anti-Unc-13 Homolog A (C. Elegans) (UNC13A) Antikörper

Bezeichnung:
anti-Unc-13 Homolog A (C. Elegans) Antikörper (UNC13A)
Auf www.antikoerper-online.de finden Sie aktuell 11 Unc-13 Homolog A (C. Elegans) (UNC13A) Antikörper von 7 unterschiedlichen Herstellern. Insgesamt sind aktuell 11 Unc-13 Homolog A (C. Elegans) Produkte verfügbar.
Synonyme:
2410078G03Rik, Munc13-1, Munc13-2, Unc13a, Unc13h1, Unc13h2

Meistgesuchte Reaktivitäten zu anti-Unc-13 Homolog A (C. Elegans) (UNC13A) Antikörper

Wählen Sie die Spezies und Applikation aus

anti-Human Antikörper:

anti-Mouse (Murine) Antikörper:

anti-Rat (Rattus) Antikörper:

Alle verfügbaren anti-Unc-13 Homolog A (C. Elegans) Antikörper

Sie gelangen zu unserer vorgefilterten Suche.

Am meisten referenzierte anti-Unc-13 Homolog A (C. Elegans) Antikörper

  1. Mouse (Murine) Monoclonal UNC13A Primary Antibody für IP, ELISA - ABIN1742276 : Martín, Durroux, Ciruela, Torres, Pin, Sánchez-Prieto: The metabotropic glutamate receptor mGlu7 activates phospholipase C, translocates munc-13-1 protein, and potentiates glutamate release at cerebrocortical nerve terminals. in The Journal of biological chemistry 2010 (PubMed)
    Zeige alle 6 Referenzen für 1742276

  2. Human Polyclonal UNC13A Primary Antibody für ICC, IP - ABIN1742277 : Rinetti, Schweizer: Ubiquitination acutely regulates presynaptic neurotransmitter release in mammalian neurons. in The Journal of neuroscience : the official journal of the Society for Neuroscience 2010 (PubMed)
    Zeige alle 3 Referenzen für 1742277

Weitere Antikörper gegen Unc-13 Homolog A (C. Elegans) Interaktionspartner

Human Unc-13 Homolog A (C. Elegans) (UNC13A) Interaktionspartner

  1. Synaptic UNC13A protein variant causes increased neurotransmission and dyskinetic movement disorder

  2. UNC13A rs12608932 is a risk factor for ALS and a modifying factor for survival and disease progression rate in a Spanish cohort.

  3. Munc13-1, on account of its role in both insulin (zeige INS Antikörper) and neurotransmitter exocytosis and through its binding properties, may be an important factor contributing to the development or progression of diabetic neuropathy.

  4. UNC13A provides a novel link between amyotrophic lateral sclerosis and frontotemporal dementia and identifies changes in neurotransmitter release and synaptic function as a converging mechanism in the pathogenesis of ALS (zeige IGFALS Antikörper) and FTD (zeige FTL Antikörper)-TDP.

  5. CAPS1 (zeige CAPS Antikörper) binds to the full-length of cytoplasmic syntaxin-1 (zeige STX1A Antikörper) with preference to its "open" conformation, whereas Munc13-1 binds to the first 80 N-terminal residues of syntaxin-1 (zeige STX1A Antikörper).

  6. This study demonistrated that UNC13A influences survival in Italian amyotrophic lateral sclerosis patients.

  7. Our results further corroborate the role of UNC13A in amyotrophic lateral sclerosis pathogenesis.

  8. Here, we report that, like Rab3A (zeige RAB3A Antikörper), RIM (zeige RBBP8 Antikörper) and Munc13 (zeige UNC13B Antikörper) are present in human sperm and that they play a functional role in acrosomal exocytosis before the acrosomal calcium efflux

  9. Results do not provide evidence of an association between a variant in the UNC13A gene and susceptibility to sporadic Amyotrophic lateral sclerosis in a French homogeneous population.

  10. rs12608932 Single Nucleotide Polymorphism is located at 19p13.3 and maps to a haplotype block within the boundaries of UNC13A, which regulates the release of neurotransmitters such as glutamate (zeige GRIN1 Antikörper) at neuromuscular synapses.

