C-Type Lectin Domain Family 4, Member M (CLEC4M) (N-Term) Antikörper
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- Target Alle C-Type Lectin Domain Family 4, Member M (CLEC4M) Antikörper anzeigen
- C-Type Lectin Domain Family 4, Member M (CLEC4M)
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Bindungsspezifität
- N-Term
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Reaktivität
- Human, Schwein
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC)
- Sequenz
- LVLQLLSFML LAGVLVAILV QVSKVPSSLS QEQSEQDAIY QNLTQLKAAV
- Homologie
- Human: 100%, Pig: 86%
- Produktmerkmale
- This is a rabbit polyclonal antibody against CLEC4M. It was validated on Western Blot and immunohistochemistry.
- Aufreinigung
- Protein A purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human CLEC4M
- Top Product
- Discover our top product CLEC4M Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 399 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- C-Type Lectin Domain Family 4, Member M (CLEC4M)
- Andere Bezeichnung
- CLEC4M (CLEC4M Produkte)
- Synonyme
- CD209L antikoerper, CD299 antikoerper, DC-SIGN2 antikoerper, DC-SIGNR antikoerper, DCSIGNR antikoerper, HP10347 antikoerper, L-SIGN antikoerper, LSIGN antikoerper, CD209B antikoerper, C-type lectin domain family 4 member M antikoerper, CLEC4M antikoerper
- Hintergrund
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CLEC4M is a type II integral membrane protein that is 77 % identical to CD209 antigen, a HIV gp120-binding protein. This protein, like CD209, efficiently binds both intercellular adhesion molecule 3 (ICAM3) and HIV-1 gp120, and enhances HIV-1 infection of T cells.Western blots using two different antibodies against two unique regions of this protein target confirm the same apparent molecular weight in our tests.This gene encodes a type II integral membrane protein that is 77 % identical to CD209 antigen, a HIV gp120-binding protein. This protein, like CD209, efficiently binds both intercellular adhesion molecule 3 (ICAM3) and HIV-1 gp120, and enhances HIV-1 infection of T cells. This gene is mapped to 19p13.3, in a cluster with the CD209 and CD23/FCER2 genes. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined.
Alias Symbols: CD209L, CD299, DC-SIGN2, DC-SIGNR, DCSIGNR, HP10347, L-SIGN, LSIGN, MGC129964, MGC47866
Protein Interaction Partner: TLR2, MME, CLEC4M, CD209, ICAM3, ITGAM, AP2M1, HCVgp1,
Protein Size: 399 - Molekulargewicht
- 44 kDa
- Gen-ID
- 10332
- NCBI Accession
- NM_014257, NP_055072
- UniProt
- Q9H2X3
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