-gamma-glutamate carboxypeptidase , glutamate carboxylase II , glutamate carboxypeptidase II , membrane glutamate carboxypeptidase , prostate specific membrane antigen variant F , pteroylpoly-gamma-glutamate carboxypeptidase , FGCP , GCPII , mGCP , prostate-specific membrane antigen homolog , prostate-specific membrane antigen , N-acetylated alpha-linked acidic dipeptidase

GENE ID SPEZIES
451185 Pan troglodytes
707714 Macaca mulatta
100396945 Callithrix jacchus
100453848 Pongo abelii
2346 Homo sapiens
419011 Gallus gallus
397677 Sus scrofa
505865 Bos taurus
476775 Canis lupus familiaris
53320 Mus musculus
85309 Rattus norvegicus
Ausgewählte Anbieter für anti-PSMA (FOLH1) Antikörper
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