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results suggest that nucleoporin 50 plays an essential role in the survival of primordial germ cells during embryonic development
Results suggest a transport-independent role for Nup50 in chromatin biology that occurs away from the NPC (zeige NPC1 ELISA Kits).
findings show that the Nup50 N-terminal domain actively displaces NLSs from importin-alpha, which would be more consistent with Nup50 functioning to coordinate import complex disassembly and importin recycling
Interacts with the melanocortin 2 receptor (zeige MC2R ELISA Kits), participating in its translocation to the nucleus.
analysis of the Nup153 (zeige NUP153 ELISA Kits)-Nup50 protein interface and its role in nuclear import
Nucleoporin Nup50 stabilizes closed conformation of armadillo repeat 10 in importin alpha5.
Results suggest that Npap60L and Npap60S function differently in nuclear protein (zeige RDBP ELISA Kits) import.
The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins are the main components of the nuclear pore complex in eukaryotic cells. The protein encoded by this gene is a member of the FG-repeat containing nucleoporins that functions as a soluble cofactor in importin-alpha:beta-mediated nuclear protein import. Pseudogenes of this gene are found on chromosomes 5, 6, and 14. Two transcript variants encoding different isoforms have been found for this gene.
nuclear pore complex protein Nup50
, nucleoporin 50kDa
, nucleoporin 50 kDa
, nuclear pore complex protein Nup50-like
, 50 kDa nucleoporin
, Nucleoprotein 50kD
, nucleoporin Nup50
, nucleoprotein 50
, nuclear pore associated protein 60 kDa
, nuclear pore-associated protein 60L