Inositol Polyphosphate-5-Phosphatase, 145kDa (INPP5D) ELISA Kits

Bezeichnung:
Inositol Polyphosphate-5-Phosphatase, 145kDa ELISA Kits (INPP5D)
Auf www.antikoerper-online.de finden Sie aktuell 16 Inositol Polyphosphate-5-Phosphatase, 145kDa (INPP5D) ELISA Kits von 10 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen Inositol Polyphosphate-5-Phosphatase, 145kDa Antikörper (146) und Inositol Polyphosphate-5-Phosphatase, 145kDa Proteine (3) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 174 Inositol Polyphosphate-5-Phosphatase, 145kDa Produkte verfügbar.
Synonyme:
13.t00027, 256.t00004, AI323613, hp51CN, INPP5D, s-SHIP, SHIP, SHIP-1, SHIP1, SIP-145

Inositol Polyphosphate-5-Phosphatase, 145kDa (INPP5D) ELISA Kits nach Reaktivitäten

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Weitere ELISA Kits für Inositol Polyphosphate-5-Phosphatase, 145kDa Interaktionspartner

Zebrafish Inositol Polyphosphate-5-Phosphatase, 145kDa (INPP5D) Interaktionspartner

Mouse (Murine) Inositol Polyphosphate-5-Phosphatase, 145kDa (INPP5D) Interaktionspartner

  1. Rictor (zeige RICTOR ELISA Kits) positively regulates B cell receptor signaling via up-regulating Btk (zeige BTK ELISA Kits) and down-regulating SH2-containing inositol phosphatase

  2. MiR (zeige MLXIP ELISA Kits)-155 promotes experimental colitis by repressing SHIP-1 expression.

  3. Results are consistent with predicted/observed reduction in the Lyn-SHIP-1-PTEN-SHP-1 axis function in B cells from systemic lupus

  4. SHIP has a role in extracellular matrix accumulation via suppressing PI3K/Akt (zeige AKT1 ELISA Kits)/CTGF (zeige CTGF ELISA Kits) signaling in diabetic kidney dise

  5. this study shows that FcgammaRIIb drives the sequential dephosphorylation system comprising SHIP1/2 and Inpp4a (zeige INPP4A ELISA Kits), and accelerates phagosome acidification

  6. Data (including data from studies in knockout mice) suggest that up-regulation of signaling in colonic mucosa via interleukin-10 (zeige IL10 ELISA Kits)/microRNA-155/SHIP-1 (Src homology 2 domain-containing inositol-5-phosphatase) is involved in development of colitis due to dysbiosis.

  7. Our results describe a critical role for SHIP-1 in regulating the ability of dendritic cells to efficiently prime Th2-type responses.

  8. Findings indicate a role for inositol-polyphosphate 5-phosphatase SHIP-1 coupling to DC-type lectin receptor ectin-1 hemITAM in the selective control of downstream responses.

  9. miR (zeige MLXIP ELISA Kits)-155 regulates the delicate balance between PAK1 (zeige PAK1 ELISA Kits)-mediated proliferation and apoptosis in T cells impacting lymphoid organ size and function.

  10. miR (zeige MLXIP ELISA Kits)-155 regulation of SHIP represents a unique axis that regulates dendritic cells function in vivo.

Human Inositol Polyphosphate-5-Phosphatase, 145kDa (INPP5D) Interaktionspartner

  1. JARID1B directly bound to PI3K (zeige PIK3CA ELISA Kits)/AKT (zeige AKT1 ELISA Kits) signaling inhibitor SHIP1 gene promoter and decreased SHIP1 gene expression.

  2. Study shows that SHIP1 activity is decreased in adult Crohn's disease (CD) patients either through reduced intrinsic enxymatic activity or reduced protein expression, and propose that in addition to ATG16L1 (zeige ATG16L1 ELISA Kits), SHIP1 may contribute to the risk conferred by the 2q37 CD risk locus.

  3. results indicate that FcgammaRIIB is not uniquely able to promote membrane recruitment of SHIP, but rather modulates its function via formation of distinct signaling complexes. Membrane recruitment of SHIP via Syk (zeige SYK ELISA Kits)-dependent mechanisms may be an important factor modulating immunoreceptor signaling.

  4. SHIP has a role in extracellular matrix accumulation via suppressing PI3K (zeige PIK3CA ELISA Kits)/Akt (zeige AKT1 ELISA Kits)/CTGF (zeige CTGF ELISA Kits) signaling in diabetic kidney dise

  5. SHIP levels and activity are lower in intestinal tissues and peripheral blood samples from patients with Crohn's disease, resulting in induction of Il1-beta (zeige IL1B ELISA Kits).

