anti-24-Dehydrocholesterol Reductase (DHCR24) Antikörper

DHCR24 encodes a flavin adenine dinucleotide (FAD)-dependent oxidoreductase which catalyzes the reduction of the delta-24 double bond of sterol intermediates during cholesterol biosynthesis.

Alle Antikörper anzeigen Gen GeneID UniProt
Anti-Human DHCR24 DHCR24 1718 Q15392
Anti-Maus DHCR24 DHCR24 74754 Q8VCH6
Anti-Ratte DHCR24 DHCR24 298298  
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Top anti-Seladin 1 Antikörper auf antikoerper-online.de

Showing 10 out of 61 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB WB Suggested Anti-DHCR24 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:62500  Positive Control:  721_B cell lysate DHCR24 is supported by BioGPS gene expression data to be expressed in 721_B Host:  Rabbit  Target Name:  DHCR24  Sample Type:  Human Fetal Heart  Antibody Dilution:  1.0ug/ml 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Rind (Kuh) Kaninchen Unkonjugiert IHC, WB WB Suggested Anti-DHCR24 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:312500  Positive Control:  THP-1 cell lysate Rabbit Anti-DHCR24 Antibody   Formalin Fixed Paraffin Embedded Tissue: Human heart Tissue Observed Staining: Cytoplasmic Primary Antibody Concentration: 1:100 Other Working Concentrations: 1:600 Secondary Antibody: Donkey anti-Rabbit-Cy3 Secondary Antibody Concentration: 1:200 Magnification: 20X Exposure Time: 0.5 - 2.0 sec 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Kaninchen Unkonjugiert ICC, IF, IHC (p), WB IHC-P Image Immunohistochemical analysis of paraffin-embedded SW480 xenograft, using Seladin 1, antibody at 1:100 dilution. ICC/IF Image Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using Seladin 1, antibody at 1:200 dilution. 100 μL Anmelden zum Anzeigen 1 bis 2 Tage
$358.60
Details
Human Kaninchen Unkonjugiert WB Western blot analysis of anti-DHCR24 Antibody (Center)(ABIN389353) in HepG2 cell line lysates (35 µg/lane). DHCR24 (arrow) was detected using the purified polyclonal antibody. 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Human Kaninchen Unkonjugiert WB Western blot analysis of anti-DHCR24 Antibody (N-term) (ABIN389352) in HepG2 cell line lysates (35 µg/lane). DHCR24 (arrow) was detected using the purified polyclonal antibody. Western blot analysis of anti-DHCR24 Antibody (N-term) (ABIN389352) in mouse liver tissue lysates (35 µg/lane). DHCR24 (arrow) was detected using the purified polyclonal antibody. 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Human Kaninchen Unkonjugiert ICC, IF, IHC (p), IHC, WB Western Blot: Seladin 1 Antibody [NBP1-32247] - Sample (30 ug of whole cell lysate) A: A431 7. 5% SDS PAGE Seladin 1 antibody, antibody diluted at 1:1000. Immunohistochemistry-Paraffin: Seladin 1 Antibody [NBP1-32247] - Paraffin-embedded SW480 xenograft, using antibody at 1:100 dilution. 0.1 mL Anmelden zum Anzeigen 7 bis 9 Tage
$514.63
Details
Human Kaninchen Unkonjugiert EIA, WB 0.4 mL Anmelden zum Anzeigen 6 bis 8 Tage
$390.50
Details
Human Kaninchen Unkonjugiert EIA, WB 0.4 mL Anmelden zum Anzeigen 6 bis 8 Tage
$390.50
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Rind (Kuh) Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$551.83
Details
Fledermaus Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$551.83
Details

Am meisten referenzierte anti-Seladin 1 Antikörper

  1. Human Polyclonal Seladin 1 Primary Antibody für WB - ABIN514969 : Gilk, Cockrell, Luterbach, Hansen, Knodler, Ibarra, Steele-Mortimer, Heinzen: Bacterial colonization of host cells in the absence of cholesterol. in PLoS pathogens 2013 (PubMed)

Weitere Antikörper gegen Seladin 1 Interaktionspartner

Human 24-Dehydrocholesterol Reductase (DHCR24) Interaktionspartner

  1. the expanding database of post-translational modifications will be a valuable resource for mapping the topology of membrane-associated proteins, such as DHCR24, that is, flagging cytosolic residues accessible to modifying enzymes such as kinases and ubiquitin ligases.

  2. DHCR24 auto-antibody represents a potential noninvasive biomarker for hepatitis C virus-related liver disease and may facilitate the diagnosis of PIVKA-II and AFP (zeige AFP Antikörper)-negative hepatocellular carcinoma.

  3. physical and functional interaction between DHCR24 and DHCR7 (zeige DHCR7 Antikörper)

  4. In vitro experiments showed that DHCR24 overexpression induced tumor proliferation.

  5. Data (including data from studies using RNA from post-mortem brain tissue) suggest that expression of DHCR24 is up-regulated in parietal cortex of patients with Huntington's disease as compared to control subjects.

