anti-Ratte (Rattus) COL2A1 Antikörper für Immunohistochemistry (Frozen Sections)

Recommended COL2A1 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Collagen, Type II, alpha 1 (COL2A1) Antikörper
  • COL2A1
  • Col2
  • Col2a
  • Col2a-1
  • Del1
  • Dmm
  • Lpk
  • M100856
  • Rgsc856
  • ANFH
  • AOM
  • COL11A3
  • SEDC
  • CG2A1A
  • COLLII
  • CB11
  • col2a1a
  • collagen, type II, alpha 1
  • type II Collagen
  • col2a1
  • col2a1b
  • COL2A1
  • Col2a1
  • LOC100009005
Epitop
AA 1222-1241, C-Term
16
15
13
10
4
4
3
2
2
2
2
1
1
1
1
Reaktivität
Maus, Ratte (Rattus)
55
34
30
8
4
3
3
2
2
Wirt
Kaninchen
66
7
1
1
Klonalität
Polyklonal
Konjugat
Dieser COL2A1 Antikörper ist unkonjugiert
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Applikation
Immunohistochemistry (Frozen Sections) (IHC (fro)), Western Blotting (WB)
48
24
21
17
17
16
15
13
9
7
6
5
1
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Produktnummer ABIN5518709
$ 200.00
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
1 ABIN567566 IHC (fro) IHC (p) WB Mouse IgG1 Chain alpha 1 Anmelden zum Anzeigen II-4C11 7
1 ABIN116553 EIA IHC (fro) WB Biotin Rabbit Chain alpha 1 Anmelden zum Anzeigen Polyclonal
1 ABIN1450180 EIA IHC (fro) IHC (p) IP WB Rabbit Chain alpha 1 Anmelden zum Anzeigen Polyclonal
1 ABIN116552 EIA IHC (fro) IHC (p) IP WB Rabbit Chain alpha 1 Anmelden zum Anzeigen Polyclonal
1 ABIN113096 EIA IHC (fro) IF Rabbit Chain alpha 1 Anmelden zum Anzeigen Polyclonal
1 ABIN2487215 EIA IHC (fro) IF IHC (p) RIA Rabbit Chain alpha 1 Anmelden zum Anzeigen Polyclonal
1 ABIN3028574 IHC (fro) WB Rabbit IgG C-Term Anmelden zum Anzeigen Polyclonal

General

Antigen Collagen, Type II, alpha 1 (COL2A1) Antikörper
Epitop AA 1222-1241, C-Term
(16), (15), (13), (10), (4), (4), (3), (2), (2), (2), (2), (1), (1), (1), (1)
Reaktivität Maus, Ratte (Rattus)
(55), (34), (30), (8), (4), (3), (3), (2), (2)
Wirt Kaninchen
(66), (7), (1), (1)
Klonalität
Polyklonal
Konjugat Dieser COL2A1 Antikörper ist unkonjugiert
(2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Applikation Immunohistochemistry (Frozen Sections) (IHC (fro)), Western Blotting (WB)
(48), (24), (21), (17), (17), (16), (15), (13), (9), (7), (6), (5), (1)
Pubmed 17 Publikationen vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-COL2A1 Antikörper

Target Details COL2A1 Anwendungsinformationen Handhabung Referenzen für anti-COL2A1 Antikörper (ABIN5518709) Bilder
Verwendungszweck Rabbit IgG polyclonal antibody for Collagen alpha-1(II) chain(COL2A1) detection. Tested with WB, IHC-F in Mouse,Rat.
Sequenz AFAGLGQREK GPDPMQYMRA
Kreuzreaktivität (Details) No cross reactivity with other proteins.
Produktmerkmale Rabbit IgG polyclonal antibody for Collagen alpha-1(II) chain(COL2A1) detection. Tested with WB, IHC-F in Mouse,Rat.
Gene Name: collagen, type II, alpha 1
Protein Name: Collagen alpha-1(II) chain
Reinigung Immunogen affinity purified.
Immunogen A synthetic peptide corresponding to a sequence at the C-terminus of mouse Collagen II1222-1241aa AFAGLGQREKGPDPMQYMRA), different from the related rat sequence by one amino acid.
Isotyp IgG

