anti-Rind (Kuh) COL2A1 Antikörper für Immunohistochemistry (Frozen Sections)

Recommended COL2A1 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Collagen, Type II, alpha 1 (COL2A1) Antikörper
  • COL2A1
  • Col2
  • Col2a
  • Col2a-1
  • Del1
  • Dmm
  • Lpk
  • M100856
  • Rgsc856
  • ANFH
  • AOM
  • COL11A3
  • SEDC
  • CG2A1A
  • COLLII
  • CB11
  • col2a1a
  • collagen, type II, alpha 1
  • type II Collagen
  • col2a1
  • col2a1b
  • COL2A1
  • Col2a1
  • LOC100009005
Epitop
Chain alpha 1
17
14
13
10
4
4
3
2
2
2
2
2
1
1
1
Reaktivität
Rind (Kuh), Human, Kaninchen, Ratte (Rattus)
54
35
30
7
3
3
3
2
2
Wirt
Maus
67
6
1
1
Klonalität
Monoklonal
Konjugat
Dieser COL2A1 Antikörper ist unkonjugiert
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Applikation
Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
48
24
21
17
17
15
15
13
9
7
6
5
1
Hersteller
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Hersteller Produkt- Nr.
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Bilder

Produktnummer ABIN567566
$ 357.50
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
1 ABIN116553 EIA IHC (fro) WB Biotin Rabbit Chain alpha 1 Anmelden zum Anzeigen Polyclonal
1 ABIN2487213 EIA IHC (fro) IHC (p) RIA Rabbit Chain alpha 1 Anmelden zum Anzeigen Polyclonal
1 ABIN1450180 EIA IHC (fro) IHC (p) IP WB Rabbit Chain alpha 1 Anmelden zum Anzeigen Polyclonal
1 ABIN116552 EIA IHC (fro) IHC (p) IP WB Rabbit Chain alpha 1 Anmelden zum Anzeigen Polyclonal
1 ABIN5540217 EIA IHC (fro) IHC (p) RIA Rabbit Anmelden zum Anzeigen Polyclonal

General

Antigen Collagen, Type II, alpha 1 (COL2A1) Antikörper
Epitop Chain alpha 1
(17), (14), (13), (10), (4), (4), (3), (2), (2), (2), (2), (2), (1), (1), (1)
Reaktivität Rind (Kuh), Human, Kaninchen, Ratte (Rattus)
(54), (35), (30), (7), (3), (3), (3), (2), (2)
Wirt Maus
(67), (6), (1), (1)
Klonalität (Klon)
Monoklonal   ( )
Konjugat Dieser COL2A1 Antikörper ist unkonjugiert
(2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Applikation Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(48), (24), (21), (17), (17), (15), (15), (13), (9), (7), (6), (5), (1)
Pubmed 7 Publikationen vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-COL2A1 Antikörper

Target Details COL2A1 Anwendungsinformationen Handhabung Referenzen für anti-COL2A1 Antikörper (ABIN567566) Bilder
Spezifität The antibody specifically reacts with Collagen type II from human costal cartilage.
Kreuzreaktivität (Details) Species reactivity (tested):Human, Rabbit, Bovine, and Rat.
Reinigung Affinity Chromatography on Protein A.
Klon II-4C11
Isotyp IgG1

Target Details COL2A1

Produktdetails anti-COL2A1 Antikörper Anwendungsinformationen Handhabung Referenzen für anti-COL2A1 Antikörper (ABIN567566) Bilder zurück nach oben
Antigen
Hintergrund Collagens are highly conserved throughout evolution and are characterized by an uninterrupted "Glycine-X-Y" triplet repeat that is a necessary part of the triple helical structure. For these reasons it is often extremely difficult to generate antibodies with specificities to collagens. The development of type specific antibodies is dependent on NON DENATURED three dimensional epitopes. This may result in diminished reactivity of some antibodies with denatured collagen or formalin fixed, paraffin embedded tissues. Type II collagen is a fibrillar collagen found in cartilage and the vitreous humor of the eye. Collagen type II is essential for the normal embryonic development of the skeleton, for linear growth and for the ability of cartilage to resist compressive forces. Mutations in this gene are associated with achondrogenesis, chondrodysplasia, early onset familial osteoarthritis, SED congenita, Langer Saldino achondrogenesis, Kniest dysplasia, Stickler syndrome type I, and spondyloepimetaphyseal dysplasia Strudwick type. In addition, defects in processing chondrocalcin, a calcium binding protein that is the C propeptide of this collagen molecule, are also associated with chondrodysplasia. There are two transcripts identified for this gene.Synonyms: Alpha-1 type II collagen, COL2A1
Gen-ID 1280
Pathways Sensory Perception of Sound, Growth Factor Binding

