anti-BMX Non-Receptor Tyrosine Kinase (BMX) Antikörper

BMX encodes a non-receptor tyrosine kinase belonging to the Tec kinase family. Zusätzlich bieten wir Ihnen BMX Proteine (13) und BMX Kits (7) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
BMX 660 P51813
BMX 12169 P97504
BMX 367786  
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Top anti-BMX Antikörper auf antikoerper-online.de

Showing 10 out of 188 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Lieferzeit Preis Details
Human Kaninchen Unkonjugiert IC, IF, IP, IHC, WB Immunofluorescent analysis of BMX staining in A549 cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 °C in a hidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue). Immunohistochemical analysis of BMX staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugad compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. w 200 μL 13 bis 14 Tage
$487.50
Details
Human Kaninchen Unkonjugiert IC, IF, IHC, WB Immunofluorescent analysis of BMX (pY566) staining in HeLa cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 °C in a hidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue). Immunohistochemical analysis of BMX (pY566) staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugad compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. 200 μL 13 bis 14 Tage
$575.00
Details
Human Kaninchen Unkonjugiert WB Western blot analysis of BMX (pY40) expression in MCF7 IL1b-treated (A), Jurkat CD3-treated (B), Raw264.7 IL1b-treated (C), H9C2 IL1b-treated (D) whole cell lysates. 200 μL 13 bis 14 Tage
$575.00
Details
Human Kaninchen Unkonjugiert WB Western blot anlaysis of Etk expression in rat kidney tissue lysate. 100 μg 2 bis 3 Tage
$245.00
Details
Human Kaninchen Unkonjugiert IF, IHC, ELISA, WB Western blot analysis of extracts from COS7 cells, using BMX Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human thyroid gland tissue, using BMX Antibody. The picture on the right is treated with the synthesized peptide. 100 μg 2 bis 3 Tage
$302.50
Details
Human Kaninchen Unkonjugiert IC, IF, IHC, WB   200 μL 13 bis 14 Tage
$487.50
Details
Rind (Kuh) Kaninchen Unkonjugiert IC, IF, IHC, WB   200 μL 13 bis 14 Tage
$487.50
Details
Human Kaninchen Unkonjugiert ELISA, ICC, IF, IHC, WB ABIN6269280 staining HepG2 by IF/ICC. The sample were fixed with PFA and permeabilized in 0.1% Triton X-100,then blocked in 10% serum for 45 minutes at 25°C. The primary antibody was diluted at 1/200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) Ab, diluted at 1/600, was used as the secondary antibody. Western blot analysis of ETK expression in A549 whole cell lysates,The lane on the left is treated with the antigen-specific peptide. 100 μL 11 bis 12 Tage
$390.77
Details
Human Kaninchen Unkonjugiert EIA, IF, IHC (p), WB Immunofluorescence analysis of A549 cells, using BMX Antibody. The picture on the right is treated with the synthesized peptide. Human Intestine, Vessels: Formalin-Fixed, Paraffin-Embedded (FFPE). 50 μL 11 bis 13 Tage
$768.40
Details
Human Kaninchen Unkonjugiert IF, IHC, ELISA, WB Western blot analysis of extracts from A549 cells, using ETK (Ab-566) Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human thyroid gland tissue, using ETK (Ab-566) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg 2 bis 3 Tage
$302.50
Details

Am meisten referenzierte anti-BMX Antikörper

  1. Human Polyclonal BMX Primary Antibody für IHC - ABIN965689 : Tamagnone, Lahtinen, Mustonen, Virtaneva, Francis, Muscatelli, Alitalo, Smith, Larsson, Alitalo: BMX, a novel nonreceptor tyrosine kinase gene of the BTK/ITK/TEC/TXK family located in chromosome Xp22.2. in Oncogene 1994 (PubMed)
    Show all 4 Pubmed References

  2. Human Polyclonal BMX Primary Antibody für IHC - ABIN965688 : Qiu, Robinson, Pretlow, Kung et al.: Etk/Bmx, a tyrosine kinase with a pleckstrin-homology domain, is an effector of phosphatidylinositol 3'-kinase and is involved in interleukin 6-induced neuroendocrine differentiation of prostate ... in Proceedings of the National Academy of Sciences of the United States of America 1998 (PubMed)
    Show all 4 Pubmed References

  3. Human Monoclonal BMX Primary Antibody für ELISA, WB - ABIN968989 : Palmer, Mutch, Workman, McDaid, Horwood, Foxwell: Bmx tyrosine kinase regulates TLR4-induced IL-6 production in human macrophages independently of p38 MAPK and NFkapp}B activity. in Blood 2008 (PubMed)
    Show all 2 Pubmed References

  4. Human Polyclonal BMX Primary Antibody für IHC (p), ELISA - ABIN544376 : Pan, An, Zhang, He, Yin, Min: Etk/Bmx as a tumor necrosis factor receptor type 2-specific kinase: role in endothelial cell migration and angiogenesis. in Molecular and cellular biology 2002 (PubMed)
    Show all 3 Pubmed References

Weitere Antikörper gegen BMX Interaktionspartner

Human BMX Non-Receptor Tyrosine Kinase (BMX) Interaktionspartner

  1. tyrosine kinase BMX is negatively regulated by androgen and contributes to castration-resistant prostate cancer by enhancing the phosphorylation and activation of multiple receptor tyrosine kinases following androgen deprivation therapy

  2. Epithelial and endothelial tyrosine kinase (Etk) interacts with 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 (PFKFB4) to promote small-cell lung cancer (SCLC) chemoresistance through regulation of autophagy.

  3. results demonstrate that hypoxia-dependent upregulation of BMX contributes to therapeutic resistance through a compensatory prosurvival signaling mechanism. These results also reveal the role of off-target drug effects on tumor microenvironment and development of acquired drug resistance.

