anti-MAP4K1 (MAP4K1) Antikörper

Bezeichnung:
anti-Mitogen-Activated Protein Kinase Kinase Kinase Kinase 1 Antikörper (MAP4K1)
Auf www.antikoerper-online.de finden Sie aktuell 133 Mitogen-Activated Protein Kinase Kinase Kinase Kinase 1 (MAP4K1) Antikörper von 18 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen MAP4K1 Proteine (6) und und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 147 MAP4K1 Produkte verfügbar.
Synonyme:
Hpk1, mHPK1
Alle Antikörper anzeigen Gen GeneID UniProt
MAP4K1 292763  
MAP4K1 11184 Q92918
MAP4K1 26411 P70218

Alle Spezies anzeigen

Weitere Synonyme anzeigen

Meistgesuchte Reaktivitäten zu anti-MAP4K1 (MAP4K1) Antikörper

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anti-Rat (Rattus) MAP4K1 Antikörper:

anti-Human MAP4K1 Antikörper:

anti-Mouse (Murine) MAP4K1 Antikörper:

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Am meisten referenzierte anti-MAP4K1 Antikörper

  1. Human Polyclonal MAP4K1 Primary Antibody für EIA - ABIN358386 : Hu, Qiu, Wang, Meyer, Tan: Human HPK1, a novel human hematopoietic progenitor kinase that activates the JNK/SAPK kinase cascade. in Genes & development 1996 (PubMed)
    Zeige alle 3 Referenzen für 358386

  2. Human Polyclonal MAP4K1 Primary Antibody für EIA - ABIN358384 : Beausoleil, Jedrychowski, Schwartz, Elias, Villén, Li, Cohn, Cantley, Gygi: Large-scale characterization of HeLa cell nuclear phosphoproteins. in Proceedings of the National Academy of Sciences of the United States of America 2004 (PubMed)
    Zeige alle 3 Referenzen für 358384

  3. Human Polyclonal MAP4K1 Primary Antibody für IHC (p), WB - ABIN392502 : Sawasdikosol, Russo, Burakoff: Hematopoietic progenitor kinase 1 (HPK1) negatively regulates prostaglandin E2-induced fos gene transcription. in Blood 2003 (PubMed)
    Zeige alle 2 Referenzen für 392502

  4. Cow (Bovine) Polyclonal MAP4K1 Primary Antibody für WB - ABIN2773872 : Brenner, Golks, Becker, Müller, Frey, Novak, Melamed, Kiefer, Krammer, Arnold: Caspase-cleaved HPK1 induces CD95L-independent activation-induced cell death in T and B lymphocytes. in Blood 2007 (PubMed)

Weitere Antikörper gegen MAP4K1 Interaktionspartner

Human Mitogen-Activated Protein Kinase Kinase Kinase Kinase 1 (MAP4K1) Interaktionspartner

  1. CUL7 (zeige CUL7 Antikörper)/Fbxw8 (zeige FBXW8 Antikörper) ubiquitin ligase-mediated HPK1 degradation revealed a direct link and novel role of CUL7 (zeige CUL7 Antikörper)/Fbxw8 (zeige FBXW8 Antikörper) ubiquitin ligase in the MAPK (zeige MAPK1 Antikörper) pathway, which plays a critical role in cell proliferation and differentiation.

  2. HPK1 is critically involved in LFA-1 (zeige ITGAL Antikörper)-mediated polymorphonuclear neutrophils trafficking during acute inflammation.

  3. results indicate that uncleaved HPK1 is a positive regulator of vitamin D-induced differentiation in acute myeloid leukemia (zeige BCL11A Antikörper) cells, but the cleaved HPK1 fragment inhibits differentiation

  4. Pdcd4 (zeige PDCD4 Antikörper) knockdown up-regulates MAP kinase (zeige MAPK1 Antikörper) kinase kinase kinase 1 (MAP4K1) expression and increases phosphorylation of c-Jun (zeige JUN Antikörper).