Anwendungsinformationen

Produktdetails anti-COL2A1 Antikörper Target Details COL2A1 Handhabung Referenzen für anti-COL2A1 Antikörper (ABIN567566) Bilder zurück nach oben
Applikationshinweise Optimal working dilution should be determined by the investigator.
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-COL2A1 Antikörper Target Details COL2A1 Anwendungsinformationen Referenzen für anti-COL2A1 Antikörper (ABIN567566) Bilder zurück nach oben
Konzentration 0.5 mg/mL
Buffer 0.1 M Na-Phosphate buffer, pH 7.0, 0.5 % BSA (protease-free)

Referenzen für anti-COL2A1 Antikörper (ABIN567566)

Produktdetails anti-COL2A1 Antikörper Target Details COL2A1 Anwendungsinformationen Handhabung Bilder zurück nach oben
Produkt verwendet in:

Guo, Lu, Ji, Ma, Dong, Tu, Guo, Qiu, Wu, Zhang: "Low intensity pulse ultrasound stimulate chondrocytes growth in a 3-D alginate scaffold through improved porosity and permeability." in: Ultrasonics, Vol. 58, pp. 43-52, 2015

Kleinhans, Mohan, Vacun, Schwarz, Haller, Sun, Kahlig, Kluger, Finne-Wistrand, Walles, Hansmann: "A perfusion bioreactor system efficiently generates cell-loaded bone substitute materials for addressing critical size bone defects." in: Biotechnology journal, 2015

Sieker, Kunz, Weißenberger, Gilbert, Frey, Rudert, Steinert: "Direct bone morphogenetic protein 2 and Indian hedgehog gene transfer for articular cartilage repair using bone marrow coagulates." in: Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society, Vol. 23, Issue 3, pp. 433-42, 2015

Bleil, Sieper, Maier, Schlichting, Hempfing, Syrbe, Appel: "Cartilage in facet joints of patients with ankylosing spondylitis (AS) shows signs of cartilage degeneration rather than chondrocyte hypertrophy: implications for joint remodeling in AS." in: Arthritis research & therapy, Vol. 17, pp. 170, 2015

Yan, Silva-Correia, Oliveira, Vilela, Pereira, Sousa, Mano, Oliveira, Oliveira, Reis: "Bilayered silk/silk-nanoCaP scaffolds for osteochondral tissue engineering: In vitro and in vivo assessment of biological performance." in: Acta biomaterialia, Vol. 12, pp. 227-41, 2014

Allgemeine Veröffentlichungen

Kumagai, Sarkar, Uhthoff, Okawara, Ooshima: "Immunohistochemical distribution of type I, II and III collagens in the rabbit supraspinatus tendon insertion." in: Journal of anatomy, Vol. 185 ( Pt 2), pp. 279-84, 1994

Burgeson, Hollister: "Collagen heterogeneity in human cartilage: identification of several new collagen chains." in: Biochemical and biophysical research communications, Vol. 87, Issue 4, pp. 1124-31, 1979

Bilder

Produktdetails anti-COL2A1 Antikörper Target Details COL2A1 Anwendungsinformationen Handhabung Referenzen für anti-COL2A1 Antikörper (ABIN567566) zurück nach oben
Bilder des Herstellers
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Collagen, Type II, alpha 1 (COL2A1) (Chain alpha 1) antibody (ABIN567566) Immunohistochemistry on human trachea paraffin sections using Collagen type II antibo...