  4. These results suggested that BMX can promote cell proliferation through PI3K/AKT/mTOR and STAT3 signaling pathways in cervical cancer cells.

  5. The studies suggested that BMXDeltaN might play roles in lung tumorigenicity, with expression of BMXDeltaN promoting cell growth, cell migration, and cell transformation.

  6. results demonstrate that cleaved BMX is a novel N-end rule substrate, and its degradation exhibits a novel interplay between substrate phosphorylation and N-end rule degradation, revealing an increasing complex regulatory network of apoptotic proteolytic signaling cascades.

  7. Data indicate that EPHA3 is involved in regulating the multidrug resistance (MDR) of small cell lung cancer (SCLC) via PI3K/BMX/STAT3 signaling and may be a therapeutic target in SCLC.

  8. BMX directly inhibits a core component of the intrinsic apoptosis machinery opens opportunities to improve the efficacy of existing chemotherapy by potentiating BAK-driven cell death in cancer cells.

  9. Report BMX-ARHGAP gene fusion in gastric cardia adenocarcinoma.

  10. These findings suggested that polymorphisms of the BMX gene could be a potential predictor of clinical symptoms following mTBI.

  11. BMX is an antiapoptotic downstream effector of PI3K, independent of AKT.

  12. The effects of dietary K(+) on Bmx were more pronounced

  13. Overexpression of ETK is associated with the malignancy and disease progression of renal cell carcinoma.

  14. This review characterizes the role of BMX in inflamamtion, cardiovascular disease and cancer.

  15. Etk/BMX may play a role in protection of NPC cells from apoptosis.

  16. study concludes that BMX is an essential component of inflammatory cytokine signaling and that catalytic, as well as noncatalytic functions of BMX are involved

  17. Deregulation of ETK may attribute to the elevated activity of STAT3 and AKT frequently detected in bladder cancer.

  18. BMX is associated with multi-drug resistance of K562/HHT cell line.

  19. Constitutively active STAT3 rescued the effects of BMX downregulation, supporting that BMX signals through STAT3 in glioblastoma stem cells (GSCs).

  20. possible role in regulation of vesicle trafficking

Mouse (Murine) BMX Non-Receptor Tyrosine Kinase (BMX) Interaktionspartner

  1. results suggest that the endothelial Bmx tyrosine kinase could provide a target to attenuate the development of cardiac hypertrophy

  2. Btk, Tec, Bmx are required for TLR-dependent signaling in many types of myeloid cells while being tissue-specific.

  3. Tyrosine kinase BMX phosphorylates phosphotyrosine-primed motif mediating the activation of multiple receptor tyrosine kinases.

  4. Our findings therefore indicate that Bmx activity contributes to tumor angiogenesis and growth.

  5. genetic ablation of BMX conferred protection in arthritis model confirming BMX an essential mediator of inflammation in vivo; conclude BMX an essential component of inflammatory cytokine signaling and catalytic as well noncatalytic functions are involved

  6. Investigate Bmx mediates VEGF-dependent lymphangiogenic signaling.

  7. by preventing binding of Etk/Bmx to PAR(1) -C-tail, hPar1 oncogenic properties are abrogated

  8. activation of Etk largely co-localizes with TNFR2 in vascular endothelial cells and cardiomyocytes.

  9. Bmx overexpression accelerates keratinocyte proliferation and wound reepithelialization. Bmx expression also induces chronic inflammation and angiogenesis in the skin.

  10. Role of Bmx in ischemia-mediated arteriogenesis/angiogenesis: response to ischemia, reduced in knockout mice and enhanced in transgenic mice.

  11. BMX knockout mice are resistant to cardiac hypertrophy induced by transverse aortic constriction compared to wild-type mice.

BMX Antigen-Profil

Protein Überblick

This gene encodes a non-receptor tyrosine kinase belonging to the Tec kinase family. The protein contains a PH-like domain, which mediates membrane targeting by binding to phosphatidylinositol 3,4,5-triphosphate (PIP3), and a SH2 domain that binds to tyrosine-phosphorylated proteins and functions in signal transduction. The protein is implicated in several signal transduction pathways including the Stat pathway, and regulates differentiation and tumorigenicity of several types of cancer cells. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Genbezeichner und Symbole assoziert mit BMX

  • BMX non-receptor tyrosine kinase (BMX) Antikörper
  • BMX non-receptor tyrosine kinase (bmx) Antikörper
  • BMX non-receptor tyrosine kinase (Bmx) Antikörper
  • BMX Antikörper
  • Etk Antikörper
  • Etk/Bmx Antikörper
  • PSCTK2 Antikörper
  • PSCTK3 Antikörper
  • RGD1565643 Antikörper
  • Tyro8 Antikörper

Bezeichner auf Proteinebene für BMX

BMX non-receptor tyrosine kinase , cytoplasmic tyrosine-protein kinase BMX-like , BTK-like on X chromosome , Etk/Bmx cytosolic tyrosine kinase , NTK38 tyrosine kinase , bone marrow tyrosine kinase gene in chromosome X protein , cytoplasmic tyrosine-protein kinase BMX , epithelial and endothelial tyrosine kinase , TYRO8 protein tyrosine kinase 8 , bone marrow tyrosine kinase gene in chromosome X protein homolog

GENE ID SPEZIES
428003 Gallus gallus
712722 Macaca mulatta
100051025 Equus caballus
100408267 Callithrix jacchus
100432500 Pongo abelii
100565102 Anolis carolinensis
100602159 Nomascus leucogenys
660 Homo sapiens
12169 Mus musculus
367786 Rattus norvegicus
491750 Canis lupus familiaris
100516528 Sus scrofa
531514 Bos taurus
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