anti-C-Type Lectin Domain Family 4, Member M (CLEC4M) Antikörper

CLEC4M encodes a transmembrane receptor and is often referred to as L-SIGN because of its expression in the endothelial cells of the lymph nodes and liver. Zusätzlich bieten wir Ihnen C-Type Lectin Domain Family 4, Member M Proteine (10) und C-Type Lectin Domain Family 4, Member M Kits (2) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
CLEC4M 10332 Q9H2X3
CLEC4M    
CLEC4M    
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Top anti-C-Type Lectin Domain Family 4, Member M Antikörper auf antikoerper-online.de

Showing 10 out of 64 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert WB WB Suggested Anti-CLEC4M Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:312500  Positive Control:  Human Muscle 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
€251.30
Details
Pferd Kaninchen Unkonjugiert WB WB Suggested Anti-CLEC4M Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:62500  Positive Control:  MCF7 cell lysate WB Suggested Anti-CLEC4M <br /> Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.2500 <br /> Positive Control: MCF7 cell lysate 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
€251.30
Details
Human Kaninchen Unkonjugiert WB <b>WB Suggested Anti-CLEC4M Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:1562500<br><b>Positive Control: </b>Human kidney WB Suggested Anti-CLEC4M Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:1562500  Positive Control:  Human kidney 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
€251.30
Details
Human Kaninchen Unkonjugiert IHC, WB WB Suggested Anti-CLEC4M Antibody Titration:  1.25ug/ml  Positive Control:  HepG2 cell lysate Human kidney 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
€199.13
Details
Human Maus Unkonjugiert BR, CyTOF, FACS Detection of DC-SIGNR/CD299 in Human DC-SIGNR/CD299 Transfected 3T3 Mouse Cell Line by Flow Cytometry. 500 μg Anmelden zum Anzeigen 8 bis 9 Tage
€342.00
Details
Human Kaninchen Unkonjugiert WB Western blot analysis of CD299 expression in HEK293T (A), Hela (B), NIH3T3 (C), mouse lung (D), mouse heart (E) whole cell lysates. 200 μL Anmelden zum Anzeigen 13 bis 14 Tage
€423.91
Details
Human Maus PE FACS Detection of DC-SIGNR/CD299 in 3T3 Mouse Cell Line Transfected with Human DC-SIGNR/CD299 by Flow Cytometry. 3T3 mouse embryonic fibroblast cell line transfected with human DC-SIGNR/CD299 was stained with Mouse Anti-Human DC-SIGNR/CD299 PE-conjugated Monoclonal Antibody. 100 Tests Anmelden zum Anzeigen 8 bis 9 Tage
€286.00
Details
Human Kaninchen Unkonjugiert ICC, IHC, WB Figure. Western Blot; Sample: Human Serum. 100 μg Anmelden zum Anzeigen 13 bis 16 Tage
€288.70
Details
Human Kaninchen Unkonjugiert IHC, IHC (p), WB 100 μg Anmelden zum Anzeigen 7 bis 9 Tage
€428.84
Details
Human Kaninchen Unkonjugiert ELISA, IHC (p), WB   100 μL Anmelden zum Anzeigen 16 Days
€158.02
Details

CLEC4M Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
Human , , , ,
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Mouse (Murine)


Rat (Rattus)


Am meisten referenzierte anti-C-Type Lectin Domain Family 4, Member M Antikörper

  1. Human Monoclonal CLEC4M Primary Antibody für BR, CyTOF - ABIN5012885 : Ludwig, Lekkerkerker, Depla, Bosman, Musters, Depraetere, van Kooyk, Geijtenbeek: Hepatitis C virus targets DC-SIGN and L-SIGN to escape lysosomal degradation. in Journal of virology 2004 (PubMed)
    Show all 7 Pubmed References

  2. Human Monoclonal CLEC4M Primary Antibody für FACS - ABIN4898522 : Mukherjee, Dowd, Manhart, Ledgerwood, Durbin, Whitehead, Pierson: Mechanism and significance of cell type-dependent neutralization of flaviviruses. in Journal of virology 2014 (PubMed)
    Show all 3 Pubmed References

Weitere Antikörper gegen C-Type Lectin Domain Family 4, Member M Interaktionspartner

Human C-Type Lectin Domain Family 4, Member M (CLEC4M) Interaktionspartner

  1. heterozygous VNTR genotypes 57 and 67 of CLEC4M were highly enriched and are the most likely mechanism through which CLEC4M contributes to disease in the Swedish type 1 VWD (zeige VWF Antikörper) population

  2. DC-SIGNR promoted gastric cancer liver metastasis mediated with HNRNPKP2 which expression was regulated by STAT5A (zeige STAT5A Antikörper). And HNRNPKP2 decreased the expression of downstream target gene CXCR4 (zeige CXCR4 Antikörper). These findings indicated potential therapeutic candidates for gastric cancer liver metastasis.