  5. QVD and 1,25D-induced differentiation was accompanied by increased signaling by Hematopoietic Progenitor Kinase 1(HPK1), and the expression of transcription factors known to be involved in monocytic differentiation was increased.

  6. HPK1 negatively regulates T cell activation by reducing the persistence of signaling microclusters.

  7. The purpose of the study was to investigate the potential contribution of HPK1, MEKK1 (zeige MAP3K1 Antikörper), TAK1 (zeige MAP3K7 Antikörper), p-MKK4 (zeige MAP2K4 Antikörper) to the development of extramammary Paget disease

  8. The catalytic activity of a hematopoietic cell-restricted, Ste20-related S/TPK, HPK1, is positively regulated by exposure to physiological concentrations of PGE2. HPK1 is a negative regulator of PGE2-induced FOS gene transcription.

  9. PP4 (zeige ANXA5 Antikörper) is a positive regulator for HPK1 and the HPK1-JNK (zeige MAPK8 Antikörper) signaling pathway

  10. Full activation of HPK1 is dependent on autophosphorylation of threonine 165 and phosphorylation of serine 171, which is a target site for protein kinase D (PKD) in vitro.

Mouse (Murine) Mitogen-Activated Protein Kinase Kinase Kinase Kinase 1 (MAP4K1) Interaktionspartner

  1. Introduction of three 4-R-hydroxyproline residues stabilizes the SH3m-cortactin (zeige CTTN Antikörper) binding of HPK1 peptide.

  2. a novel negative feedback regulation of BCR (zeige BCR Antikörper) signaling by HPK1-mediated phosphorylation, ubiquitination, and subsequent degradation of the activated BLNK (zeige BLNK Antikörper)

  3. HPK1 associates with SKAP1 (zeige SKAP1 Antikörper) to negatively regulate Rap1 (zeige TERF2IP Antikörper)-mediated B-lymphocyte (zeige AKAP17A Antikörper) adhesion.

  4. HPK1 competes with ADAP for SLP-76 binding and via Rap1 negatively affects T-cell adhesion.

  5. Hpk1 supports apoptosis of T lymphocytes by inhibiting the antiapoptotic action of NF-kappaB (zeige NFKB1 Antikörper) and inducing the proapoptotic activity of JNK (zeige MAPK8 Antikörper).

  6. Mona/Gads (zeige GRAP2 Antikörper) SH3C binding to hematopoietic progenitor kinase 1 (HPK1) combines an atypical SH3 binding motif, R/KXXK, with a classical PXXP motif embedded in a polyproline type II (PPII) helix

  7. suppression or activation of NFkappaB by HPK1 determines sensitivity to activation-induced cell death

  8. HPK1-C as a suppressor of antiapoptotic Bcl-2 (zeige BCL2 Antikörper) proteins and provide a molecular basis for our understanding of CD95L (zeige FASL Antikörper)-independent activation-induced cell death of lymphocytes.

  9. Our data reveal a novel role for HPK1 as a negative regulator of dendritic cell functions

MAP4K1 Antigen-Profil

Beschreibung des Gens

May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway. May play a role in hematopoietic lineage decisions and growth regulation.

Alternative names and synonyms associated with MAP4K1

  • mitogen activated protein kinase kinase kinase kinase 1 (Map4k1) Antikörper
  • mitogen-activated protein kinase kinase kinase kinase 1 (MAP4K1) Antikörper
  • mitogen-activated protein kinase kinase kinase kinase 1 (Map4k1) Antikörper
  • Hpk1 Antikörper
  • mHPK1 Antikörper

Bezeichner auf Proteinebene für MAP4K1

mitogen-activated protein kinase kinase kinase kinase 1 , MAPK/ERK kinase kinase kinase 1 , MEK kinase kinase 1 , MEKKK 1 , hematopoietic progenitor kinase 1 , HPK , mitogen activated protein kinase kinase kinase kinase 1

GENE ID SPEZIES
292763 Rattus norvegicus
522002 Bos taurus
11184 Homo sapiens
26411 Mus musculus
484527 Canis lupus familiaris
100516374 Sus scrofa
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