Target Details COL2A1

Produktdetails anti-COL2A1 Antikörper Anwendungsinformationen Handhabung Referenzen für anti-COL2A1 Antikörper (ABIN5518709) Bilder zurück nach oben
Antigen
Andere Bezeichnung COL2A1 (COL2A1 Antibody Abstract)
Hintergrund Collagen, type II, alpha 1, also known as COL2A1, is a human gene which is the major collagen synthesized by chondrocvtes. COL2A1 is mapped to 12q13.11. This gene encodes the alpha-1 chain of type II collagen, a fibrillar collagen found in cartilage and the vitreous humor of the eye. Mutations in this gene are associated with achondrogenesis, chondrodysplasia, early onset familial osteoarthritis, SED congenita, Langer-Saldino achondrogenesis, Kniest dysplasia, Stickler syndrome type I, and spondyloepimetaphyseal dysplasia Strudwick type. In addition, defects in processing chondrocalcin, a calcium binding protein that is the C-propeptide of this collagen molecule, are also associated with chondrodysplasia.

Synonyms: Alpha 1 type II collagen antibody|Alpha-1 type II collagen antibody|AOM antibody|Cartilage collagen antibody|Chondrocalcin antibody|CO2A1_HUMAN antibody|COL11A3 antibody|COL2A1 antibody|COL2A1 protein antibody|Collagen alpha 1(II) chain precursor antibody|Collagen II alpha 1 polypeptide antibody|Collagen type II alpha 1(primary osteoarthritis spondyloepiphyseal dysplasia congenital) antibody|MGC131516 antibody|SEDC antibody
UniProt P28481
Pathways Sensory Perception of Sound, Growth Factor Binding

Anwendungsinformationen

Produktdetails anti-COL2A1 Antikörper Target Details COL2A1 Handhabung Referenzen für anti-COL2A1 Antikörper (ABIN5518709) Bilder zurück nach oben
Applikationshinweise WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Rat, Predicted Species: Mouse, The detection limit for COL2A1 is approximately 1 ng/lane under reducing conditions.
IHC-F: Concentration: 0.5-1 μg/mL, Tested Species: Rat, Predicted Species: Mouse
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.
Kommentare

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(F).

Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-COL2A1 Antikörper Target Details COL2A1 Anwendungsinformationen Referenzen für anti-COL2A1 Antikörper (ABIN5518709) Bilder zurück nach oben
Format Lyophilized
Rekonstitution Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
Konzentration 500 μg/mL
Buffer Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
Konservierungsmittel Sodium azide, Thimerosal (Merthiolate)
Vorsichtsmaßnahmen This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
Lagerung 4 °C,-20 °C
Informationen zur Lagerung At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Referenzen für anti-COL2A1 Antikörper (ABIN5518709)

Produktdetails anti-COL2A1 Antikörper Target Details COL2A1 Anwendungsinformationen Handhabung Bilder zurück nach oben
Produkt verwendet in:

Liu, Lu, Wu, Zheng: "Chondroprotective effects of taurine in primary cultures of human articular chondrocytes." in: The Tohoku journal of experimental medicine, Vol. 235, Issue 3, pp. 201-13, 2015

Ye, Wu, Li, Li, Zheng, Liu, Ye: "Millimeter Wave Treatment Inhibits Apoptosis of Chondrocytes via Regulation Dynamic Equilibrium of Intracellular Free Ca (2+)." in: Evidence-based complementary and alternative medicine : eCAM, Vol. 2015, pp. 464161, 2015

Cai, Zhang, Zhang, Ge, Dai, Tan, Roodrajeetsing, Cai: "Promoting Effects on Proliferation and Chondrogenic Differentiation of Bone Marrow-Derived Mesenchymal Stem Cells by Four "Kidney-Tonifying" Traditional Chinese Herbs." in: BioMed research international, Vol. 2015, pp. 792161, 2015