  3. the neck domains of DC-SIGN (zeige CD209 Antikörper) and DC-SIGNR can contribute to the different functions of these receptors by presenting the sugar-binding sites in different contexts.

  4. Together, these studies confirm a role for C-type lectin (zeige MBL2 Antikörper) receptors DC-SIGN (zeige CD209 Antikörper) and L-SIGN as attachment factors and entry receptors for human metapneumovirus infection.

  5. DC-SIGNR VNTR and DC-SIGN (zeige CD209 Antikörper) VNTR were not associated with the risk of pulmonary tuberculosis in a sample of Iranian population

  6. CD209L variation may influence susceptibility to HIV-1, response to treatment, and disease progression.

  7. DC-SIGNR expression in peripheral blood mononuclear cells was higher in HIV-1-infected patients, and its positive correlation with viral load and negative with CD4 (zeige CD4 Antikörper)+ T cells counts suggest a potential role of DC-SIGNR in HIV-1 infection.

  8. Study demonstrated that serum levels of DC-SIGNR in lung cancer patients were significantly lower than those in healthy individuals, and correlated significantly with brain metastasis and serum NK cells percentage.

  9. Genetic variations in STXBP5 (zeige STXBP5 Antikörper) and CLEC4M are associated with VWF (zeige VWF Antikörper) level variation in type 1, but not in type 2 von Willebrand disease.

  10. of an association between CD209 (zeige CD209 Antikörper) and CD209L polymorphisms and tuberculosis development in a Brazilian population

C-Type Lectin Domain Family 4, Member M (CLEC4M) Antigen-Profil

Protein Überblick

This gene encodes a transmembrane receptor and is often referred to as L-SIGN because of its expression in the endothelial cells of the lymph nodes and liver. The encoded protein is involved in the innate immune system and recognizes numerous evolutionarily divergent pathogens ranging from parasites to viruses, with a large impact on public health. The protein is organized into three distinct domains: an N-terminal transmembrane domain, a tandem-repeat neck domain and C-type lectin carbohydrate recognition domain. The extracellular region consisting of the C-type lectin and neck domains has a dual function as a pathogen recognition receptor and a cell adhesion receptor by binding carbohydrate ligands on the surface of microbes and endogenous cells. The neck region is important for homo-oligomerization which allows the receptor to bind multivalent ligands with high avidity. Variations in the number of 23 amino acid repeats in the neck domain of this protein are common and have a significant impact on ligand binding ability. This gene is closely related in terms of both sequence and function to a neighboring gene (GeneID 30835\; often referred to as DC-SIGN or CD209). DC-SIGN and L-SIGN differ in their ligand-binding properties and distribution. Alternative splicing results in multiple variants.

Genbezeichner und Symbole assoziert mit CLEC4M

  • C-type lectin domain family 4 member M (CLEC4M) Antikörper
  • CD209B Antikörper
  • CD209L Antikörper
  • CD299 Antikörper
  • DC-SIGN2 Antikörper
  • DC-SIGNR Antikörper
  • DCSIGNR Antikörper
  • HP10347 Antikörper
  • L-SIGN Antikörper
  • LSIGN Antikörper

Bezeichner auf Proteinebene für CLEC4M

C-type lectin domain family 4 member M , CD209 antigen-like protein 1 , CD299 antigen , DC-SIGN-related protein , dendritic cell-specific ICAM-3-grabbing non-integrin 2 , liver/lymph node-specific ICAM-3 grabbing non-integrin , liver/lymph node-specific ICAM-3-grabbing non-integrin , mannose binding C-type lectin DC-SIGNR , CD209b antigen

GENE ID SPEZIES
10332 Homo sapiens
455661 Pan troglodytes
Ausgewählte Anbieter für anti-C-Type Lectin Domain Family 4, Member M (CLEC4M) Antikörper
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