Mouse (Murine) Unc-13 Homolog A (C. Elegans) (UNC13A) Interaktionspartner

  1. Synaptic UNC13A protein variant causes increased neurotransmission and dyskinetic movement disorder

  2. SIGNIFICANCE STATEMENT: DBA (zeige RPS19 Antikörper)/2J and C57BL/6J mice have been used to understand the genetic mechanisms controlling behaviors related to a number of psychiatric illnesses. However, the fundamental neurobiological mechanisms producing these behavioral characteristics remain unresolved. Here we identify a critical family of presynaptic proteins differentially expressed by these strains that control strain-dependent synaptic ph

  3. Munc13-2 (zeige UNC13B Antikörper) is recruited to synapses by the AZ protein ELKS1.

  4. Munc13-2 (zeige UNC13B Antikörper) plays a fundamental role in large dense-core vesicle exocytosis, but in contrast to synapses lacking Munc13s, the corresponding chromaffin cells do not exhibit a vesicle docking defect.

  5. Data demonstrate that Munc13-1 and DOC2B (zeige DOC2B Antikörper) have different effects on network activity and that by enhancing asynchronous release, DOC2B (zeige DOC2B Antikörper) exerts its properties to increase spiking activity and elevate synchronization between neurons within network bursts

  6. Munc13-1 isoform is functionaly redundant in cytotoxic T lymphocytes.

  7. betaARs couple to a cAMP/Epac (zeige RAPGEF3 Antikörper)/PLC (zeige HSPG2 Antikörper)/Munc13-1/Rab3a (zeige RAB3A Antikörper)/RIM1a (zeige RIMS1 Antikörper)-dependent pathway to enhance glutamate (zeige GRIN1 Antikörper) release at cerebrocortical nerve terminals.

  8. CAPS1 (zeige CAPS Antikörper) binds to the full-length of cytoplasmic syntaxin-1 (zeige STX1A Antikörper) with preference to its "open" conformation, whereas Munc13-1 binds to the first 80 N-terminal residues of syntaxin-1 (zeige STX1A Antikörper).

  9. Our data establish Munc13-1 as a major presynaptic target of Ca(2 (zeige CA2 Antikörper)+)-Calmodulin signaling and show that the Ca(2 (zeige CA2 Antikörper)+)-Calmodulin-Munc13-1 complex is a pivotal component of the molecular machinery that determines short-term synaptic plasticity characteristics.

  10. The Munc13 (zeige UNC13B Antikörper) gene family encodes molecules located at the synaptic active zone that regulate the reliability of synapses to encode information over a wide range of frequencies in response to action potentials.

Unc-13 Homolog A (C. Elegans) (UNC13A) Antigen-Profil

Beschreibung des Gens

This gene encodes a member of the UNC13 family. UNC13 proteins bind to phorbol esters and diacylglycerol and play important roles in neurotransmitter release at synapses. Single nucleotide polymorphisms in this gene may be associated with sporadic amyotrophic lateral sclerosis.

Alternative names and synonyms associated with Unc-13 Homolog A (C. Elegans) (UNC13A)

  • unc-13 homolog A (C. elegans) (UNC13A) Antikörper
  • unc-13 homolog A (C. elegans) (Unc13a) Antikörper
  • unc-13 homolog B (C. elegans) (Unc13b) Antikörper
  • 2410078G03Rik Antikörper
  • Munc13-1 Antikörper
  • Munc13-2 Antikörper
  • Unc13a Antikörper
  • Unc13h1 Antikörper
  • Unc13h2 Antikörper

Bezeichner auf Proteinebene für UNC13A

protein unc-13 homolog A , UNC-13 homolog 1 , munc13 , protein unc-13 homolog B , unc-13 homolog A , unc13 homolog 1

GENE ID SPEZIES
23025 Homo sapiens
382018 Mus musculus
64829 Rattus norvegicus
22249 Mus musculus
Ausgewählte Anbieter für anti-Unc-13 Homolog A (C. Elegans) (UNC13A) Antikörper
Haben Sie etwas anderes gesucht?