anti-Human E-cadherin Antikörper für Immunohistochemistry

Recommended E-cadherin Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Cadherin 1, Type 1, E-Cadherin (Epithelial) (CDH1) Antikörper
  • Arc-1
  • CD324
  • CDHE
  • ECAD
  • LCAM
  • UVO
  • E-cadherin
  • cdh1
  • si:dz180o5.2
  • dZ71B9.1
  • si:dz180o5.1
  • uvo
  • lcam
  • E-Cad
  • XBcad
  • l-cam
  • xcdh1
  • cdhc-A
  • xb-cad
  • XTCAD-1
  • c-cadherin
  • cadherin-1
  • uvomorulin
  • XB-cadherin
  • CDH1
  • CDH16
  • HPT-1
  • HPT1
  • arc-1
  • cd324
  • cdhe
  • ecad
  • cad17
  • hpt1
  • cdh16
  • hpt-1
  • LI-cadherin
  • cadherin-17
  • b-cadherin
  • cdh1-a
  • cdhp
  • hjmd
  • pcad
  • AA960649
  • E-cad
  • Ecad
  • L-CAM
  • Um
  • Arc1
  • cadherin 1, type 1, E-cadherin (epithelial)
  • si:busm1-180o5.2
  • cadherin 1, epithelial
  • cadherin 1
  • si:busm1-180o5.1
  • cadherin 17, LI cadherin (liver-intestine)
  • Cadherin-17
  • cadherin 3, type 1, P-cadherin (placental)
  • E-cadherin-like
  • Aerobic running capacity QTL 1
  • CDH1
  • si:busm1-180o5.2
  • cdh1
  • Cdh1
  • si:busm1-180o5.1
  • CDH17
  • cad17
  • cdh17
  • cdh3-a
  • LOC100356548
  • Arunc1
Epitop
Middle Region
98
35
35
31
28
19
16
15
15
14
13
10
6
6
6
5
5
4
4
4
4
4
4
4
4
4
4
4
4
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
Reaktivität
Rind (Kuh), Hund, Pferd, Human, Maus, Schwein, Kaninchen, Ratte (Rattus), Zebrafisch
833
256
145
40
25
15
8
7
7
6
5
4
3
1
1
1
1
1
1
1
1
1
Wirt
Kaninchen
567
273
51
25
2
Klonalität
Polyklonal
Konjugat
Dieser E-cadherin Antikörper ist unkonjugiert
43
40
38
27
24
21
19
19
17
16
15
13
13
13
13
12
12
11
10
10
9
9
6
4
4
3
3
3
3
3
3
2
Applikation
Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting (WB)
650
399
285
214
193
174
164
90
88
38
23
14
13
12
10
7
6
6
4
4
2
2
2
2
1
1
1
Optionen
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Bilder

Produktnummer ABIN2784498
$ 289.00
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
9.508871 ABIN4899264 CyTOF FACS ICC IHC WB Mouse IgG2b AA 155-707 Anmelden zum Anzeigen 180224 4
9.508871 ABIN4899267 CyTOF FACS ICC IHC SimWes WB Goat IgG AA 157-709 Anmelden zum Anzeigen Polyclonal 14
9.508871 ABIN2704739 IC FACS IF IP IHC WB Rabbit C-Term Anmelden zum Anzeigen Polyclonal
9.508871 ABIN967801 IF IP IHC WB Mouse IgG2a, kappa C-Term Anmelden zum Anzeigen 36-E 5
9.508871 ABIN1533229 IF IHC ELISA WB Rabbit IgG AA 1-50 Anmelden zum Anzeigen Polyclonal
9.508871 ABIN969036 FACS IHC ELISA WB Mouse IgG1 Anmelden zum Anzeigen 7H12 3
9.508871 ABIN2707486 IHC WB Rabbit N-Term Anmelden zum Anzeigen Polyclonal
9.508871 ABIN1871697 IHC IP WB Rabbit IgG Anmelden zum Anzeigen Polyclonal
9.508871 ABIN3181505 IHC WB Rabbit IgG Anmelden zum Anzeigen Polyclonal
9.508871 ABIN258859 IHC (p) IHC WB Mouse IgG2 Anmelden zum Anzeigen MM0039-21E9
9.508871 ABIN4306607 IHC WB Mouse IgG2a Anmelden zum Anzeigen CL1180
9.508871 ABIN4306606 IHC WB Mouse IgG1 Anmelden zum Anzeigen CL1172
9.508871 ABIN4306605 IHC WB Mouse IgG2b Anmelden zum Anzeigen CL1170
9.508871 ABIN266226 IHC (p) IHC Rabbit Anmelden zum Anzeigen Polyclonal
9.508871 ABIN2852544 IHC WB Rabbit Anmelden zum Anzeigen Polyclonal
9.508871 ABIN2470944 IHC ELISA WB Mouse IgG1 kappa AA 381-481 Anmelden zum Anzeigen 3F4
9.508871 ABIN266227 IHC (p) IHC Rabbit Anmelden zum Anzeigen Polyclonal
9.508871 ABIN3030242 IHC ELISA WB Mouse IgG1, kappa Anmelden zum Anzeigen 813CT11-1-3
9.508871 ABIN933086 IF IHC ELISA WB Mouse IgG1 Anmelden zum Anzeigen 7H12
9.508871 ABIN2405772 IHC WB Rabbit IgG Anmelden zum Anzeigen Polyclonal