  6. Underexpression of SHIP1 is associated with drug resistance in acute myeloid leukemia (zeige BCL11A ELISA Kits).

  7. ectopically expressed SHIP1 accumulates in nucleolar cavities and colocalizes with the tumor suppressor protein p53 (zeige TP53 ELISA Kits).

  8. Results show that expression of SHIP1 protein is targeted by miR (zeige MLXIP ELISA Kits)-155 in acute myeloid leukemia (zeige BCL11A ELISA Kits) (AML (zeige RUNX1 ELISA Kits)) suggesting it as an onco-miR (zeige MLXIP ELISA Kits). The miR (zeige MLXIP ELISA Kits)-155/SHIP1/PI3K (zeige PIK3CA ELISA Kits)/AKT (zeige AKT1 ELISA Kits) signaling pathway could play an important role in the pathogenesis of AML (zeige RUNX1 ELISA Kits).

  9. Overexpression of miR (zeige MLXIP ELISA Kits)-155 in the gouty synovial fluid mononuclear cells leads to suppress SHIP-1 levels and enhance proinflammatory cytokines.

  10. SLAMF7 (zeige SLAMF7 ELISA Kits)-triggered inhibition is mediated by a mechanism involving Src (zeige SRC ELISA Kits) kinases, CD45 (zeige PTPRC ELISA Kits), and SHIP-1 that is defective in MM cells

Inositol Polyphosphate-5-Phosphatase, 145kDa (INPP5D) Antigen-Profil

Beschreibung des Gens

This gene is a member of the inositol polyphosphate-5-phosphatase (INPP5) family and encodes a protein with an N-terminal SH2 domain, an inositol phosphatase domain, and two C-terminal protein interaction domains. Expression of this protein is restricted to hematopoietic cells where its movement from the cytosol to the plasma membrane is mediated by tyrosine phosphorylation. At the plasma membrane, the protein hydrolyzes the 5' phosphate from phosphatidylinositol (3,4,5)-trisphosphate and inositol-1,3,4,5-tetrakisphosphate, thereby affecting multiple signaling pathways. Overall, the protein functions as a negative regulator of myeliod cell proliferation and survival. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Alternative names and synonyms associated with Inositol Polyphosphate-5-Phosphatase, 145kDa (INPP5D)

  • inositol polyphosphate-5-phosphatase, 145kDa (INPP5D) Elisa Kit
  • inositol polyphosphate-5-phosphatase, 145kDa (inpp5d) Elisa Kit
  • inositol polyphosphate 5-phosphatase (EHI_159880) Elisa Kit
  • inositol polyphosphate 5-phosphatase (EHI_153490) Elisa Kit
  • phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 1 (inpp5d) Elisa Kit
  • Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 1 (ship1) Elisa Kit
  • inositol polyphosphate-5-phosphatase D (Inpp5d) Elisa Kit
  • 13.t00027 Elisa Kit
  • 256.t00004 Elisa Kit
  • AI323613 Elisa Kit
  • hp51CN Elisa Kit
  • INPP5D Elisa Kit
  • s-SHIP Elisa Kit
  • SHIP Elisa Kit
  • SHIP-1 Elisa Kit
  • SHIP1 Elisa Kit
  • SIP-145 Elisa Kit

Bezeichner auf Proteinebene für INPP5D

inositol polyphosphate-5-phosphatase, 145kDa , SH2 containing inositol phosphatase , phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 1 , phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 1-like , SH2 domain-containing inositol 5'-phosphatase 1 , SH2 domain-containing inositol phosphatase 1 , SH2 domain-containing inositol-5'-phosphatase 1 , SHIP-1 , phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 , Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 1 , SH2 containing inositol phosphotase , SH2-containing inositol phosphatase SHIP , SIP-145 , Src homology 2 domain-containing inositol-5-phosphatase , inositol polyphosphate-5-phosphatase of 145 kDa , inositol polyphosphate-5-phosphatase, 145 kDa , p150Ship , Inositol polyphosphate-5-phosphatase 145 kDa , Inositol polyphosphate-5-phosphatase, 145 kDa , signaling inositol polyphosphate 5 phosphatase SIP-145

GENE ID SPEZIES
424745 Gallus gallus
470683 Pan troglodytes
507329 Bos taurus
100021361 Monodelphis domestica
100400043 Callithrix jacchus
100446045 Pongo abelii
100464150 Ailuropoda melanoleuca
559103 Danio rerio
3404260 Entamoeba histolytica HM-1:IMSS
3410671 Entamoeba histolytica HM-1:IMSS
100064896 Equus caballus
100526019 Sus scrofa
100561031 Anolis carolinensis
399051 Xenopus laevis
100380693 Salmo salar
16331 Mus musculus
54259 Rattus norvegicus
3635 Homo sapiens
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