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anti-Human CHRM3 Antikörper:
anti-Rat (Rattus) CHRM3 Antikörper:
anti-Mouse (Murine) CHRM3 Antikörper:
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Mouse (Murine) Polyclonal CHRM3 Primary Antibody für IF (p), IHC (p) - ABIN674484
Chen, Li, Zhang, Zhai, Gong, Qiang, Xue: An ENU-induced mutation of Nrg1 causes dilated pupils and a reduction in muscarinic receptors in the sphincter pupillae. in PLoS ONE 2011
Show all 3 Pubmed References
Human Polyclonal CHRM3 Primary Antibody für ELISA, WB - ABIN560365
Cheng, Cao, Zheng, Wang, Sun, Liu, Zhang, Wang, Zhu, Wu: Airway hyperresponsiveness induced by repeated esophageal infusion of HCl in guinea pigs. in American journal of respiratory cell and molecular biology 2014
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Human Polyclonal CHRM3 Primary Antibody für IHC (p) - ABIN4336799
Stoffel, Monnard, Steiner, Mevissen, Meylan: Distribution of muscarinic receptor subtypes and interstitial cells of Cajal in the gastrointestinal tract of healthy dairy cows. in American journal of veterinary research 2006
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Human Polyclonal CHRM3 Primary Antibody für IHC, IHC (p) - ABIN4336801
Molina, Rodriguez-Diaz, Fachado, Jacques-Silva, Berggren, Caicedo: Control of insulin secretion by cholinergic signaling in the human pancreatic islet. in Diabetes 2014
Human Polyclonal CHRM3 Primary Antibody für IHC, ELISA - ABIN1584245
Moscovice: The future of rural hospitals. in Minnesota medicine 1989
Human Polyclonal CHRM3 Primary Antibody für IHC (p) - ABIN2475761
Billington, Penn: m3 muscarinic acetylcholine receptor regulation in the airway. in American journal of respiratory cell and molecular biology 2002
this study shows that anti-M3R (zeige CHRM4 Antikörper) is significantly elevated in Sjogren's syndrome plasma in comparison with rheumatoid arthritis, systemic lupus erythematosus, and healthy controls
Interacting post-muscarinic receptor (zeige CHRM5 Antikörper) signaling pathways potentiate MMP1 (zeige MMP1 Antikörper) expression and invasion of human colon cancer cells.
M3R (zeige CHRM4 Antikörper) expression plays an important role in early progression and invasion of colon neoplasia but is less important once tumors have spread.
This study presents the endocytic pathways of internalization for muscarinic type 3 receptor and flotillin-1 (zeige FLOT1 Antikörper)/2 in salivary gland epithelial cells. knockdown of flot-1 (zeige FLOT1 Antikörper) or -2 by flotillin (zeige FLOT2 Antikörper)-specific siRNA prevented internalization and reduced the endocytic efficiency of muscarinic type 3 receptor.
M3-mAChR activation leads to enhancement of hsp expression via PKC (zeige PRRT2 Antikörper)-dependent phosphorylation of HSF1 (zeige HSF1 Antikörper), thereby stabilizing the mutant hERG (zeige KCNH2 Antikörper)-FLAG protein. Thus, M3-mAChR activators may have a therapeutic value for patients with LQT2 (zeige KCNH2 Antikörper).
There were no significant associations between CHRM3 SNPs and autonomic nervous system activity in patients with schizophrenia on high-dose antipsychotics.
To our knowledge, this is the first genetic association study that reveals the genetic contribution of CHRM3 gene in bladder cancer etiology.
The CHRM3 gene plays a role in abnormal thalamo-orbital frontal cortex functional connectivity in first-episode treatment-naive patients with schizophrenia.
These findings indicate that M3 mAChR may be important therapeutic target for obstructive airway diseases, as it regulates the effects of the epithelial-derived chemokines on ASM (zeige SMPD1 Antikörper) cell migration, which results in lung remodeling.
