anti-Human TLE4 Antikörper für Immunofluorescence (Paraffin-embedded Sections)

Recommended TLE4 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Transducin-Like Enhancer of Split 4 (E(sp1) Homolog, Drosophila) (TLE4) Antikörper
  • TLE4
  • NV17443
  • BCE-1
  • BCE1
  • E(spI)
  • ESG
  • ESG4
  • GRG4
  • Esp2
  • Grg4
  • XGrg-4
  • XTCF-4
  • Xgrg4
  • Xtle4
  • esg4
  • grg4
  • gro
  • 5730411M05Rik
  • AA792082
  • Bce-1
  • Bce1
  • ESTM13
  • ESTM14
  • X83332
  • X83333
  • transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
  • transducin-like enhancer of split 4 (E(sp1) homolog)
  • transducin-like enhancer of split 4, homolog of Drosophila E(spl)
  • TLE4
  • LOC100229224
  • Tle4
  • tle4
Reaktivität
Human, Maus, Ratte (Rattus)
81
40
39
6
3
2
2
2
2
2
1
1
1
1
Wirt
Kaninchen
64
17
Klonalität
Polyklonal
Konjugat
Dieser TLE4 Antikörper ist konjugiert mit Cy3
3
3
3
2
2
2
1
1
1
1
1
1
1
1
1
1
Applikation
Immunofluorescence (Paraffin-embedded Sections) (IF (p))
66
34
13
12
11
5
2
2
Optionen
Hersteller
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Produktnummer ABIN1703197
414,64 €
Zzgl. Versandkosten 20,00 € und MWSt
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
1 ABIN1705008 IF (p) Cy5 Rabbit IgG Anmelden zum Anzeigen Polyclonal
1 ABIN1706966 IF (p) Cy5.5 Rabbit IgG Anmelden zum Anzeigen Polyclonal
1 ABIN1708777 IF (p) Cy7 Rabbit IgG Anmelden zum Anzeigen Polyclonal
1 ABIN1710588 IF (p) FITC Rabbit IgG Anmelden zum Anzeigen Polyclonal
1 ABIN1694117 IF (p) Alexa Fluor 350 Rabbit IgG Anmelden zum Anzeigen Polyclonal
1 ABIN1695943 IF (p) Alexa Fluor 488 Rabbit IgG Anmelden zum Anzeigen Polyclonal
1 ABIN1697760 IF (p) Alexa Fluor 555 Rabbit IgG Anmelden zum Anzeigen Polyclonal
1 ABIN2807055 IF (p) Alexa Fluor 594 Rabbit IgG Anmelden zum Anzeigen Polyclonal
1 ABIN1699571 IF (p) Alexa Fluor 647 Rabbit IgG Anmelden zum Anzeigen Polyclonal
1 ABIN1714887 IF (p) IHC (p) WB Rabbit IgG Anmelden zum Anzeigen Polyclonal
1 ABIN5011649 IF (p) Alexa Fluor 680 Rabbit IgG Anmelden zum Anzeigen Polyclonal
1 ABIN5011650 IF (p) Alexa Fluor 750 Rabbit IgG Anmelden zum Anzeigen Polyclonal

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Applikation / Reaktivität Human Maus Ratte (Rattus)
Western Blotting (WB) 66 Antikörper 28 Antikörper 27 Antikörper
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 11 Antikörper 10 Antikörper 10 Antikörper
Immunohistochemistry (IHC) 13 Antikörper 12 Antikörper 11 Antikörper
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 13 Antikörper 13 Antikörper 13 Antikörper
Immunofluorescence (IF) 5 Antikörper
Immunocytochemistry (ICC) 2 Antikörper
Enzyme Immunoassay (EIA) 2 Antikörper 1 Antikörper 1 Antikörper
ELISA 34 Antikörper

General

Antigen Transducin-Like Enhancer of Split 4 (E(sp1) Homolog, Drosophila) (TLE4) Antikörper
Reaktivität Human, Maus, Ratte (Rattus)
(81), (40), (39), (6), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1)
Wirt Kaninchen
(64), (17)
Klonalität
Polyklonal
Konjugat Dieser TLE4 Antikörper ist konjugiert mit Cy3
(3), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Applikation Immunofluorescence (Paraffin-embedded Sections) (IF (p))
(66), (34), (13), (12), (11), (5), (2), (2)
Hersteller Anmelden zum Anzeigen

Produktdetails anti-TLE4 Antikörper

Target Details TLE4 Anwendungsinformationen Handhabung Bilder
Reinigung Purified by Protein A.
Immunogen KLH conjugated synthetic peptide derived from human TLE4
Isotyp IgG

Target Details TLE4

Produktdetails anti-TLE4 Antikörper Anwendungsinformationen Handhabung Bilder zurück nach oben
Antigen
Andere Bezeichnung Tle4 (TLE4 Antibody Abstract)
Hintergrund

The Notch signaling pathway controls cellular interactions important for the specification of a variety of fates in both invertebrates and vertebrates. Key players in the Notch pathway are the TLE genes (for transducin-like enhancer of split, also designated ESG for enhancer of split groucho), which are human homologs of the Drosophila groucho gene. Groucho is a transcriptional repressor that plays a key role in neurogenesis, segmentation and sex determination. TLEs associate with chromatin in live cells and specifically with Histone H3, but not with other core histones. Expression of the TLE genes, TLE1, TLE2, TLE3 and TLE4, correlate with immature epithelial cells that are progressing toward a terminally differentiated state, suggesting a role during epithelial differentiation. TLE1, TLE2 and TLE3 have elevated expression in cervical squamous metaplasias and carcinomas, while TLE4 is most highly expressed in the brain, particularly in the caudate nucleus. TLE1 and TLE4 contain SP and WD40 domains, through which TLE1 binds AML1 to inhibit AML1-induced transactivation of the CSF1 receptor. In early stages of cell differentiation, TLE1 is upregulated, and TLE2 and TLE4 are downregulated. In later stages, TLE2 and TLE4 are upregulated, and expression of TLE1 decreases.

Synonyms: B lymphocyte gene 1, B lymphocyte gene 1, enhancer of split groucho 4, enhancer of split groucho 4, ESG4, ESG4, KIAA1261, TIM, TIM1, timeless Drosophila homolog, TLE4, transducin-like enhancer of split 4, transducin-like enhancer of split 4, TLE4_HUMAN.

Gen-ID 7091
Forschungsgebiet Chromatin and Nuclear Signaling, Transcription Factors, Wnt
Pathways WNT Signalweg

Anwendungsinformationen

Produktdetails anti-TLE4 Antikörper Target Details TLE4 Handhabung Bilder zurück nach oben
Applikationshinweise IF(IHC-P) 1:50-200
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-TLE4 Antikörper Target Details TLE4 Anwendungsinformationen Bilder zurück nach oben
Format Liquid
Konzentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Lagerung 4 °C
Informationen zur Lagerung Store at 4°C
Haltbarkeit 12 months