anti-Maus SCO1 Cytochrome C Oxidase Assembly Protein Antikörper für Enzyme Immunoassay

Recommended SCO1 Cytochrome C Oxidase Assembly Protein Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
SCO1 Cytochrome C Oxidase Assembly Protein (SCO1) Antikörper
  • Bs
  • CD117
  • Fdc
  • Gsfsco1
  • Gsfsco5
  • Gsfsow3
  • SCO1
  • SCO5
  • SOW3
  • Ssm
  • Tr-kit
  • W
  • c-KIT
  • SCOD1
  • RGD1559538
  • kit oncogene
  • SCO cytochrome oxidase deficient homolog 1 (yeast)
  • SCO1 cytochrome c oxidase assembly protein
  • Kit
  • SCO1
  • Sco1
Epitop
Center
5
3
3
2
2
2
1
1
1
Reaktivität
Human, Maus, Ratte (Rattus)
32
14
14
4
3
3
3
3
2
1
1
Wirt
Kaninchen
28
4
Klonalität
Polyklonal
Applikation
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
29
13
10
8
7
3
Hersteller
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Hersteller Produkt- Nr.
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Produktnummer ABIN5555209
$ 375.38
Zzgl. Versandkosten $45.00

General

Antigen SCO1 Cytochrome C Oxidase Assembly Protein (SCO1) Antikörper
Epitop Center
(5), (3), (3), (2), (2), (2), (1), (1), (1)
Reaktivität Human, Maus, Ratte (Rattus)
(32), (14), (14), (4), (3), (3), (3), (3), (2), (1), (1)
Wirt Kaninchen
(28), (4)
Klonalität
Polyklonal
Applikation Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(29), (13), (10), (8), (7), (3)
Hersteller Anmelden zum Anzeigen

Produktdetails

Antigendetails Anwendungsinformationen Handhabung Bilder
Spezifität This antibody detects SCO1 / SCOD1 (both isoforms). It has no cross-reactivity to SCO2.
Kreuzreaktivität (Details) Species reactivity (tested):Human, mouse, rat
Reinigung Peptide affinity chromatography
Immunogen SCO1 antibody was raised against a 14 amino acid peptide from near the center of human SCO1.
Isotyp IgG

Antigendetails

Produktdetails Anwendungsinformationen Handhabung Bilder zurück nach oben
Antigen
Andere Bezeichnung SCO1 / SCOD1 (SCO1 Antibody Abstract)
Hintergrund Synthesis of cytochrome c oxidase 1 was initially identified in yeast as one of two cytochrome c oxidase (COX) assembly proteins that enable the assembly of cytochrome c holoenzyme, a complex that catalyzes the transfer of reducing equivalents from cytochrome c to molecular oxygen and pumps protons across the inner mitochondrial membrane. Like their yeast homologs, the function of both SCO1 and SCO2 are dependent on copper ion binding. Mutations in either gene can lead to cytochrome c oxidase respiratory chain defects, with a missense mutation in human SCO1 (P174L) associated with a fatal neonatal hepatopathy when the second allele is also non-functional, suggesting the pathology is due to loss of function. It has been suggested that this mutation alters the SCO1 affinity for the copper (I) ion, thus impairing the efficiency of copper transfer to the cytochrome c oxidase. At least two isoforms of SCO1 are known to exist.Synonyms: Protein SCO1 homolog mitochondrial
Gen-ID 6341
UniProt O75880
Pathways Sensory Perception of Sound, Transition Metal Ion Homeostasis, Stem Cell Maintenance, Production of Molecular Mediator of Immune Response, Regulation of long-term Neuronal Synaptic Plasticity

Anwendungsinformationen

Produktdetails Antigendetails Handhabung Bilder zurück nach oben
Applikationshinweise ELISA. Western blot: 0.5 - 1 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails Antigendetails Anwendungsinformationen Bilder zurück nach oben
Buffer PBS containing 0.02 % sodium azide
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freezing and thawing.
Lagerung 4 °C/-20 °C
Informationen zur Lagerung Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.