Blockading CHRM3 by shRNA or treatment with darifenacin inhibited prostate cancer growth.
Data suggest that both M(2) and M(3) muscarinic receptors mediate the contraction in both pig clasp (zeige CLASRP Antikörper) and sling fibers similar to human clasp (zeige CLASRP Antikörper) and sling fibers.
Sequential activation of muscarinic M3 receptors and cannabinoid CB1 (zeige CNR1 Antikörper) receptors produce synergistic contractile effects of the bovine ciliary muscle by involving the activation of Rho-kinase (zeige ROCK1 Antikörper) and protein kinase C (zeige PKC Antikörper).
These data support the existence of a novel transducing cascade, involving Galpha (zeige SUCLG1 Antikörper)(q16)beta gamma coupling M(3)AChR to NPR (zeige NPTXR Antikörper)-GC.
airway M(2)Rs inhibit BK channels by a dual, Gbetagamma-mediated mechanism, a direct membrane-delimited interaction, and the activation of the phospholipase C (zeige PLC Antikörper)/protein kinase C (zeige PKC Antikörper) pathway
Stimulation of the ERK (zeige EPHB2 Antikörper) pathway in Gnb5 (zeige GNB5 Antikörper)(-/-) cells by epidermal growth factor (zeige EGF Antikörper) restored M3R-stimulated insulin (zeige INS Antikörper) release to near normal levels. Identification of the novel role of Gbeta5 (zeige GNB5 Antikörper)-R7 in insulin (zeige INS Antikörper) secretion may lead to a new therapeutic approach for improving pancreatic beta-cell function
s. Moreover, we found that M3 cholinergic receptor (CHRM3) was upregulated in a large subset of benign prostatic hyperplasia (BPH (zeige GLI3 Antikörper)) tissues compared with normal tissues. Activation of CHRM3 also promoted the proliferation of BPH (zeige GLI3 Antikörper) cells.
early intervention with cholinergic receptor muscarinic (ChRM)-3 blocker reversed the progression of airway hyperreactivity in the neonatal exposure model, whereas beta2-adrenoceptor agonists had no such effect
Arthritis-induced joint destruction was significantly stronger in mice with M3 muscarinic acetylcholine receptor deficiency.
The effects of muscarinic receptor (zeige CHRM5 Antikörper) M3 knockout on cathepsin K (zeige CTSK Antikörper) expression, bone density and biomechanical properties of bone are reported.
results suggest that the autoantibodies against peptides of the second extracellular loop of M3R are not pathogenic in vivo and they are not suitable as biomarkers for pSS (zeige CDSN Antikörper) diagnosis
Expression of the M3 receptors mediating cholinergic contractile stimuli of the detrusor muscle was dysregulated in both Mras (zeige MRAS Antikörper)-/- males and females, although only males exhibited a urinary phenotype.
The study screened CrkL (zeige CRKL Antikörper) binding proteins using RNA interference (RNAi) and identified Sorbs1 (zeige SORBS1 Antikörper) and Sorbs2 (zeige Sorbs2 Antikörper) as two proteins that are enriched at AChR clusters and are required for the formation of AChR aggregation in vitro.
Activation of Chrm3 inhibits the recruitment of beta-arrestin-2 (zeige ARRB2 Antikörper) to odorant receptors, resulting in a potentiation of odor-induced responses in olfactory sensory neurons.
The muscarinic M3R receptor interacts directly with NOSTRIN (zeige NOSTRIN Antikörper) at the plasma membrane in the aorta.
G-protein coupled receptor, muscarinic receeptor subtype that mediates cholinergic-induced contraction in most smooth muscle
m3 muscarinic acetylcholine receptor
, muscarinic acetylcholine receptor M3
, cholinergic receptor, muscarinic 3
, acetylcholine receptor, muscarinic 3
, m3 muscarinic receptor
, cholinergic receptor, muscarinic 3, cardiac
, M3 muscarinic acetylcholine receptor
, AChR M3
, mm3 mAChR
, muscarinic acetylcholine receptor 3