General

Antigen Cadherin 1, Type 1, E-Cadherin (Epithelial) (CDH1) Antikörper
Epitop Middle Region
(98), (35), (35), (31), (28), (19), (16), (15), (15), (14), (13), (10), (6), (6), (6), (5), (5), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reaktivität Rind (Kuh), Hund, Pferd, Human, Maus, Schwein, Kaninchen, Ratte (Rattus), Zebrafisch
(833), (256), (145), (40), (25), (15), (8), (7), (7), (6), (5), (4), (3), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Wirt Kaninchen
(567), (273), (51), (25), (2)
Klonalität
Polyklonal
Konjugat Dieser E-cadherin Antikörper ist unkonjugiert
(43), (40), (38), (27), (24), (21), (19), (19), (17), (16), (15), (13), (13), (13), (13), (12), (12), (11), (10), (10), (9), (9), (6), (4), (4), (3), (3), (3), (3), (3), (3), (2)
Applikation Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting (WB)
(650), (399), (285), (214), (193), (174), (164), (90), (88), (38), (23), (14), (13), (12), (10), (7), (6), (6), (4), (4), (2), (2), (2), (2), (1), (1), (1)
Pubmed 1 Publikation vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-E-cadherin Antikörper

Target Details E-cadherin Anwendungsinformationen Handhabung Referenzen für anti-E-cadherin Antikörper (ABIN2784498) Bilder
Blocking Peptide Zu diesem Produkt passt das Blocking Peptide ABIN974746.
Sequenz QEITSYTAQE PDTFMEQKIT YRIWRDTANW LEINPDTGAI STRAELDRED
Homologie Cow: 93%, Dog: 79%, Horse: 93%, Human: 100%, Mouse: 79%, Pig: 93%, Rabbit: 93%, Rat: 93%, Zebrafish: 85%
Produktmerkmale This is a rabbit polyclonal antibody against CDH1. It was validated on Western Blot using a cell lysate as a positive control.
Reinigung Affinity Purified
Immunogen The immunogen is a synthetic peptide directed towards the middle region of human CDH1

Target Details E-cadherin

Produktdetails anti-E-cadherin Antikörper Anwendungsinformationen Handhabung Referenzen für anti-E-cadherin Antikörper (ABIN2784498) Bilder zurück nach oben
Antigen
Andere Bezeichnung CDH1 (CDH1 Antibody Abstract)
Hintergrund Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells, cadherins may thus contribute to the sorting of heterogeneous cell types. CDH1 is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells. Has a potent invasive suppressor role. It is a ligand for integrin alpha-E/beta-7.This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function is thought to contribute to progression in cancer by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. Identified transcript variants arise from mutation at consensus splice sites. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: Arc-1, CD324, CDHE, ECAD, LCAM, UVO
Protein Interaction Partner: UBC, MDM2, UCHL3, CDC27, PTEN, CTNNB1, PIP5K1C, CTNND1, CBLL1, RNF2, GMNN, LMNA, KRT18, KRT9, KRT8, KRT1, IGHA1, HSPD1, HSP90AA1, HSPA9, HSPA8, HSPA5, GBAS, CTNNA1, CRYAB, CFTR, C1QBP, ACTN4, ACADVL, ANP32B, NIPSNAP1, XRCC5, TGM2, SKP2, SET, RAD17, POLR2E
Protein Size: 882
Molekulargewicht 80 kDa
Gen-ID 999
NCBI Accession NM_004360, NP_004351
UniProt P12830
Forschungsgebiet Proteolysis / Ubiquitin
Pathways Sensory Perception of Sound, Cell-Cell Junction Organization, Tube Formation

Anwendungsinformationen

Produktdetails anti-E-cadherin Antikörper Target Details E-cadherin Handhabung Referenzen für anti-E-cadherin Antikörper (ABIN2784498) Bilder zurück nach oben
Applikationshinweise Optimal working dilutions should be determined experimentally by the investigator.
Kommentare

Antigen size: 882 AA

Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-E-cadherin Antikörper Target Details E-cadherin Anwendungsinformationen Referenzen für anti-E-cadherin Antikörper (ABIN2784498) Bilder zurück nach oben
Format Liquid
Konzentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freeze-thaw cycles.
Lagerung -20 °C
Informationen zur Lagerung For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-E-cadherin Antikörper (ABIN2784498)

Produktdetails anti-E-cadherin Antikörper Target Details E-cadherin Anwendungsinformationen Handhabung Bilder zurück nach oben
Allgemeine Veröffentlichungen

Onder, Gupta, Mani, Yang, Lander, Weinberg: "Loss of E-cadherin promotes metastasis via multiple downstream transcriptional pathways." in: Cancer research, Vol. 68, Issue 10, pp. 3645-54, 2008

Bilder

Produktdetails anti-E-cadherin Antikörper Target Details E-cadherin Anwendungsinformationen Handhabung Referenzen für anti-E-cadherin Antikörper (ABIN2784498) zurück nach oben
Bilder des Herstellers
Western Blotting (WB) image for anti-Cadherin 1, Type 1, E-Cadherin (Epithelial) (CDH1) (Middle Region) antibody (ABIN2784498) WB Suggested Anti-CDH1 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: ...
Immunohistochemistry (IHC) image for anti-Cadherin 1, Type 1, E-Cadherin (Epithelial) (CDH1) (Middle Region) antibody (ABIN2784498) anti-Cadherin 1, Type 1, E-Cadherin (Epithelial) (CDH1) (Middle Region) antibody (Image 2)
Immunohistochemistry (IHC) image for anti-Cadherin 1, Type 1, E-Cadherin (Epithelial) (CDH1) (Middle Region) antibody (ABIN2784498) anti-Cadherin 1, Type 1, E-Cadherin (Epithelial) (CDH1) (Middle Region) antibody (Image 3)
Immunofluorescence (IF) image for anti-Cadherin 1, Type 1, E-Cadherin (Epithelial) (CDH1) (Middle Region) antibody (ABIN2784498) Sample Type: Rat FRTL-5 cells

Primary Antibody Dilution: 1:100