anti-BMX Non-Receptor Tyrosine Kinase (BMX) Antikörper

Human BMX Non-Receptor Tyrosine Kinase (BMX) Interaktionspartner

1. results demonstrate that cleaved BMX is a novel N-end rule substrate, and its degradation exhibits a novel interplay between substrate phosphorylation and N-end rule degradation, revealing an increasing complex regulatory network of apoptotic proteolytic signaling cascades.

2. Data indicate that EPHA3 (zeige EPHA3 Antikörper) is involved in regulating the multidrug resistance (MDR) of small cell lung cancer (SCLC) via PI3K (zeige PIK3CA Antikörper)/BMX/STAT3 (zeige STAT3 Antikörper) signaling and may be a therapeutic target in SCLC.

3. BMX directly inhibits a core component of the intrinsic apoptosis machinery opens opportunities to improve the efficacy of existing chemotherapy by potentiating BAK (zeige BAK1 Antikörper)-driven cell death in cancer cells.

4. Report BMX-ARHGAP gene fusion in gastric cardia adenocarcinoma.

5. These findings suggested that polymorphisms of the BMX gene could be a potential predictor of clinical symptoms following mTBI.

6. BMX is an antiapoptotic downstream effector of PI3K (zeige PIK3CA Antikörper), independent of AKT (zeige AKT1 Antikörper).

7. The effects of dietary K(+) on Bmx were more pronounced

8. Overexpression of ETK is associated with the malignancy and disease progression of renal cell carcinoma (zeige MOK Antikörper).

9. This review characterizes the role of BMX in inflamamtion, cardiovascular disease and cancer.

10. Etk/BMX may play a role in protection of NPC (zeige NPC1 Antikörper) cells from apoptosis.

Mouse (Murine) BMX Non-Receptor Tyrosine Kinase (BMX) Interaktionspartner

1. results suggest that the endothelial Bmx tyrosine kinase (zeige TYRO3 Antikörper) could provide a target to attenuate the development of cardiac hypertrophy

2. Btk (zeige BTK Antikörper), Tec (zeige NR4A3 Antikörper), Bmx are required for TLR-dependent signaling in many types of myeloid cells while being tissue-specific.

3. Tyrosine kinase (zeige TYRO3 Antikörper) BMX phosphorylates phosphotyrosine-primed motif mediating the activation of multiple receptor tyrosine kinases.

4. Our findings therefore indicate that Bmx activity contributes to tumor angiogenesis and growth.

5. genetic ablation of BMX conferred protection in arthritis model confirming BMX an essential mediator of inflammation in vivo; conclude BMX an essential component of inflammatory cytokine signaling and catalytic as well noncatalytic functions are involved

6. Investigate Bmx mediates VEGF (zeige VEGFA Antikörper)-dependent lymphangiogenic signaling.

7. by preventing binding of Etk/Bmx to PAR(1 (zeige MARK2 Antikörper)) -C-tail, hPar1 oncogenic properties are abrogated

8. activation of Etk largely co-localizes with TNFR2 (zeige TNFRSF1B Antikörper) in vascular endothelial cells and cardiomyocytes.

9. Bmx overexpression accelerates keratinocyte proliferation and wound reepithelialization. Bmx expression also induces chronic inflammation and angiogenesis in the skin.

10. Role of Bmx in ischemia-mediated arteriogenesis/angiogenesis: response to ischemia, reduced in knockout mice and enhanced in transgenic mice.