Liu, Liu, Lin, Wei, Zheng: "Effect of JEZTC, a synthetic compound, on proliferation and phenotype maintenance of rabbit articular chondrocytes in vitro." in: In vitro cellular & developmental biology. Animal, Vol. 50, Issue 10, pp. 982-91, 2014

Ye, Hao, Song, Zhao, Fang, Wang, Li: "Microenvironment is involved in cellular response to hydrostatic pressures during chondrogenesis of mesenchymal stem cells." in: Journal of cellular biochemistry, Vol. 115, Issue 6, pp. 1089-96, 2014

Zhang, Zhang, Shi, Tan, Han, Ye, Pan, Sun, Liu: "Comparisons of rabbit bone marrow mesenchymal stem cell isolation and culture methods in vitro." in: PLoS ONE, Vol. 9, Issue 2, pp. e88794, 2014

Han, Zhang, Wang, Lv, Xu: "Effect of the human insulin-like growth factor 1 gene transfection to human umbilical cord blood mesenchymal stem cells." in: Saudi medical journal, Vol. 35, Issue 5, pp. 435-41, 2014

Qian, Liang, Wang, Wang: "Effect of passive motion on articular cartilage in rat osteoarthritis." in: Experimental and therapeutic medicine, Vol. 8, Issue 2, pp. 377-383, 2014

Fu, Liu, Yang, Wang, Yuan, Lin, Jiang: "Interleukin-18-induced inflammatory responses in synoviocytes and chondrocytes from osteoarthritic patients." in: International journal of molecular medicine, Vol. 30, Issue 4, pp. 805-10, 2012

Li, Wang, Zou, Zhang, Long, Lei, Tan, Ye, Wang, Zhao: "The influence of delayed compressive stress on TGF-?1-induced chondrogenic differentiation of rat BMSCs through Smad-dependent and Smad-independent pathways." in: Biomaterials, Vol. 33, Issue 33, pp. 8395-405, 2012

You, Peng, Li, Ma, Wang, Shu, Peng, Chen: "Chondrogenic differentiation of human bone marrow mesenchymal stem cells on polyhydroxyalkanoate (PHA) scaffolds coated with PHA granule binding protein PhaP fused with RGD peptide." in: Biomaterials, Vol. 32, Issue 9, pp. 2305-13, 2011

Chen, Yang, Liao, Zeng, Liang, Kang, Tan, Liang: "MRI and histologic analysis of collagen type II sponge on repairing the cartilage defects of rabbit knee joints." in: Journal of biomedical materials research. Part B, Applied biomaterials, Vol. 96, Issue 2, pp. 267-75, 2011

Li, Guo, He, Tuo, Wang, Wen, Jin: "In vitro chondrogenesis of the goat bone marrow mesenchymal stem cells directed by chondrocytes in monolayer and 3-dimetional indirect co-culture system." in: Chinese medical journal, Vol. 124, Issue 19, pp. 3080-6, 2011

Zhang, Ding, Shi, Li, Haom, Ke, Tang: "Effects of exogenous urotensin II on vascular remodelling after balloon injury." in: Clinical and experimental pharmacology & physiology, Vol. 37, Issue 4, pp. 477-81, 2010

Li, Du, Liu, Wu, Ye, Lin, Chen, Wu: "Millimeter wave treatment inhibits NO-induced apoptosis of chondrocytes through the p38MAPK pathway." in: International journal of molecular medicine, Vol. 25, Issue 3, pp. 393-9, 2010

Li, Yang, Wu, Zhang, Jiang, Ma, Chen, Xu, Li, Hua: "Proteomic analysis of early-response to mechanical stress in neonatal rat mandibular condylar chondrocytes." in: Journal of cellular physiology, Vol. 223, Issue 3, pp. 610-22, 2010

Lin, Fu, Zhang, Wang, Liu, Zhou, Duan, Wang, Wu, Wang: "Tumourigenesis in the infarcted rat heart is eliminated through differentiation and enrichment of the transplanted embryonic stem cells." in: European journal of heart failure, Vol. 12, Issue 11, pp. 1179-85, 2010