  6. Data indicate a mechanism whereby 3beta-hydroxysterol Delta24-reductase (DHCR24) activity is regulated by signaling.

  7. DHCR24 expression protects neuronal cells from apoptotic cell death induced by endoplasmic reticulum stress.

  8. TR-beta (zeige TXNRD2 Antikörper) and LXR-alpha (zeige NR1H3 Antikörper) competitively up-regulate the human Seladin-1 promoter, sharing the same response element, site A.

  9. DHCR24 gene expression is regulation by cholesterol availability.

  10. a novel role for 24,25EC in cholesterol homeostasis, through its rapid inhibition of cholesterol synthesis at DHCR24.

Mouse (Murine) 24-Dehydrocholesterol Reductase (DHCR24) Interaktionspartner

  1. When DHCR24 is genetically deleted there is a decreased association of EAAT2 (zeige SLC1A2 Antikörper) with lipid rafts after ischemia.

  2. Data (including data from transgenic mice) suggest that expression of Dhcr24 is down-regulated in brain tissues of mice exhibiting symptoms modeling advanced Huntington's disease.

  3. RE1-silencing transcription factor (zeige REST Antikörper) acts because it is bound in close proximity to SREBP, thus amplifying its ability to upregulate 24-dehydrocholesterol reductase

  4. concluded that TH up-regulates Seladin-1 gene expression at the transcriptional level and LXR-alpha (zeige NR1H3 Antikörper) maintains the gene expression

  5. This is the first demonstration that DHCR24 plays an important role in long bone growth by protecting chondrocytes from reactive oxygen species.

  6. Seladin-1 is shown to be an LPS (zeige TLR4 Antikörper)-responsive gene that negatively regulates the TNF- alpha (zeige TNF Antikörper) production and bone resorption in response to LPS (zeige TLR4 Antikörper).

  7. Seladin-1-dependent cholesterol synthesis is involved in lowering Abeta (zeige APP Antikörper) levels.

  8. cellular cholesterol biosynthesis is critical for the activation and maintenance of the Akt (zeige AKT1 Antikörper)-Bad cell survival cascade in response to growth factors such as insulin (zeige INS Antikörper).

  9. Cholesterol homeostasis in Dhcr24 knockout mice is characterized by strong activation of liver X receptor-targeted genes and by mechanisms compensating for cholesterol depletion.

  10. ablation of DHCR24/seladin-1 prevented apoptosis of primary neurons in a p53 (zeige TP53 Antikörper)-dependent manner

Seladin 1 (DHCR24) Antigen-Profil

Protein Überblick

This gene encodes a flavin adenine dinucleotide (FAD)-dependent oxidoreductase which catalyzes the reduction of the delta-24 double bond of sterol intermediates during cholesterol biosynthesis. The protein contains a leader sequence that directs it to the endoplasmic reticulum membrane. Missense mutations in this gene have been associated with desmosterolosis. Also, reduced expression of the gene occurs in the temporal cortex of Alzheimer disease patients and overexpression has been observed in adrenal gland cancer cells.

Genbezeichner und Symbole assoziert mit DHCR24

  • 24-dehydrocholesterol reductase (DHCR24) Antikörper
  • 24-dehydrocholesterol reductase S homeolog (dhcr24.S) Antikörper
  • 24-dehydrocholesterol reductase (dhcr24) Antikörper
  • delta(24)-sterol reductase (LOC5575872) Antikörper
  • 24-dehydrocholesterol reductase (CpipJ_CPIJ000670) Antikörper
  • 24-dehydrocholesterol reductase (Dhcr24) Antikörper
  • 2310076D10Rik Antikörper
  • 5830417J06Rik Antikörper
  • DCE Antikörper
  • MGC82737 Antikörper
  • mKIAA0018 Antikörper
  • Nbla03646 Antikörper
  • seladin-1 Antikörper
  • SELADIN1 Antikörper
  • zgc:101638 Antikörper

Bezeichner auf Proteinebene für DHCR24

24-dehydrocholesterol reductase , 3 beta-hydroxysterol delta 24-reductase , 3-beta-hydroxysterol delta-24-reductase , delta(24)-sterol reductase , desmosterol-to-cholesterol enzyme , diminuto/dwarf1 homolog , seladin 1 , selective AD indicator 1 , 3-beta-hydroxysterol delta-24 reductase , seladin-1

GENE ID SPEZIES
424661 Gallus gallus
447786 Xenopus laevis
456879 Pan troglodytes
489573 Canis lupus familiaris
494102 Danio rerio
549554 Xenopus (Silurana) tropicalis
5575872 Aedes aegypti
6031429 Culex quinquefasciatus
100546716 Meleagris gallopavo
100584832 Nomascus leucogenys
1718 Homo sapiens
74754 Mus musculus
298298 Rattus norvegicus
533726 Bos taurus
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